(Q34564994)

3 August 2017

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title

DNA methylation, imprinting and cancer (English)

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3 August 2017

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Christoph Plass

1

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3 August 2017

Paul D Soloway

series ordinal

2

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3 August 2017

language of work or name

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1 January 2002

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European Journal of Human Genetics

3 August 2017

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3 August 2017

10

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3 August 2017

6-16

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3 August 2017

1

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https://scigraph.springernature.com/pub.10.1038/sj.ejhg.5200768

3 August 2017

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cites work

Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Active demethylation of the paternal genome in the mouse zygote

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Imprinted expression of the Igf2r gene depends on an intronic CpG island.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Regulation of DNA methylation of Rasgrf1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

A DNA target of 30 bp is sufficient for RNA-directed DNA methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Gene silencing: repeats that count

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Identification and characterization of a family of mammalian methyl-CpG binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Sin meets NuRD and other tails of repression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Roles of histone acetyltransferases and deacetylases in gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

ATP-Dependent histone octamer mobilization and histone deacetylation mediated by the Mi-2 chromatin remodeling complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

The "dark side" of chromatin remodeling: repressive effects on transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Trichostatin A causes selective loss of DNA methylation in Neurospora

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Transcriptional repression by the insulator protein CTCF involves histone deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Number of CpG islands and genes in human and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Genomic imprinting in mammals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Genomic imprinting in mammals: an interplay between chromatin and DNA methylation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Genomic imprinting: parental influence on the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Role for DNA methylation in genomic imprinting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Asynchronous replication of imprinted genes is established in the gametes and maintained during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Parental chromosome-specific chromatin conformation in the imprinted U2af1-rs1 gene in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Cancer epigenetics comes of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

DNA hypermethylation in tumorigenesis: epigenetics joins genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

The 5-methylcytosine content of highly repeated sequences in human DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Global DNA hypomethylation occurs in the early stages of intestinal type gastric carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Global DNA hypomethylation increases progressively in cervical dysplasia and carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

High sensitivity mapping of methylated cytosines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Global methylation profiling of lung cancer identifies novel methylated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Aberrant promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas--implications for tumor biology and potential clinical utility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Relaxation of imprinted genes in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilms tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Analysis of genomic imprinting of insulin-like growth factor 2 in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Disruption of insulin-like growth factor 2 imprinting in Beckwith-Wiedemann syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Gain of imprinting at chromosome 11p15: A pathogenetic mechanism identified in human hepatocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Suppression of intestinal neoplasia by DNA hypomethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

The imprinting box of the mouse Igf2r gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Substrate and sequence specificity of a eukaryotic DNA methylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

Tandem B1 elements located in a mouse methylation center provide a target for de novo DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

An inverted repeat triggers cytosine methylation of identical sequences in Arabidopsis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Cytosine methylation as an effector of right-handed to left-handed DNA structural transitions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Mechanisms of genomic imprinting

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Epigenetic mechanisms underlying the imprinting of the mouse H19 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Inactive allele-specific methylation and chromatin structure of the imprinted gene U2af1-rs1 on mouse chromosome 11

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Global DNA hypomethylation in breast carcinoma: correlation with prognostic factors and tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Methylation profiling of CpG islands in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Restriction landmark genome scanning for aberrant methylation in primary refractory and relapsed acute myeloid leukemia; involvement of the WIT-1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Epigenetic lesions at the H19 locus in Wilms' tumour patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Loss of imprinting of igf2 in renal-cell carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Mono- and bi-allelic expression of insulin-like growth factor II gene in human muscle tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

IGF2 is parentally imprinted during human embryogenesis and in the Beckwith-Wiedemann syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Parental imprinting of human chromosome region 11p15.3-pter involved in the Beckwith-Wiedemann syndrome and various human neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Evidence for two tumour suppressor loci on chromosomal bands 1p35-36 involved in neuroblastoma: one probably imprinted, another associated with N-myc amplification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Methylation-independent silencing of the p73 gene in neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Expression of DNA methyl-transferase (DMT) and the cell cycle in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5200768

7 January 2021

Identifiers

DOI

10.1038/SJ.EJHG.5200768

1 reference

Dimensions Publication ID

3 August 2017

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1 reference