(Q34399887)

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Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors

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scholarly article

1 reference

Europe PubMed Central

1 August 2017

Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors (English)

1 reference

Europe PubMed Central

1 August 2017

3-[Isopropyl(4-Methylbenzoyl)Amino]-5-Phenylthiophene-2-Carboxylic Acid

1 reference

ChEBI release 2020-05-28

crystal structure

1 reference

based on heuristic

inferred from title

Hepatitis C virus

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Bichitra Biswal

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author name string

Bichitra K Biswal

1

1 reference

Europe PubMed Central

1 August 2017

Maia M Cherney

2

1 reference

Europe PubMed Central

1 August 2017

Meitian Wang

3

1 reference

Europe PubMed Central

1 August 2017

Laval Chan

4

1 reference

Europe PubMed Central

1 August 2017

Constantin G Yannopoulos

5

1 reference

Europe PubMed Central

1 August 2017

Darius Bilimoria

6

1 reference

Europe PubMed Central

1 August 2017

Olivier Nicolas

7

1 reference

Europe PubMed Central

1 August 2017

Jean Bedard

8

1 reference

Europe PubMed Central

1 August 2017

Michael N G James

9

1 reference

Europe PubMed Central

1 August 2017

language of work or name

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publication date

2 March 2005

1 reference

Europe PubMed Central

1 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

1 August 2017

280

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Europe PubMed Central

1 August 2017

18202-18210

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Europe PubMed Central

1 August 2017

18

1 reference

Europe PubMed Central

1 August 2017

Candidate targets for hepatitis C virus-specific antiviral therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Structure of the RNA-dependent RNA polymerase of poliovirus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

A mechanism for initiating RNA-dependent RNA polymerization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Crystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase Enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Identification of N,N-disubstituted phenylalanines as a novel class of inhibitors of hepatitis C NS5B polymerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: tertiary amides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Solvent content of protein crystals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Modulation of hepatitis C virus RNA-dependent RNA polymerase activity by structure-based site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

ESPript: analysis of multiple sequence alignments in PostScript

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413410200

21 January 2018

Identifiers

10.1074/JBC.M413410200

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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