(Q34565058)

3 August 2017

iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53. (English)

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3 August 2017

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Andrea Bisso

6

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Marketa J Zvelebil

object named as

Marketa Zvelebil

4

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Yardena Samuels

object named as

Yardena Samuels

2

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Giannino Del Sal

object named as

Giannino Del Sal

7

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author name string

Daniele Bergamaschi

1

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3 August 2017

Alexandra Sullivan

3

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3 August 2017

Hilde Breyssens

5

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3 August 2017

Nelofer Syed

8

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3 August 2017

Paul Smith

9

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3 August 2017

Milena Gasco

10

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3 August 2017

Tim Crook

11

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3 August 2017

Xin Lu

12

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3 August 2017

language of work or name

English

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publication date

10 September 2006

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3 August 2017

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3 August 2017

38

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3 August 2017

1133-1141

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3 August 2017

10

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https://scigraph.springernature.com/pub.10.1038/ng1879

3 August 2017

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cites work

To die or not to die: how does p53 decide?

1 reference

7 January 2021

ASPP proteins specifically stimulate the apoptotic function of p53

1 reference

7 January 2021

iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.

1 reference

7 January 2021

Abnormal mRNA expression of ASPP members in leukemia cell lines.

1 reference

7 January 2021

The expression of iASPP in acute leukemias

1 reference

7 January 2021

ASPP1, a common activator of TP53, is inactivated by aberrant methylation of its promoter in acute lymphoblastic leukemia.

1 reference

7 January 2021

Apoptosis stimulating protein of p53 (ASPP2) expression differs in diffuse large B-cell and follicular center lymphoma: correlation with clinical outcome

1 reference

7 January 2021

ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth

1 reference

7 January 2021

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

1 reference

7 January 2021

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

1 reference

7 January 2021

Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity

1 reference

7 January 2021

The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells

1 reference

7 January 2021

The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression

1 reference

7 January 2021

Guinea pig p53 mRNA: identification of new elements in coding and untranslated regions and their functional and evolutionary implications

1 reference

7 January 2021

Association of p53 genetic polymorphism (Arg72Pro) with estrogen receptor positive breast cancer risk in Japanese women

1 reference

7 January 2021

Proline homozygosity in codon 72 of p53 is a factor of susceptibility for thyroid cancer

1 reference

7 January 2021

P53 codon 72 polymorphism and correlation with ovarian and endometrial cancer in Greek women.

1 reference

7 January 2021

Association of p53 arginine polymorphism with skin cancer

1 reference

7 January 2021

TP53 polymorphisms and lung cancer risk: a systematic review and meta-analysis

1 reference

7 January 2021

The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

1 reference

7 January 2021

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis

1 reference

7 January 2021

Evidence for selective expression of the p53 codon 72 polymorphs: implications in cancer development.

1 reference

7 January 2021

ASPP [corrected] and cancer

1 reference

7 January 2021

p53 polymorphisms and haplotypes in different ethnic groups

1 reference

7 January 2021

p53 polymorphisms and haplotypes show distinct differences between major ethnic groups

1 reference

7 January 2021

The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization.

1 reference

7 January 2021

ASPP1 and ASPP2: common activators of p53 family members

1 reference

7 January 2021

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

1 reference

7 January 2021

Identifiers

DOI

10.1038/NG1879

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Dimensions Publication ID

3 August 2017

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1 reference