(Q34629200)

English

The localization of FGFR3 mutations causing thanatophoric dysplasia type I differentially affects phosphorylation, processing and ubiquitylation of the receptor

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

The localization of FGFR3 mutations causing thanatophoric dysplasia type I differentially affects phosphorylation, processing and ubiquitylation of the receptor (English)

1 reference

Europe PubMed Central

3 August 2017

phosphorylation

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

thanatophoric dysplasia

1 reference

based on heuristic

inferred from title

author name string

Jacky Bonaventure

1

1 reference

Europe PubMed Central

3 August 2017

William C Horne

2

1 reference

Europe PubMed Central

3 August 2017

Roland Baron

3

1 reference

Europe PubMed Central

3 August 2017

language of work or name

0 references

publication date

17 May 2007

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

274

1 reference

Europe PubMed Central

3 August 2017

3078-3093

1 reference

Europe PubMed Central

3 August 2017

12

1 reference

Europe PubMed Central

3 August 2017

Cell signaling by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

FGFs, heparan sulfate and FGFRs: complex interactions essential for development

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Common and distinct elements in cellular signaling via EGF and FGF receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Cellular signaling by fibroblast growth factor receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Bad bones, absent smell, selfish testes: the pleiotropic consequences of human FGF receptor mutations

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Common mutations in the fibroblast growth factor receptor 3 (FGFR 3) gene account for achondroplasia, hypochondroplasia, and thanatophoric dwarfism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

The molecular and genetic basis of fibroblast growth factor receptor 3 disorders: the achondroplasia family of skeletal dysplasias, Muenke craniosynostosis, and Crouzon syndrome with acanthosis nigricans

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Stop codon FGFR3 mutations in thanatophoric dwarfism type 1.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Molecular, radiologic, and histopathologic correlations in thanatophoric dysplasia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

A novel skeletal dysplasia with developmental delay and acanthosis nigricans is caused by a Lys650Met mutation in the fibroblast growth factor receptor 3 gene

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Distinct missense mutations of the FGFR3 lys650 codon modulate receptor kinase activation and the severity of the skeletal dysplasia phenotype

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

The transmembrane mutation G380R in fibroblast growth factor receptor 3 uncouples ligand-mediated receptor activation from down-regulation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Effect of transmembrane and kinase domain mutations on fibroblast growth factor receptor 3 chimera signaling in PC12 cells. A model for the control of receptor tyrosine kinase activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

The thanatophoric dysplasia type II mutation hampers complete maturation of fibroblast growth factor receptor 3 (FGFR3), which activates signal transducer and activator of transcription 1 (STAT1) from the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

The kinase activity of fibroblast growth factor receptor 3 with activation loop mutations affects receptor trafficking and signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Sustained ERK1/2 but not STAT1 or 3 activation is required for thanatophoric dysplasia phenotypes in PC12 cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

K644E/M FGFR3 mutants activate Erk1/2 from the endoplasmic reticulum through FRS2 alpha and PLC gamma-independent pathways

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

FGF receptors ubiquitylation: dependence on tyrosine kinase activity and role in downregulation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Differential activation of cysteine-substitution mutants of fibroblast growth factor receptor 3 is determined by cysteine localization

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Brefeldin A: insights into the control of membrane traffic and organelle structure

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Preclinical studies of fibroblast growth factor receptor 3 as a therapeutic target in multiple myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Transforming property of TEL-FGFR3 mediated through PI3-K in a T-cell lymphoma that subsequently progressed to AML.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

The Cbl family proteins: ring leaders in regulation of cell signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteins

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Tyrosine phosphorylation regulates maturation of receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Recycling of golgi-resident glycosyltransferases through the ER reveals a novel pathway and provides an explanation for nocodazole-induced Golgi scattering

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Retrograde transport of Golgi-localized proteins to the ER.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Endocytosis and signaling: a relationship under development.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Protein regulation by monoubiquitin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Endocytic function of von Hippel-Lindau tumor suppressor protein regulates surface localization of fibroblast growth factor receptor 1 and cell motility

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Src kinase activity is essential for osteoclast function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Tyrosine phosphoproteomics of fibroblast growth factor signaling: a role for insulin receptor substrate-4.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Leucine zipper-mediated homodimerization of the adaptor protein c-Cbl. A role in c-Cbl's tyrosine phosphorylation and its association with epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05835.X

21 January 2018

Identifiers

10.1111/J.1742-4658.2007.05835.X

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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