(Q34586418)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18154452%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

review article

1 reference

title

ABC multidrug transporters: structure, function and role in chemoresistance (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18154452%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

main subject

multiple drug resistance

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18154452%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

author name string

Frances J Sharom

series ordinal

1

1 reference

3 August 2017

publication date

1 January 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18154452%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18154452%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18154452%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18154452%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

page(s)

105-127

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18154452%20AND%20SRC:MED&resulttype=core&format=json

The ABC of ABCS: a phylogenetic and functional classification of ABC systems in living organisms

31 December 2019

cites work

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The human ATP-binding cassette (ABC) transporter superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The ABC transporter gene family of Caenorhabditis elegans has implications for the evolutionary dynamics of multidrug resistance in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Mammalian ABC transporters in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The molecular basis of multidrug resistance in cancer: the early years of P-glycoprotein research

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Membrane transporters and channels in chemoresistance and -sensitivity of tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Phosphatidylcholine and phosphatidylethanolamine behave as substrates of the human MDR1 P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Phospholipid flippase activity of the reconstituted P-glycoprotein multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The reconstituted P-glycoprotein multidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

P-glycoprotein (ABCB1) interacts directly with lipid-based anti-cancer drugs and platelet-activating factors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

beta-Amyloid efflux mediated by p-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Involvement of P-glycoprotein in the release of cytokines from peripheral blood mononuclear cells treated with methotrexate and dexamethasone.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Phosphatidylcholine translocase: a physiological role for the mdr2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Portrait of multifaceted transporter, the multidrug resistance-associated protein 1 (MRP1/ABCC1).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Pharmacogenomics of the human ABC transporter ABCG2: from functional evaluation to drug molecular design

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Breast cancer resistance protein (BCRP/ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Multidrug resistance reversal agents

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Binding of Steroid Modulators to Recombinant Cytosolic Domain from Mouse P-Glycoprotein in Close Proximity to the ATP Site

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The molecular interaction of the high affinity reversal agent XR9576 with P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The molecular basis of the action of disulfiram as a modulator of the multidrug resistance-linked ATP binding cassette transporters MDR1 (ABCB1) and MRP1 (ABCC1).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

What have we learnt thus far from mice with disrupted P-glycoprotein genes?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: evaluation using the MDR1A/1B knockout mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Importance of P-glycoprotein at blood-tissue barriers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

P-glycoprotein and Mrp1 collectively protect the bone marrow from vincristine-induced toxicity in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Multidrug transporter ABCG2/breast cancer resistance protein secretes riboflavin (vitamin B2) into milk

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Insight in eukaryotic ABC transporter function by mutation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Molecular insights into the mechanism of ATP-hydrolysis by the NBD of the ABC-transporter HlyB.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Large scale purification of detergent-soluble P-glycoprotein from Pichia pastoris cells and characterization of nucleotide binding properties of wild-type, Walker A, and Walker B mutant proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Characterization of the ATPase activity of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Characterization of the ATPase activity of purified Chinese hamster P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Competitive and non-competitive inhibition of the multidrug-resistance-associated P-glycoprotein ATPase--further experimental evidence for a multisite model

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The effects of lipids and detergents on ATPase-active P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Effects of lipids on ATPase activity of purified Chinese hamster P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Interaction of transported drugs with the lipid bilayer and P-glycoprotein through a solvation exchange mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The catalytic cycle of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Stoichiometry and affinity of nucleotide binding to P-glycoprotein during the catalytic cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Nucleotide binding to the multidrug resistance P-glycoprotein as studied by ESR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Role of the NH2-terminal membrane spanning domain of multidrug resistance protein 1/ABCC1 in protein processing and trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Regulation of function by dimerization through the amino-terminal membrane-spanning domain of human ABCC1/MRP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Three-dimensional structure of P-glycoprotein: the transmembrane regions adopt an asymmetric configuration in the nucleotide-bound state

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

FRET analysis indicates that the two ATPase active sites of the P-glycoprotein multidrug transporter are closely associated.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Cysteines 431 and 1074 are responsible for inhibitory disulfide cross-linking between the two nucleotide-binding sites in human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The "LSGGQ" motif in each nucleotide-binding domain of human P-glycoprotein is adjacent to the opposing walker A sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Purification and 3D structural analysis of oligomeric human multidrug transporter ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Recent progress in understanding the mechanism of P-glycoprotein-mediated drug efflux.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Positively Cooperative Sites for Drug Transport by P‐Glycoprotein with Distinct Drug Specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Simultaneous binding of two different drugs in the binding pocket of the human multidrug resistance P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Do drug substrates enter the common drug-binding pocket of P-glycoprotein through "gates"?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Substrate-induced conformational changes in the transmembrane segments of human P-glycoprotein. Direct evidence for the substrate-induced fit mechanism for drug binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The drug-binding pocket of the human multidrug resistance P-glycoprotein is accessible to the aqueous medium.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Interaction of LDS-751 with P-glycoprotein and mapping of the location of the R drug binding site.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Exploring the structure and function of the P-glycoprotein multidrug transporter using fluorescence spectroscopic tools.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

A general pattern for substrate recognition by P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

A pharmacophore hypothesis for P-glycoprotein substrate recognition using GRIND-based 3D-QSAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Intrinsic fluorescence of the P-glycoprotein multidrug transporter: sensitivity of tryptophan residues to binding of drugs and nucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Multiple drugbinding sites on the R482G isoform of the ABCG2 transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Substrate recognition and transport by multidrug resistance protein 1 (ABCC1).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Molecular modeling correctly predicts the functional importance of Phe594 in transmembrane helix 11 of the multidrug resistance protein, MRP1 (ABCC1).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

An inward-facing conformation of a putative metal-chelate-type ABC transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Structure of an ABC transporter in complex with its binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Structure of a bacterial multidrug ABC transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

ABC transporter architecture and mechanism: implications from the crystal structures of BtuCD and BtuF.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The structures of MsbA: Insight into ABC transporter-mediated multidrug efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

A structural model for the open conformation of the mdr1 P-glycoprotein based on the MsbA crystal structure

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The translocation mechanism of P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Both ATP sites of human P-glycoprotein are essential but not symmetric

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Combined mutation of catalytic glutamate residues in the two nucleotide binding domains of P-glycoprotein generates a conformation that binds ATP and ADP tightly

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The ATP hydrolysis cycle of the nucleotide-binding domain of the mitochondrial ATP-binding cassette transporter Mdl1p.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The power of the pump: mechanisms of action of P-glycoprotein (ABCB1).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The ATP switch model for ABC transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Is the multidrug transporter a flippase?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Quantification and characterization of P-glycoprotein-substrate interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The membrane lipid environment modulates drug interactions with the P-glycoprotein multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

New insights into the drug binding, transport and lipid flippase activities of the p-glycoprotein multidrug transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

ABC transporters in the balance: is there a role in multidrug resistance?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

ABC transporters and drug resistance in leukemia: was P-gp nothing but the first head of the Hydra?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Frequent expression of the multi-drug resistance-associated protein BCRP/MXR/ABCP/ABCG2 in human tumours detected by the BXP-21 monoclonal antibody in paraffin-embedded material

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

ABCG2: determining its relevance in clinical drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Structural, mechanistic and clinical aspects of MRP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Anticancer multidrug resistance mediated by MRP1: recent advances in the discovery of reversal agents

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Breast cancer resistance protein: molecular target for anticancer drug resistance and pharmacokinetics/pharmacodynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Targeting multidrug resistance in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

VX-710 (biricodar) increases drug retention and enhances chemosensitivity in resistant cells overexpressing P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Implications of ATP-binding cassette transporters for brain pharmacotherapies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Drug resistance in brain diseases and the role of drug efflux transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

P-Glycoprotein, a gatekeeper in the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

ABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Single nucleotide polymorphisms of ABCB1 (MDR1) gene and distinct haplotype profile in a West Black African population

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Genetic polymorphisms of the human MDR1 drug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Exon sequencing and high resolution haplotype analysis of ABC transporter genes implicated in drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

A "silent" polymorphism in the MDR1 gene changes substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Quantitative structure--activity relationship analysis and molecular dynamics simulation to functionally validate nonsynonymous polymorphisms of human ABC transporter ABCB1 (P-glycoprotein/MDR1).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

MDR1 G1199A polymorphism alters permeability of HIV protease inhibitors across P-glycoprotein-expressing epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Polymorphisms in the multidrug resistance-1 (MDR1) gene influence the response to atorvastatin treatment in a gender-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The association of common SNPs and haplotypes in the CETP and MDR1 genes with lipids response to fluvastatin in familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

An association study of 43 SNPs in 16 candidate genes with atorvastatin response

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Dual infection with Helicobacter bilis and Helicobacter hepaticus in p-glycoprotein-deficient mdr1a-/- mice results in colitis that progresses to dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

MDR1 Ala893 polymorphism is associated with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Polymorphism in the P-glycoprotein drug transporter MDR1 gene in colon cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The anti-Parkinson drug budipine is exported actively out of the brain by P-glycoprotein in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Common ABCB1 polymorphisms are not associated with multidrug resistance in epilepsy using a gene-wide tagging approach

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

A functional polymorphism within the MRP1 gene locus identified through its genomic signature of positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Frequency of MRP1 genetic polymorphisms and their functional significance in Caucasians: detection of a novel mutation G816A in the human MRP1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Functional analysis of SNPs variants of BCRP/ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Single nucleotide polymorphisms modify the transporter activity of ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Single nucleotide polymorphisms result in impaired membrane localization and reduced atpase activity in multidrug transporter ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Re-evaluation and functional classification of non-synonymous single nucleotide polymorphisms of the human ATP-binding cassette transporter ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The role of the human ABCG2 multidrug transporter and its variants in cancer therapy and toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

ABCG2 pharmacogenetics: ethnic differences in allele frequency and assessment of influence on irinotecan disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Inhibition of the epidermal growth factor receptor increases expression of genes that stimulate inflammation, apoptosis, and cell attachment

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in relation to ABC transporter genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Association of variant ABCG2 and the pharmacokinetics of epidermal growth factor receptor tyrosine kinase inhibitors in cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Association of the BCRP C421A polymorphism with nonpapillary renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

A functional study on polymorphism of the ATP-binding cassette transporter ABCG2: critical role of arginine-482 in methotrexate transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

N-Linked glycosylation of the human ABC transporter ABCG2 on asparagine 596 is not essential for expression, transport activity, or trafficking to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

The controversial association of ABCB1 polymorphisms in refractory epilepsy: An analysis of multiple SNPs in an Irish population

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105

Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.1.105