(Q34431518)

2 August 2017

Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease (English)

1 reference

2 August 2017

0 references

pulmonary hypertension

1 reference

Gregory J Kato

2

0 references

Mark T. Gladwin

10

object named as

Mark T Gladwin

1 reference

2 August 2017

8

Elliott P Vichinsky

1 reference

2 August 2017

Claudia R Morris

1

1 reference

2 August 2017

Mirjana Poljakovic

3

1 reference

2 August 2017

Xunde Wang

4

1 reference

2 August 2017

William C Blackwelder

5

1 reference

2 August 2017

Vandana Sachdev

6

1 reference

2 August 2017

Stanley L Hazen

7

1 reference

2 August 2017

Sidney M Morris

9

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 July 2005

1 reference

The Journal of the American Medical Association

2 August 2017

1 reference

2 August 2017

294

1 reference

2 August 2017

81-90

1 reference

2 August 2017

1

1 reference

The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Effect of fetal hemoglobin on microvascular regulation in sickle transgenic-knockout mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

The endothelial biology of sickle cell disease: inflammation and a chronic vasculopathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Differential expression of E- and P-selectin in the microvasculature of sickle cell transgenic mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Biological activity of nitric oxide in the plasmatic compartment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Blood mononuclear cell gene expression profiles characterize the oxidant, hemolytic, and inflammatory stress of sickle cell disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Cytokines in sickle cell disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Arginase and asthma: novel insights into nitric oxide homeostasis and airway hyperresponsiveness

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Role of Th2 responses in the development of allergen-induced airway remodelling in a murine model of allergic asthma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

An emerging role for nitric oxide in sickle cell disease vascular homeostasis and therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Divergent nitric oxide bioavailability in men and women with sickle cell disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Regulation of enzymes of the urea cycle and arginine metabolism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Increased arginase activity underlies allergen-induced deficiency of cNOS-derived nitric oxide and airway hyperresponsiveness

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Expression, regulation and function of carrier proteins for cationic amino acids.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

P-selectin mediates the adhesion of sickle erythrocytes to the endothelium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Regulation of nitric oxide production by arginine metabolic enzymes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Haemolytic uraemic syndrome and pulmonary hypertension in a patient with methionine synthase deficiency

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Arginine metabolism: nitric oxide and beyond

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Nitric oxide deficiency in fenfluramine- and dexfenfluramine-induced pulmonary hypertension.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Tissue factor expression by endothelial cells in sickle cell anemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Airway hyperreactivity in children with sickle cell disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Regulation of lipid metabolism by cytokines during host defense

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Short-term pulmonary vasodilation with L-arginine in pulmonary hypertension.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Microangiopathic Hemolytic Anemia and Thrombocytopenia in Primary Pulmonary Hypertension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Relative importance of kidney and liver in synthesis of arginine by the rat

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Primary pulmonary hypertension. Its association with microangiopathic hemolytic anemia and thrombocytopenia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Ca2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

The contribution of endothelial cell P-selectin to the microvascular flow of mouse sickle erythrocytes in vivo.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Lipoprotein remnants and endothelial dysfunction in the postprandial phase

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Endothelial cell adhesion molecules in healthy adults during acute hyperhomocysteinemia and mild hypertriglyceridemia

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Decreased arginine bioavailability and increased serum arginase activity in asthma

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Evidence for a metabolic shift of arginine metabolism in sickle cell disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Pulmonary hypertension as a risk factor for death in patients with sickle cell disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Effects of fenofibrate on endothelial function and cell adhesion molecules during post-prandial lipemia in hypertriglyceridemia.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Reduced cholesterol levels in African-American adults with sickle cell disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Hydroxyurea and arginine therapy: impact on nitric oxide production in sickle cell disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Hemolytic anemia-associated pulmonary hypertension of sickle cell disease and the nitric oxide/arginine pathway

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease?

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Pulmonary hypertension in sickle cell disease: cardiac catheterization results and survival

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Expression of the liver form of arginase in erythrocytes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Renal pathology in hemizygous sickle cell mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Recurrent thromboembolic disease following splenectomy for pyruvate kinase deficiency

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Prevalence and reversibility of lower airway obstruction in children with sickle cell disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Patterns of arginine and nitric oxide in patients with sickle cell disease with vaso-occlusive crisis and acute chest syndrome

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Th1 and Th2 cytokine profiles in sickle cell disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Serum and urinary amino acid levels in sickle cell disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Pulmonary hypertension and right heart failure in patients with beta-thalassemia intermedia.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Spherocytosis and pulmonary hypertension coincidental occurrence or causal relationship?

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2065861

Role of nitric oxide in the local regulation of pulmonary vascular resistance in humans

27 October 2018

1 reference

12 December 2020

The release of nitric oxide and superoxide anion by neutrophils and mononuclear cells from patients with sickle cell anaemia

1 reference

12 December 2020

Renal nitric oxide synthases in transgenic sickle cell mice

1 reference

12 December 2020

Circulating activated endothelial cells in sickle cell anemia

1 reference

12 December 2020

Biochemical reaction products of nitric oxide as quantitative markers of primary pulmonary hypertension

1 reference

12 December 2020

The arginase activity of erythrocytes and leukocytes with particular reference to pernicious anemia and thalassemia major

1 reference

12 December 2020

ENZYMATIC ACTIVITIES OF THE BLOOD SERUM IN THALASSEMIA AND IN THALASSODREPANOCYTOSIS

1 reference

12 December 2020

Impaired nitric oxide-mediated vasodilation in transgenic sickle mouse

1 reference

12 December 2020

Arginine therapy: a novel strategy to induce nitric oxide production in sickle cell disease

1 reference

12 December 2020

Arginase activity in erythrocytes of healthy and ill children

1 reference

12 December 2020

Pulmonary hypertension in paroxysmal nocturnal hemoglobinuria

1 reference

12 December 2020

Pulmonary hypertension in sickle cell disease

1 reference

12 December 2020

Identifiers

DOI

10.1001/JAMA.294.1.81

1 reference

2 August 2017

1 reference

2 August 2017

1 reference