(Q34670390)

3 August 2017

Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia (English)

1 reference

3 August 2017

1 reference

lymphoblastic leukemia

1 reference

5

Robert Huether

1 reference

3 August 2017

Jordi Barretina Ginesta

object named as

Jordi Barretina

26

0 references

Charles G. Mullighan

object named as

Charles Mullighan

28

0 references

Levi A Garraway

31

object named as

Levi A Garraway

1 reference

3 August 2017

Jacob D Jaffe

1

1 reference

3 August 2017

Yan Wang

2

1 reference

3 August 2017

Ho Man Chan

3

1 reference

3 August 2017

Jinghui Zhang

4

1 reference

3 August 2017

Gregory V Kryukov

6

1 reference

3 August 2017

Hyo-eun C Bhang

7

1 reference

3 August 2017

Jordan E Taylor

8

1 reference

3 August 2017

Min Hu

9

1 reference

3 August 2017

Nathan P Englund

10

1 reference

3 August 2017

Feng Yan

11

1 reference

3 August 2017

Zhaofu Wang

12

1 reference

3 August 2017

E Robert McDonald

13

1 reference

3 August 2017

Lei Wei

14

1 reference

3 August 2017

Jing Ma

15

1 reference

3 August 2017

John Easton

16

1 reference

3 August 2017

Zhengtian Yu

17

1 reference

3 August 2017

Rosalie deBeaumount

18

1 reference

3 August 2017

Veronica Gibaja

19

1 reference

3 August 2017

Kavitha Venkatesan

20

1 reference

3 August 2017

Robert Schlegel

21

1 reference

3 August 2017

William R Sellers

22

1 reference

3 August 2017

Nicholas Keen

23

1 reference

3 August 2017

Jun Liu

24

1 reference

3 August 2017

Giordano Caponigro

25

1 reference

3 August 2017

Vesselina G Cooke

27

1 reference

3 August 2017

Steven A Carr

29

1 reference

3 August 2017

James R Downing

30

1 reference

3 August 2017

Frank Stegmeier

32

1 reference

3 August 2017

language of work or name

English

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publication date

29 September 2013

1 reference

3 August 2017

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3 August 2017

45

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3 August 2017

1386-1391

1 reference

3 August 2017

11

1 reference

https://scigraph.springernature.com/pub.10.1038/ng.2777

3 August 2017

0 references

cites work

Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Histone modifications and cancer: biomarkers of prognosis?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

The role of mutations in epigenetic regulators in myeloid malignancies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Quantitative assessment of chromatin immunoprecipitation grade antibodies directed against histone modifications reveals patterns of co-occurring marks on histone protein molecules

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Structural Chemistry of Human SET Domain Protein Methyltransferases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

CREST maps somatic structural variation in cancer genomes with base-pair resolution.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Global levels of histone modifications predict prognosis in different cancers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

The SWISS-MODEL Repository and associated resources

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Multiple-myeloma-related WHSC1/MMSET isoform RE-IIBP is a histone methyltransferase with transcriptional repression activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Histone modifications as markers of cancer prognosis: a cellular view.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Chemical derivatization of histones for facilitated analysis by mass spectrometry.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Detection of t(4;14)(p16.3;q32) chromosomal translocation in multiple myeloma by reverse transcription-polymerase chain reaction analysis of IGH-MMSET fusion transcripts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262138

Molecular biology. Genetic events that shape the cancer epigenome

7 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24076604

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mass spectrometric characterization of human histone H3: a bird's eye view

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24076604

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.2777

1 reference

3 August 2017

1 reference

3 August 2017

1 reference