(Q34454224)

English

Production of the antitumor drug epirubicin (4'-epidoxorubicin) and its precursor by a genetically engineered strain of Streptomyces peucetius

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scholarly article

1 reference

Europe PubMed Central

2 August 2017

Production of the antitumor drug epirubicin (4'-epidoxorubicin) and its precursor by a genetically engineered strain of Streptomyces peucetius (English)

1 reference

Europe PubMed Central

2 August 2017

Streptomyces peucetius

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3'-Epidaunorubicin

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1 reference

1 reference

1 reference

author name string

Madduri K

1

1 reference

Europe PubMed Central

2 August 2017

Kennedy J

2

1 reference

Europe PubMed Central

2 August 2017

Rivola G

3

1 reference

Europe PubMed Central

2 August 2017

Inventi-Solari A

4

1 reference

Europe PubMed Central

2 August 2017

Filippini S

5

1 reference

Europe PubMed Central

2 August 2017

Zanuso G

6

1 reference

Europe PubMed Central

2 August 2017

Colombo AL

7

1 reference

Europe PubMed Central

2 August 2017

Gewain KM

8

1 reference

Europe PubMed Central

2 August 2017

Occi JL

9

1 reference

Europe PubMed Central

2 August 2017

MacNeil DJ

10

1 reference

Europe PubMed Central

2 August 2017

Hutchinson CR

11

1 reference

Europe PubMed Central

2 August 2017

publication date

1 January 1998

1 reference

Europe PubMed Central

2 August 2017

Nature Biotechnology

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Europe PubMed Central

2 August 2017

16

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Europe PubMed Central

2 August 2017

69-74

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Europe PubMed Central

2 August 2017

1

1 reference

Europe PubMed Central

2 August 2017

https://scigraph.springernature.com/pub.10.1038/nbt0198-69

0 references

Production of a hybrid macrolide antibiotic in Streptomyces ambofaciens and Streptomyces lividans by introduction of a cloned carbomycin biosynthetic gene from Streptomyces thermotolerans

1 reference

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21 January 2018

Generation of polyketide libraries via combinatorial biosynthesis

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

21 January 2018

Effectiveness of anthracycline against experimental prion disease in Syrian hamsters.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

21 January 2018

Production of hybrid glycopeptide antibiotics in vitro and in Streptomyces toyocaensis

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

21 January 2018

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

21 January 2018

Antibiotics that resist resistance

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

New antibiotics from genetically engineered actinomycetes. I. 2-Norerythromycins, isolation and structural determinations

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

An erythromycin derivative produced by targeted gene disruption in Saccharopolyspora erythraea.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

An erythromycin analog produced by reprogramming of polyketide synthesis

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Rational design of peptide antibiotics by targeted replacement of bacterial and fungal domains

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

A macrolide 3-O-acyltransferase gene from the midecamycin-producing species Streptomyces mycarofaciens

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning of the macrolide antibiotic biosynthesis gene acyA, which encodes 3-O-acyltransferase, from Streptomyces thermotolerans and its use for direct fermentative production of a hybrid macrolide antibiotic

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Polyketide synthase gene manipulation: a structure-function approach in engineering novel antibiotics

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis and antitumor properties of new glycosides of daunomycinone and adriamycinone

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional characterization and transcriptional analysis of the dnrR1 locus, which controls daunorubicin biosynthesis in Streptomyces peucetius

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and characterization of the Streptomyces peucetius dnrQS genes encoding a daunosamine biosynthesis enzyme and a glycosyl transferase involved in daunorubicin biosynthesis

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhanced antibiotic production by manipulation of the Streptomyces peucetius dnrH and dnmT genes involved in doxorubicin (adriamycin) biosynthesis

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and characterization of the Streptomyces peucetius dnmZUV genes encoding three enzymes required for biosynthesis of the daunorubicin precursor thymidine diphospho-L-daunosamine

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

The dnrM gene in Streptomyces peucetius contains a naturally occurring frameshift mutation that is suppressed by another locus outside of the daunorubicin-production gene cluster.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure and sequence of the rfb (O antigen) gene cluster of Salmonella serovar typhimurium (strain LT2)

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the dTDP-rhamnose biosynthetic genes encoded in the rfb locus of Shigella flexneri

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning of genes governing the deoxysugar portion of the erythromycin biosynthesis pathway in Saccharopolyspora erythraea (Streptomyces erythreus)

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

The mRNA for the 23S rRNA methylase encoded by the ermE gene of Saccharopolyspora erythraea is translated in the absence of a conventional ribosome-binding site.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Actinoidin A2, a novel glycopeptide: production, preparative HPLC separation and characterization

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Cladinose analogues of sixteen-membered macrolide antibiotics. I. Synthesis of 4-O-alkyl-L-cladinose analogues via glycosylation

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

A bacterial analog of the mdr gene of mammalian tumor cells is present in Streptomyces peucetius, the producer of daunorubicin and doxorubicin

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional analysis of putative beta-ketoacyl:acyl carrier protein synthase and acyltransferase active site motifs in a type II polyketide synthase of Streptomyces glaucescens

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene disruption and gene replacement in Streptomyces via single stranded DNA transformation of integration vectors

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Compilation and analysis of DNA sequences associated with apparent streptomycete promoters

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

A comprehensive set of sequence analysis programs for the VAX

1 reference

https://api.crossref.org/works/10.1038%2FNBT0198-69

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/NBT0198-69

1 reference

Europe PubMed Central

2 August 2017

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1 reference

Europe PubMed Central

2 August 2017

ResearchGate publication ID

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