(Q34464530)

2 August 2017

WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1. (English)

1 reference

2 August 2017

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Tetsuo Moriguchi

1

1 reference

2 August 2017

Seiichi Urushiyama

2

1 reference

2 August 2017

Naoki Hisamoto

3

1 reference

2 August 2017

Shun-ichiro Iemura

4

1 reference

2 August 2017

Shinichi Uchida

5

1 reference

2 August 2017

Tohru Natsume

6

1 reference

2 August 2017

Kunihiro Matsumoto

7

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2 August 2017

Hiroshi Shibuya

8

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2 August 2017

language of work or name

English

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publication date

31 October 2005

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Journal of Biological Chemistry

2 August 2017

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2 August 2017

280

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2 August 2017

42685-42693

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2 August 2017

52

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WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II

2 August 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

WNK kinases, a novel protein kinase subfamily in multi-cellular organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Human hypertension caused by mutations in WNK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Regulation of apical localization of the thiazide-sensitive NaCl cotransporter by WNK4 in polarized epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

WNK1 activates ERK5 by an MEKK2/3-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

WNK1 activates SGK1 to regulate the epithelial sodium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

WNK1 activates SGK1 by a phosphatidylinositol 3-kinase-dependent and non-catalytic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Molecular physiology of cation-coupled Cl? cotransport: the SLC12 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

The Na-K-Cl cotransporter of secretory epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Cloning of sgk serine-threonine protein kinase from shark rectal gland – a gene induced by hypertonicity and secretagogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

PASK (Proline-Alanine-rich STE20-related Kinase), a Regulatory Kinase of the Na-K-Cl Cotransporter (NKCC1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

A conserved docking motif in MAP kinases common to substrates, activators and regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

The Ste20 group kinases as regulators of MAP kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Advances in protein kinase B signalling: AKTion on multiple fronts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510042200

21 January 2018

Identifiers

DOI

10.1074/JBC.M510042200

1 reference

2 August 2017

1 reference