(Q34368209)

1 August 2017

1 reference

title

Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage (English)

1 reference

1 August 2017

0 references

Kiyotsugu Yoshida

1

1 reference

PubMed ID

15546503

1 August 2017

Yoshio Miki

series ordinal

2

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1 August 2017

1 November 2004

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1 August 2017

1 reference

1 August 2017

95

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1 August 2017

866-871

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1 August 2017

11

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BRCA1 gene in breast cancer

1 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Identification of the breast cancer susceptibility gene BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

THE GENETICS OF BREAST CANCER SUSCEPTIBILITY

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

BRCA2 mutations in primary breast and ovarian cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Association of BRCA1 with Rad51 in mitotic and meiotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Genetic analysis of BRCA1 function in a defined tumor cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Independence of R/M/N focus formation and the presence of intact BRCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Direct DNA binding by Brca1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Brca1 controls homology-directed DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Megabase chromatin domains involved in DNA double-strand breaks in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Genomic instability in mice lacking histone H2AX

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

BRCA2 is required for homology-directed repair of chromosomal breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Evidence for a transcriptional activation function of BRCA1 C-terminal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

BRCA1 is a component of the RNA polymerase II holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

Transcriptional activation by BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2004.TB02195.X

10.1111/J.1349-7006.2004.TB02195.X

21 January 2018

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

15546503