(Q34381683)

1 August 2017

title

The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway (English)

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1 August 2017

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Michael N Corradetti

1

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1 August 2017

Ken Inoki

series ordinal

2

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1 August 2017

Kun-Liang Guan

series ordinal

3

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1 August 2017

language of work or name

English

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publication date

4 January 2005

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Journal of Biological Chemistry

1 August 2017

published in

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1 August 2017

volume

280

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1 August 2017

issue

11

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1 August 2017

page(s)

9769-9772

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Tor signalling in bugs, brain and brawn

1 August 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.C400557200

Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.C400557200

21 January 2018

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Upstream and downstream of mTOR

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.C400557200

Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.C400557200

Tuberous sclerosis complex: from Drosophila to human disease.

21 January 2018

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Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.C400557200

Rheb is an essential regulator of S6K in controlling cell growth in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

Rheb promotes cell growth as a component of the insulin/TOR signalling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

TSC2: filling the GAP in the mTOR signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

Rheb fills a GAP between TSC and TOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

TSC2 mediates cellular energy response to control cell growth and survival

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.C400557200

AMP-activated protein kinase: the energy charge hypothesis revisited

21 January 2018

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The AMP-activated protein kinase pathway--new players upstream and downstream.

21 January 2018

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Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

Akt regulates growth by directly phosphorylating Tsc2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

Tsc2 is not a critical target of Akt during normal Drosophila development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

Identification of the hypoxia-inducible factor 1 alpha-responsive HGTD-P gene as a mediator in the mitochondrial apoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

Dexamethasone-induced Gene 2 (dig2) Is a Novel Pro-survival Stress Gene Induced Rapidly by Diverse Apoptotic Signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

The Drosophila p70s6k homolog exhibits conserved regulatory elements and rapamycin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

The activated glucocorticoid receptor modulates presumptive autoregulation of ribosomal protein S6 protein kinase, p70 S6K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

Inhibition of p70/p85 S6 kinase activities in T cells by dexamethasone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

DNA-damaging agents cause inactivation of translational regulators linked to mTOR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

The multifaceted role of mTOR in cellular stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400557200

21 January 2018

Identifiers

DOI

10.1074/JBC.C400557200

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1 August 2017

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