(Q34572921)

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Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS. (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

amyotrophic lateral sclerosis

1 reference

based on heuristic

inferred from title

superoxide dismutase 1

1 reference

GOA release 2020-03-11

identical protein binding

1 reference

GOA release 2020-03-11

author name string

Kenrick A Vassall

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Helen R Stubbs

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Heather A Primmer

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Ming Sze Tong

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Sarah M Sullivan

5

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Ryan Sobering

6

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Saipraveen Srinivasan

7

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Lee-Ann K Briere

8

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Stanley D Dunn

9

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Wilfredo Colón

10

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Elizabeth M Meiering

11

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

0 references

publication date

21 January 2011

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

108

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

2210-2215

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Nonamyloid aggregates arising from mature copper/zinc superoxide dismutases resemble those observed in amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

SOD1 mutations targeting surface hydrogen bonds promote amyotrophic lateral sclerosis without reducing apo-state stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Biomarkers in amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Initiation and elongation in fibrillation of ALS-linked superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

A limited role for disulfide cross-linking in the aggregation of mutant SOD1 linked to familial amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Protein misfolding and neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Cysteine 111 affects aggregation and cytotoxicity of mutant Cu,Zn-superoxide dismutase associated with familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

BPPred: a Web-based computational tool for predicting biophysical parameters of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

ALS: a disease of motor neurons and their nonneuronal neighbors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Destabilization of apoprotein is insufficient to explain Cu,Zn-superoxide dismutase-linked ALS pathogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Systematically perturbed folding patterns of amyotrophic lateral sclerosis (ALS)-associated SOD1 mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Folding of human superoxide dismutase: disulfide reduction prevents dimerization and produces marginally stable monomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Myoglobin forms amyloid fibrils by association of unfolded polypeptide segments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Rationalization of the effects of mutations on peptide and protein aggregation rates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis show enhanced formation of aggregates in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Familial amyotrophic lateral sclerosis mutants of copper/zinc superoxide dismutase are susceptible to disulfide reduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

New consensus research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 (SOD1) gene mutations: inclusions containing SOD1 in neurons and astrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Hydrodynamic radii of native and denatured proteins measured by pulse field gradient NMR techniques.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Monitoring protein assembly using quasielastic light scattering spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Denaturant m values and heat capacity changes: relation to changes in accessible surface areas of protein unfolding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Scanning microcalorimetry in studying temperature-induced changes in proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Contribution of conformational stability and reversibility of unfolding to the increased thermostability of human and bovine superoxide dismutase mutated at free cysteines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

New ubiquitin-positive intraneuronal inclusions in the extra-motor cortices in patients with amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Stability of proteins: small globular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3038722

7 July 2018

Amyotrophic lateral sclerosis mutations have the greatest destabilizing effect on the apo- and reduced form of SOD1, leading to unfolding and oxidative aggregation.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913021108

21 January 2018

Calorimetric analysis of thermodynamic stability and aggregation for apo and holo amyotrophic lateral sclerosis-associated Gly-93 mutants of superoxide dismutase

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913021108

21 January 2018

Mechanism and thermodynamics of guanidinium chloride-induced denaturation of ALS-associated mutant Cu,Zn superoxide dismutases

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913021108

21 January 2018

Dissociation of human copper-zinc superoxide dismutase dimers using chaotrope and reductant. Insights into the molecular basis for dimer stability

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913021108

21 January 2018

Thiol compounds inhibit the formation of amyloid fibrils by beta 2-microglobulin at neutral pH.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913021108

21 January 2018

Sonication of proteins causes formation of aggregates that resemble amyloid

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913021108

21 January 2018

Fully metallated S134N Cu,Zn-superoxide dismutase displays abnormal mobility and intermolecular contacts in solution

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913021108

21 January 2018

Kinetic stability of Cu/Zn superoxide dismutase is dependent on its metal ligands: implications for ALS.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913021108

21 January 2018

Amyotrophic lateral sclerosis-associated copper/zinc superoxide dismutase mutations preferentially reduce the repulsive charge of the proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21257910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shaken, not stirred: mechanical stress testing of an IgG1 antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/21257910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The unusually stable quaternary structure of human Cu,Zn-superoxide dismutase 1 is controlled by both metal occupancy and disulfide status

1 reference

https://pubmed.ncbi.nlm.nih.gov/21257910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Equilibrium thermodynamic analysis of amyotrophic lateral sclerosis-associated mutant apo Cu,Zn superoxide dismutases

1 reference

https://pubmed.ncbi.nlm.nih.gov/21257910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping the folding free energy surface for metal-free human Cu,Zn superoxide dismutase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21257910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0913021108

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

2011PNAS..108.2210V

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

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