(Q34665999)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044012%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

review article

1 reference

title

Gli and hedgehog in cancer: tumours, embryos and stem cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044012%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044012%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

Ariel Ruiz i Altaba

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044012%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Nadia Dahmane

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044012%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

language of work or name

English

0 references

publication date

1 May 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044012%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

published in

Nature Reviews Cancer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044012%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044012%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

361-372

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044012%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044012%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrc796

9 November 2019

exact match

0 references

cites work

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31 March 2020

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Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

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Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

31 March 2020

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

31 March 2020

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Comparative biological responses to human Sonic, Indian, and Desert hedgehog

31 March 2020

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The works of GLI and the power of hedgehog

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Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor

31 March 2020

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Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

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Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

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Distinct and regulated activities of human Gli proteins in Drosophila.

31 March 2020

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Gli/Zic factors pattern the neural plate by defining domains of cell differentiation.

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Sonic hedgehog promotes the survival of specific CNS neuron populations and protects these cells from toxic insult In vitro

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Inhibition of sonic hedgehog signaling in vivo results in craniofacial neural crest cell death

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Sonic hedgehog regulates epithelial proliferation and cell survival in the developing tooth germ

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Neuronal specification in the spinal cord: inductive signals and transcriptional codes

31 March 2020

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Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

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Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

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Wnt signals are targets and mediators of Gli function.

31 March 2020

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Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors

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Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells.

31 March 2020

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Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity

31 March 2020

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Patched1 interacts with cyclin B1 to regulate cell cycle progression

31 March 2020

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Sonic hedgehog opposes epithelial cell cycle arrest

31 March 2020

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Nevoid basal cell carcinoma syndrome

31 March 2020

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Human homolog of patched, a candidate gene for the basal cell nevus syndrome

31 March 2020

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Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

31 March 2020

1 reference

Altered neural cell fates and medulloblastoma in mouse patched mutants

31 March 2020

1 reference

Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

31 March 2020

1 reference

Basal cell carcinomas in mice overexpressing sonic hedgehog

31 March 2020

1 reference

Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog

31 March 2020

1 reference

Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice

31 March 2020

1 reference

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

31 March 2020

1 reference

Basal cell carcinomas in mice overexpressing Gli2 in skin

31 March 2020

1 reference

The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas

31 March 2020

1 reference

Activating Smoothened mutations in sporadic basal-cell carcinoma

31 March 2020

1 reference

Gli1 protein is expressed in basal cell carcinomas, outer root sheath keratinocytes and a subpopulation of mesenchymal cells in normal human skin

31 March 2020

1 reference

Activation of expression of hedgehog target genes in basal cell carcinomas

31 March 2020

1 reference

Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome

31 March 2020

1 reference

Monstrous attempts at adnexogenesis: regulating hair follicle progenitors through Sonic hedgehog signaling

31 March 2020

1 reference

Sonic hedgehog signaling is essential for hair development

31 March 2020

1 reference

Essential role for Sonic hedgehog during hair follicle morphogenesis

31 March 2020

1 reference

Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog

31 March 2020

1 reference

Involvement of follicular stem cells in forming not only the follicle but also the epidermis

31 March 2020

1 reference

At the roots of a never-ending cycle.

31 March 2020

1 reference

Cerebellar granule cell neurogenesis is regulated by cell-cell interactions in vitro.

31 March 2020

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Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma.

31 March 2020

1 reference

Prediction of central nervous system embryonal tumour outcome based on gene expression

31 March 2020

1 reference

Gliomagenesis: genetic alterations and mouse models

31 March 2020

1 reference

Malignant glioma: genetics and biology of a grave matter.

31 March 2020

1 reference

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

31 March 2020

1 reference

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

31 March 2020

1 reference

PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

31 March 2020

1 reference

Identification of an amplified, highly expressed gene in a human glioma

31 March 2020

1 reference

In situ hybridization with single-stranded RNA probes to demonstrate infrequently elevated gli mRNA and no increased ras mRNA levels in meningiomas and astrocytomas

31 March 2020

1 reference

A search for gli expression in tumors of the central nervous system

31 March 2020

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Teratogen-mediated inhibition of target tissue response to Shh signaling.

31 March 2020

1 reference

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

31 March 2020

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From fruitflies to mammals: mechanisms of signalling via the Sonic hedgehog pathway in lung development

31 March 2020

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Immunolocalization of sonic hedgehog (Shh) in developing mouse lung

31 March 2020

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Prostate development requires Sonic hedgehog expressed by the urogenital sinus epithelium

31 March 2020

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Molecular genetics of prostate cancer.

31 March 2020

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Involvement of PTCH gene in various noninflammatory cysts

31 March 2020

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Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice

31 March 2020

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Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt-1 transgenic mice by insertional activation of int-2/Fgf-3 and hst/Fgf-4.

31 March 2020

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Hedgehog signaling in mouse mammary gland development and neoplasia

31 March 2020

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31 March 2020

The Hallmarks of Cancer

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Mediation of Sonic hedgehog-induced expression of COUP-TFII by a protein phosphatase

31 March 2020

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The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A

31 March 2020

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Identification of sonic hedgehog-responsive genes using cDNA microarray

31 March 2020

1 reference

Epigenetic gene deregulation in cancer.

31 March 2020

1 reference

Stem cells, cancer, and cancer stem cells

31 March 2020

1 reference

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

31 March 2020

1 reference

Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation

31 March 2020

1 reference

Erythroid differentiation in vitro is blocked by cyclopamine, an inhibitor of hedgehog signaling

31 March 2020

1 reference

Identical mutations of the p53 tumor suppressor gene in the gliomatous and the sarcomatous components of gliosarcomas suggest a common origin from glial cells.

31 March 2020

1 reference

Genetic profile of gliosarcomas

31 March 2020

1 reference

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

31 March 2020

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Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors

31 March 2020

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

31 March 2020

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

31 March 2020

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A unified hypothesis on the lineage of neural stem cells.

31 March 2020

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Amphibian limb regeneration: rebuilding a complex structure

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Neuroepithelial stem cells from the embryonic spinal cord: isolation, characterization, and clonal analysis

31 March 2020

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Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

31 March 2020

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Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease

31 March 2020

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A role of PDGFRalpha in basal cell carcinoma proliferation

31 March 2020

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Dependence of autocrine growth factor stimulation in platelet-derived growth factor-B-induced mouse brain tumor cells

31 March 2020

1 reference

Treatment and prevention of rat glioblastoma by immunogenic C6 cells expressing antisense insulin-like growth factor I RNA.

31 March 2020

1 reference

The IGF/IGFBP system in CNS malignancy

31 March 2020

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Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma.

31 March 2020

1 reference

Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors

31 March 2020

1 reference

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

31 March 2020

1 reference

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

31 March 2020

1 reference

The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells

31 March 2020

1 reference

Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

31 March 2020

1 reference

Radial glial identity is promoted by Notch1 signaling in the murine forebrain

31 March 2020

1 reference

Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation.

31 March 2020

1 reference

The glial and mesenchymal elements of gliosarcomas share similar genetic alterations.

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Teratocarcinomas and other neoplasms as developmental defects in gene expression.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRC796

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044012%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 November 2019

0 references

1 reference