(Q34614478)

3 August 2017

1 reference

title

Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites (English)

1 reference

3 August 2017

1 reference

4

Bruce N Ames

1 reference

3 August 2017

Jiankang Liu

1

1 reference

3 August 2017

Hani Atamna

series ordinal

2

1 reference

3 August 2017

Hirohiko Kuratsune

series ordinal

3

1 reference

3 August 2017

language of work or name

English

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publication date

1 April 2002

1 reference

Annals of the New York Academy of Sciences

3 August 2017

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3 August 2017

959

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3 August 2017

133-166

1 reference

Oxidants, antioxidants, and the degenerative diseases of aging

3 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Mitochondrial decay in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

The biologic clock: the mitochondria?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Oxidative damage and mitochondrial decay in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Protein oxidation and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Mitochondria, oxygen free radicals, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

A century of mitochondrial research: achievements and perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Oxidative damage in the senescence-accelerated mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Stress, aging, and brain oxidative damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Mitochondrial decay in aging. Reversal through supplementation of acetyl-L-carnitine and N-tert-butyl-alpha-phenyl-nitrone

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Age-dependent changes in the activity of anion carriers and in the lipid composition in rat heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Possible confounding influence of strain, age and gender on cognitive performance in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Spatial memory in aged rats: population heterogeneity and effect of levocarnitine acetyl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Effect of acetyl-l-carnitine chronic treatment on discrimination models in aged rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Animal models of declining memory in the aged: short-term and spatial memory in the aged rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Behavioral effects of acetyl-l-carnitine in the male rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Active avoidance learning in old rats chronically treated with levocarnitine acetyl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Nutritional supplements to increase muscle mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Effects of oral creatine supplementation on maximal pedalling performance in older adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Alpha-lipoic acid in liver metabolism and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

alpha-Lipoic acid as a biological antioxidant

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Determination of oxidized and reduced lipoic acid using high-performance liquid chromatography and coulometric detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Neuroprotection by the metabolic antioxidant alpha-lipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Neuroprotective effects of alpha-lipoic acid and its enantiomers demonstrated in rodent models of focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Cellular and mitochondrial changes in glutamate-induced HT4 neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Neuroprotective effects of alpha-lipoic acid and its positively charged amide analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

A positively charged alpha-lipoic acid analogue with increased cellular uptake and more potent immunomodulatory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Alpha-lipoic acid as a new treatment option for Alzheimer [corrected] type dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Glutamate neurotoxicity and diseases of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

21 January 2018

Excitotoxic cell death

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

NMDA receptors activate the arachidonic acid cascade system in striatal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

NMDA-dependent superoxide production and neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Excitatory amino acid uptake and N-methyl-D-aspartate-mediated secretion in a neural cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

The regulation of reactive oxygen species production during programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Oxidative DNA damage and senescence of human diploid fibroblast cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

N-t-Butyl hydroxylamine is an antioxidant that reverses age-related changes in mitochondria in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

N-t-butyl hydroxylamine, a hydrolysis product of alpha-phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Systemic acetyl-L-carnitine elevates nigral levels of glutathione and GABA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

The distribution and role of carnitine in the mammalian brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Carnitine, carnitine acyltransferases, and rat brain function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Levels of carnitines in brain and other tissues of rats of different ages: effect of acetyl-L-carnitine administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Spatial memory and NGF levels in aged rats: natural variability and effects of acetyl-L-carnitine treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Age-dependent deficits in radial maze performance in the rat: effect of chronic treatment with acetyl-L-carnitine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Acetyl-1-carnitine. 1: Effects on mortality, pathology and sensory-motor performance in aging rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Differential effect of acetyl-l-carnitine on open field behavior in young and old rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Differential inhibition by hyperammonemia of the electron transport chain enzymes in synaptosomes and non-synaptic mitochondria in ornithine transcarbamylase-deficient spf-mice: restoration by acetyl-L-carnitine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Long-term acetyl-L-carnitine treatment in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Double-blind parallel design pilot study of acetyl levocarnitine in patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Clinical and neurochemical effects of acetyl-L-carnitine in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Acylcarnitine deficiency in chronic fatigue syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

High uptake of [2-11C]acetyl-L-carnitine into the brain: a PET study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Acetyl-L-carnitine enhances Na(+), K(+)-ATPase glutathione-S-transferase and multiple unit activity and reduces lipid peroxidation and lipofuscin concentration in aged rat brain regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

The effect of L-carnitine and acetyl-L-carnitine on the disappearance of DNA single-strand breaks in human peripheral blood lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Antiradical effects in L-propionyl carnitine protection of the heart against ischemia-reperfusion injury: the possible role of iron chelation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Protection of the ischemic diabetic heart by L-propionylcarnitine therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Developments of a water-maze procedure for studying spatial learning in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Timing and the control of variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

The effects of dietary restriction on mitochondrial dysfunction in aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Oxidative stress, caloric restriction, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Aging and oxidative stress: modulation by dietary restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Micronutrients prevent cancer and delay aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

A method for detecting abasic sites in living cells: age-dependent changes in base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

Free radical theory of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02090.X

10.1111/J.1749-6632.2002.TB02090.X

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference