(Q34415944)

2 August 2017

2 references

20 August 2019

23 November 2020

Understanding and preventing drug-drug and drug-gene interactions (English)

1 reference

2 August 2017

physiological phenomenon

1 reference

20 August 2019

adverse drug reaction

1 reference

23 November 2020

1

Cara Tannenbaum

1 reference

2 August 2017

Nancy L Sheehan

2

1 reference

PubMed ID

24745854

2 August 2017

language of work or name

English

0 references

publication date

19 April 2014

1 reference

PubMed ID

24745854

Expert Review of Clinical Pharmacology

2 August 2017

1 July 2014

2 references

20 August 2019

23 November 2020

3 references

2 August 2017

20 August 2019

23 November 2020

7

1 reference

2 August 2017

533-544

1 reference

2 August 2017

4

1 reference

Creative Commons Attribution 3.0 Unported

2 August 2017

2 references

20 August 2019

Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 update.

23 November 2020

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Triamcinolone and ritonavir leading to drug-induced Cushing syndrome and adrenal suppression: description of a new case and review of the literature

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Cytochrome P450 2D6 phenoconversion is common in patients being treated for depression: implications for personalized medicine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Pharmacokinetic interaction between telaprevir and methadone

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Challenging the FDA black box warning for high aspirin dose with ticagrelor in patients with diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

An evaluation of pharmacists' expectations towards pharmacogenomics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

A randomized and clinical effectiveness trial comparing two pharmacogenetic algorithms and standard care for individualizing warfarin dosing (CoumaGen-II).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Gilbert syndrome redefined: a complex genetic haplotype influences the regulation of glucuronidation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

A successful model and visual design for creating context-aware drug-drug interaction alerts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Potentially harmful drug-drug interactions in the elderly: a review

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Detection and prevention of drug-drug interactions in the hospitalized elderly: utility of new cytochrome p450-based software

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Prospective evaluation of a pharmacogenetics-guided warfarin loading and maintenance dose regimen for initiation of therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Pharmacogenomics of the triazole antifungal agent voriconazole

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Development of a context model to prioritize drug safety alerts in CPOE systems

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

A critical evaluation of clinical decision support for the detection of drug-drug interactions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Trimethoprim/sulfamethoxazole-induced phenytoin toxicity in the elderly: a population-based study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

The risk of hypotension following co-prescription of macrolide antibiotics and calcium-channel blockers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Ability of pharmacy clinical decision-support software to alert users about clinically important drug-drug interactions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Pharmacogenetics of cytochrome P450 (CYP) in the elderly

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Anti-infectives and the risk of severe hypoglycemia in users of glipizide or glyburide

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Xenobiotic, bile acid, and cholesterol transporters: function and regulation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

The complexities of antiretroviral drug-drug interactions: role of ABC and SLC transporters

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Warfarin with fluoroquinolones, sulfonamides, or azole antifungals: interactions and the risk of hospitalization for gastrointestinal bleeding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

A randomized trial of the effectiveness of on-demand versus computer-triggered drug decision support in primary care

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

New era in drug interaction evaluation: US Food and Drug Administration update on CYP enzymes, transporters, and the guidance process

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

A mixed method study of the merits of e-prescribing drug alerts in primary care

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Gilbert's Syndrome and irinotecan toxicity: combination with UDP-glucuronosyltransferase 1A7 variants increases risk

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Inhibition of human organic anion transporter 3 mediated pravastatin transport by gemfibrozil and the metabolites in humans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Drug interaction studies: study design, data analysis, and implications for dosing and labeling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Evaluation of the performance of drug-drug interaction screening software in community and hospital pharmacies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Drug-associated disease: cytochrome P450 interactions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interaction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

The role of transporters in drug interactions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Drug-drug interactions among recently hospitalised patients--frequent but mostly clinically insignificant

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

UDP-glucuronosyltransferases and clinical drug-drug interactions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Identification of serious drug-drug interactions: results of the partnership to prevent drug-drug interactions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Evaluation of HIV drug interaction web sites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Drug interactions: Proteins, pumps, and P-450s

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Induction of zidovudine glucuronidation and amination pathways by rifampicin in HIV-infected patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Improving prescribing patterns for the elderly through an online drug utilization review intervention: a system linking the physician, pharmacist, and computer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

The effect of ferrous sulphate on the absorption of norfloxacin, ciprofloxacin and ofloxacin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

CYP3A gene expression in human gut epithelium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Torsades de pointes occurring in association with terfenadine use

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Rifampin, oral contraceptives, and pregnancy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

Assessment of potential drug-drug interactions with a prescription claims database

6 July 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Pharmacokinetic interaction between zidovudine and valproic acid in patients infected with human immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Severe anemia secondary to a probable drug interaction between zidovudine and valproic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Identification of the Cytochrome P450 Enzymes Involved in theN-Oxidation of Voriconazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Hemorrhage during warfarin therapy associated with cotrimoxazole and other urinary tract anti-infective agents: a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Drug-drug interactions among elderly patients hospitalized for drug toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Rhabdomyolysis with HMG-CoA reductase inhibitors and gemfibrozil combination therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Potential for drug interactions involving cytochromes P450 2D6 and 3A4 on general adult psychiatric and functional elderly psychiatric wards.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Prevalence of patients using drugs metabolized by cytochrome P450 2D6 in different populations: a cross-sectional study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

The impact of interacting drugs on dispensed doses of warfarin in the Swedish population: A novel use of population based drug registers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Impact of the drug-drug interaction database SFINX on prevalence of potentially serious drug-drug interactions in primary health care

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Warfarin interactions with substances listed in drug information compendia and in the FDA-approved label for warfarin sodium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Checklist for standardized reporting of drug-drug interaction management guidelines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinide

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17512433.2014.910111

Delivering pharmacogenetic testing in a primary care setting.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894065

The relationship between number of drugs and potential drug-drug interactions in the elderly: a study of over 600,000 elderly patients from the Swedish Prescribed Drug Register

27 October 2018

1 reference

12 December 2020

Gilbert's disease and atazanavir: from phenotype to UDP-glucuronosyltransferase haplotype

1 reference

12 December 2020

In vivo drug-drug interaction studies--a survey of all new molecular entities approved from 1987 to 1997

1 reference

12 December 2020

Drug-drug interactions related to hospital admissions in older adults: a prospective study of 1000 patients

1 reference

12 December 2020

Effects of rifabutin and rifampicin on the pharmacokinetics of ethinylestradiol and norethindrone

1 reference

12 December 2020

Concurrent use of nonsteroidal anti-inflammatory drugs and oral anticoagulants places elderly persons at high risk for hemorrhagic peptic ulcer disease

1 reference

12 December 2020

Prevalence and risk of potential cytochrome P450-mediated drug-drug interactions in older hospitalized patients with polypharmacy

1 reference

12 December 2020

Quality of drug interaction alerts in prescribing and dispensing software

1 reference

12 December 2020

Recommendations for generating, evaluating, and implementing drug-drug interaction evidence

1 reference

12 December 2020

Effects of rifampicin and cimetidine on pharmacokinetics and pharmacodynamics of lamotrigine in healthy subjects

1 reference

12 December 2020

Pravastatin and gemfibrozil alone and in combination for the treatment of hypercholesterolemia

1 reference

12 December 2020

Effect of low-dose omeprazole (20 mg daily) on the pharmacokinetics of multiple-dose atazanavir with ritonavir in healthy subjects

1 reference

12 December 2020

Clinical study of lamotrigine and valproic acid in patients with epilepsy: using a drug interaction to advantage?

1 reference

12 December 2020

Inhibitory metabolic drug interactions with newer psychotropic drugs: inclusion in package inserts and influences of concurrence in drug interaction screening software

1 reference

12 December 2020

GPs' views on computerized drug interaction alerts: questionnaire survey

1 reference

12 December 2020

Trends in new drug interactions for pharmaceutical products in Japan

1 reference

12 December 2020

10.1586/17512433.2014.910111

Identifiers

DOI

1 reference

2 August 2017

1 reference

2 August 2017

1 reference

PubMed ID

24745854