(Q34381235)

1 August 2017

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title

Galectins as modulators of tumour progression (English)

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1 August 2017

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1

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Gabriel Rabinovich

series ordinal

2

object named as

Gabriel A Rabinovich

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1 August 2017

language of work or name

English

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publication date

1 January 2005

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1 August 2017

published in

Nature Reviews Cancer

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1 August 2017

volume

5

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1 August 2017

issue

1

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1 August 2017

page(s)

29-41

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1 August 2017

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History of lectins: from hemagglutinins to biological recognition molecules

31 March 2020

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Progress in deciphering the information content of the 'glycome'--a crescendo in the closing years of the millennium

31 March 2020

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Galectins: a family of animal beta-galactoside-binding lectins

31 March 2020

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Galectinomics: finding themes in complexity

31 March 2020

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Introduction to galectins

31 March 2020

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Phylogenetic analysis of the vertebrate galectin family.

31 March 2020

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New animal lectin structures

31 March 2020

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Oligosaccharide specificity of galectins: a search by frontal affinity chromatography.

31 March 2020

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Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous cross-linked complexes

31 March 2020

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Clusters, bundles, arrays and lattices: novel mechanisms for lectin-saccharide-mediated cellular interactions

31 March 2020

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Evidence for export of a muscle lectin from cytosol to extracellular matrix and for a novel secretory mechanism

31 March 2020

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Secretion of the galectin family of mammalian carbohydrate-binding proteins

31 March 2020

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Intracellular functions of galectins

31 March 2020

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Galectin genes: regulation of expression.

31 March 2020

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31 March 2020

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Expression of galectins in cancer: a critical review

31 March 2020

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Tumor galectinology: insights into the complex network of a family of endogenous lectins

31 March 2020

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Human galectin-8 isoforms and cancer

31 March 2020

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Galectins and urological cancer

31 March 2020

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Galectins as modulators of cell adhesion

31 March 2020

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Induction of terminal differentiation in epithelial cells requires polymerization of hensin by galectin 3

31 March 2020

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Shuttling of galectin-3 between the nucleus and cytoplasm.

31 March 2020

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Identification of galectin-3 as a factor in pre-mRNA splicing

31 March 2020

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Evidence for a role for galectin-1 in pre-mRNA splicing

31 March 2020

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Nucleocytoplasmic lectins

31 March 2020

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Malignant transformation of thyroid follicular cells by galectin-3.

31 March 2020

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Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation

31 March 2020

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Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity

31 March 2020

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Galectin-1 Augments Ras Activation and Diverts Ras Signals to Raf-1 at the Expense of Phosphoinositide 3-Kinase

31 March 2020

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An anti-apoptotic role for galectin-3 in diffuse large B-cell lymphomas

31 March 2020

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Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs.

31 March 2020

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Inhibition of N-(4-hydroxyphenyl)retinamide-induced apoptosis in breast cancer cells by galectin-3.

31 March 2020

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Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation

31 March 2020

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Galectin-3 overexpression protects from cell damage and death by influencing mitochondrial homeostasis.

31 March 2020

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Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest

31 March 2020

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Expression of galectin-3 modulates T-cell growth and apoptosis

31 March 2020

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Dual activities of galectin-3 in human prostate cancer: tumor suppression of nuclear galectin-3 vs tumor promotion of cytoplasmic galectin-3.

31 March 2020

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Galectins in cell growth and apoptosis

31 March 2020

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Galectin-7 overexpression is associated with the apoptotic process in UVB-induced sunburn keratinocytes

31 March 2020

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Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome c release

31 March 2020

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Galectin-12, an Adipose-expressed Galectin-like Molecule Possessing Apoptosis-inducing Activity

31 March 2020

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Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses.

31 March 2020

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Pathways of apoptotic and non-apoptotic death in tumour cells

31 March 2020

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Cell cycle arrest and induction of apoptosis by beta galactoside binding protein (beta GBP) in human mammary cancer cells. A potential new approach to cancer control

31 March 2020

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Negative regulation of neuroblastoma cell growth by carbohydrate-dependent surface binding of galectin-1 and functional divergence from galectin-3.

31 March 2020

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Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells

31 March 2020

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Effects of galectin-3 expression on growth and tumorigenicity of the prostate cancer cell line LNCaP.

31 March 2020

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Nuclear localization of Galectin-3 in transformed thyroid cells: a role in transcriptional regulation

31 March 2020

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Suppression of tumor growth by galectin-7 gene transfer

31 March 2020

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Galectin-3 enhances cyclin D(1) promoter activity through SP1 and a cAMP-responsive element in human breast epithelial cells

31 March 2020

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Galectin-3, a novel binding partner of beta-catenin

31 March 2020

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Cell cycle regulation by galectin-12, a new member of the galectin superfamily

31 March 2020

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Role of integrins in cell invasion and migration

31 March 2020

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Extracellular functions of galectin-3.

31 March 2020

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Functions of Galectins in Cell Adhesion and Chemotaxis

31 March 2020

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Galectin-8 functions as a matricellular modulator of cell adhesion

31 March 2020

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MDA-MB-435 human breast carcinoma cell homo- and heterotypic adhesion under flow conditions is mediated in part by Thomsen-Friedenreich antigen-galectin-3 interactions.

31 March 2020

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Regulation of cellular adhesion to extracellular matrix proteins by galectin-3.

31 March 2020

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Galectin-8 modulates neutrophil function via interaction with integrin alphaM

31 March 2020

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Galectin-3 overexpression protects from apoptosis by improving cell adhesion properties

31 March 2020

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Effects of the carbohydrate-binding protein galectin-3 on the invasiveness of human breast carcinoma cells

31 March 2020

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Upregulation of galectins-1 and -3 in human colon cancer and their role in regulating cell migration

31 March 2020

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Galectin-1 modulates human glioblastoma cell migration into the brain through modifications to the actin cytoskeleton and levels of expression of small GTPases

31 March 2020

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Galectin-8 expression decreases in cancer compared with normal and dysplastic human colon tissue and acts significantly on human colon cancer cell migration as a suppressor

31 March 2020

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Role of angiogenesis in tumor growth and metastasis

31 March 2020

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Galectin-3 induces endothelial cell morphogenesis and angiogenesis

31 March 2020

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Galectin-3 mediates the endocytosis of beta-1 integrins by breast carcinoma cells

31 March 2020

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Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis.

31 March 2020

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Modulation of the biological functions of galectin-3 by matrix metalloproteinases

31 March 2020

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Metastasis of human colon cancer is altered by modifying expression of the beta-galactoside-binding protein galectin 3.

31 March 2020

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Galectin-3 and metastasis

31 March 2020

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Role of galectin-3 in breast cancer metastasis: involvement of nitric oxide

31 March 2020

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Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression

31 March 2020

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Cancer and the chemokine network

31 March 2020

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Tumour-educated macrophages promote tumour progression and metastasis

31 March 2020

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Tumor Escape from Immune Response: Mechanisms and Targets of Activity

31 March 2020

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Does the immune system see tumors as foreign or self?

31 March 2020

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The immunobiology of cancer immunosurveillance and immunoediting

31 March 2020

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Shedding light on the immunomodulatory properties of galectins: novel regulators of innate and adaptive immune responses.

31 March 2020

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Galectins: a new family of regulators of inflammation

31 March 2020

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C-type lectins and galectins mediate innate and adaptive immune functions: their roles in the complement activation pathway

31 March 2020

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Seeing strangers or announcing "danger": galectin-3 in two models of innate immunity

31 March 2020

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Galectins in parasite infection and allergic inflammation.

31 March 2020

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Galectins and their ligands: amplifiers, silencers or tuners of the inflammatory response?

31 March 2020

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Galectin-1 induces partial TCR zeta-chain phosphorylation and antagonizes processive TCR signal transduction

31 March 2020

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Beta-galactoside-binding protein secreted by activated T cells inhibits antigen-induced proliferation of T cells

31 March 2020

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Apoptosis of T cells mediated by galectin-1.

31 March 2020

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Presentation of Galectin-1 by Extracellular Matrix Triggers T Cell Death

31 March 2020

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Specific inhibition of T-cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin-1

31 March 2020

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Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis

31 March 2020

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Galectin-1 suppresses experimental colitis in mice

31 March 2020

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Amelioration of graft versus host disease by galectin-1.

31 March 2020

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Expression of a specific glycosyltransferase enzyme regulates T cell death mediated by galectin-1.

31 March 2020

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Molecular mechanisms implicated in galectin-1-induced apoptosis: activation of the AP-1 transcription factor and downregulation of Bcl-2.

31 March 2020

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Involvement of CD2 and CD3 in galectin-1 induced signaling in human Jurkat T-cells

31 March 2020

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Galectin-1 induces nuclear translocation of endonuclease G in caspase- and cytochrome c-independent T cell death

31 March 2020

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Dimeric galectin-1 induces surface exposure of phosphatidylserine and phagocytic recognition of leukocytes without inducing apoptosis

31 March 2020

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Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumor-immune privilege

31 March 2020

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Evidence of a role for galectin-1 in acute inflammation

31 March 2020

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A novel biological activity for galectin-1: inhibition of leukocyte-endothelial cell interactions in experimental inflammation.

31 March 2020

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Human galectin-3 is a novel chemoattractant for monocytes and macrophages

31 March 2020

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Maintenance of granulocyte numbers during acute peritonitis is defective in galectin-3-null mutant mice

31 March 2020

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Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma

31 March 2020

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Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation

31 March 2020

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Galectin-3 mediates IL-4-induced survival and differentiation of B cells: functional cross-talk and implications during Trypanosoma cruzi infection.

31 March 2020

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Human galectin-2: novel inducer of T cell apoptosis with distinct profile of caspase activation

31 March 2020

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Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro

31 March 2020

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Induced reactivity of intestinal CD4(+) T cells with an epithelial cell lectin, galectin-4, contributes to exacerbation of intestinal inflammation.

31 March 2020

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Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.

31 March 2020

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Galectin-9 induces apoptosis through the calcium-calpain-caspase-1 pathway

31 March 2020

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Human ecalectin, a variant of human galectin-9, is a novel eosinophil chemoattractant produced by T lymphocytes

31 March 2020

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Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures

31 March 2020

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Peptides specific to the galectin-3 carbohydrate recognition domain inhibit metastasis-associated cancer cell adhesion.

31 March 2020

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Low micromolar inhibitors of galectin-3 based on 3'-derivatization of N-acetyllactosamine

31 March 2020

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Wedgelike glycodendrimers as inhibitors of binding of mammalian galectins to glycoproteins, lactose maxiclusters, and cell surface glycoconjugates

31 March 2020

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Differential regulation of constitutive and retinoic acid-induced galectin-1 gene transcription in murine embryonal carcinoma and myoblastic cells

31 March 2020

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The antimetastatic effect of a single low dose of cyclophosphamide involves modulation of galectin-1 and Bcl-2 expression

31 March 2020

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Tumor-mediated apoptosis of cancer-specific T lymphocytes--reversing the "kiss of death"?

31 March 2020

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Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

31 March 2020

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Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

31 March 2020

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The STATs of cancer--new molecular targets come of age

31 March 2020

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Galectins as inflammatory mediators

31 March 2020

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Galectin-1 accumulation in the ovary carcinoma peritumoral stroma is induced by ovary carcinoma cells and affects both cancer cell proliferation and adhesion to laminin-1 and fibronectin

31 March 2020

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRC1527

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Dimensions Publication ID

1 August 2017

1027571841

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