(Q34474600)

English

Phase ii, randomized, placebo-controlled, 90-day study of emixustat hydrochloride in geographic atrophy associated with dry age-related macular degeneration

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Phase ii, randomized, placebo-controlled, 90-day study of emixustat hydrochloride in geographic atrophy associated with dry age-related macular degeneration (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

0 references

macular degeneration

1 reference

based on heuristic

inferred from title

geographic atrophy

1 reference

based on heuristic

inferred from title

author name string

Pravin U Dugel

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Roger L Novack

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Karl G Csaky

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Preston P Richmond

4

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

David G Birch

5

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Ryo Kubota

6

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

publication date

1 June 2015

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

number of pages

11

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based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

35

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Europe PubMed Central

PubMed publication ID

2 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

1173-1183

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Phase 1, dose-ranging study of emixustat hydrochloride (ACU-4429), a novel visual cycle modulator, in healthy volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Global estimates of visual impairment: 2010.

1 reference

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6 July 2018

Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Prevalence of age-related macular degeneration in the US population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Forecasting age-related macular degeneration through the year 2050: the potential impact of new treatments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

In vivo imaging of foveal sparing in geographic atrophy secondary to age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Fundus autofluorescence and progression of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Progression of geographic atrophy and impact of fundus autofluorescence patterns in age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Correlation between the area of increased autofluorescence surrounding geographic atrophy and disease progression in patients with AMD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

The role of inflammation in the pathogenesis of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Global data on visual impairment in the year 2002

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Fundus autofluorescence and fundus perimetry in the junctional zone of geographic atrophy in patients with age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Prevalence of age-related macular degeneration in the United States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

A2E: a component of ocular lipofuscin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

6 July 2018

Age-Related Macular Degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

27 October 2018

Involvement of oxidative mechanisms in blue-light-induced damage to A2E-laden RPE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

27 October 2018

Inflammation in the pathogenesis of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452434

9 December 2018

Age-related Macular Degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/25932553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rhodopsin cycle in the developing vertebrate retina. I. Relation of rhodopsin content, electroretinogram and rod structure in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/25932553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related macular degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/25932553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does A2E, a retinoid component of lipofuscin and inhibitor of lysosomal degradative functions, directly affect the activity of lysosomal hydrolases?

1 reference

https://pubmed.ncbi.nlm.nih.gov/25932553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of origins of electroretinogram components by intraretinal recording in the intact cat eye

1 reference

https://pubmed.ncbi.nlm.nih.gov/25932553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photocoagulation for diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 1. Early Treatment Diabetic Retinopathy Study research group

1 reference

https://pubmed.ncbi.nlm.nih.gov/25932553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/IAE.0000000000000606

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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