(Q34424619)

English

Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).

scientific article

Statements

Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib). (English)
Penning TD
Bertenshaw SR
Collins PW
Graneto MJ
Malecha JW
Miyashiro JM
Rogers RS
Rogier DJ
AndersonGD
Burton EG
Cogburn JN
Gregory SA
Koboldt CM
Perkins WE
Seibert K
Veenhuizen AW
Isakson PC
1347-1365

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