(Q34741569)

4 August 2017

1 reference

title

Targeting glycosylation as a therapeutic approach (English)

1 reference

4 August 2017

1 reference

Frances M Platt

3

0 references

author name string

Raymond A Dwek

series ordinal

1

1 reference

4 August 2017

Terry D Butters

series ordinal

2

1 reference

4 August 2017

Nicole Zitzmann

series ordinal

4

1 reference

4 August 2017

1 January 2002

1 reference

Nature Reviews Drug Discovery

4 August 2017

1 reference

4 August 2017

1

1 reference

4 August 2017

65-75

1 reference

4 August 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1038/nrd708

4 August 2017

0 references

cites work

Conformation-independent binding of monoglucosylated ribonuclease B to calnexin

1 reference

Roles for glycosylation of cell surface receptors involved in cellular immune recognition

31 March 2020

1 reference

The C-type lectin superfamily in the immune system.

31 March 2020

1 reference

Congenital disorders of glycosylation: glycosylation defects in man and biological models for their study

31 March 2020

1 reference

Glycobiology: "towards understanding the function of sugars".

31 March 2020

1 reference

Glycoprotein glycosylation and cancer progression

31 March 2020

1 reference

Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG

31 March 2020

1 reference

A vital role for glycosphingolipid synthesis during development and differentiation

31 March 2020

1 reference

Cellular pathology of lysosomal storage disorders.

31 March 2020

1 reference

Amino-sugar glycosidase inhibitors: versatile tools for glycobiologists

31 March 2020

1 reference

Inhibition of Glycosphingolipid Biosynthesis: Application to Lysosomal Storage Disorders

31 March 2020

1 reference

Glycosylation inhibitors in biology and medicine

31 March 2020

1 reference

Long-term effectiveness of a new alpha-glucosidase inhibitor (BAY m1099-miglitol) in insulin-treated type 2 diabetes mellitus

31 March 2020

1 reference

Calnexin: a membrane-bound chaperone of the endoplasmic reticulum

31 March 2020

1 reference

Transient, lectin-like association of calreticulin with folding intermediates of cellular and viral glycoproteins

31 March 2020

1 reference

α-Glucosidase inhibitors as potential broad based anti-viral agents

31 March 2020

1 reference

Role of carbohydrate processing and calnexin binding in the folding and activity of the HN protein of Newcastle disease virus

31 March 2020

1 reference

Antiviral effect of N-butyldeoxynojirimycin against bovine viral diarrhea virus correlates with misfolding of E2 envelope proteins and impairment of their association into E1-E2 heterodimers

31 March 2020

1 reference

The effects of inhibitors of glucosidase I on the formation of Sindbis virus

31 March 2020

1 reference

Studies with inhibitors of oligosaccharide processing indicate a functional role for complex sugars in the transport and proteolysis of friend mink cell focus-inducing murine leukemia virus envelope proteins

31 March 2020

1 reference

Inhibition of HIV and SIV infectivity by blockade of α-glucosidase activity

31 March 2020

1 reference

Evidence that N-linked glycosylation is necessary for hepatitis B virus secretion

31 March 2020

1 reference

Study of the mechanism of antiviral action of iminosugar derivatives against bovine viral diarrhea virus

31 March 2020

1 reference

Secretion of human hepatitis B virus is inhibited by the imino sugar N-butyldeoxynojirimycin

31 March 2020

1 reference

Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion

31 March 2020

1 reference

Treatment of chronic hepadnavirus infection in a woodchuck animal model with an inhibitor of protein folding and trafficking.

31 March 2020

1 reference

Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: implications for the development of broad spectrum anti-hepatitis virus agents

31 March 2020

1 reference

N-butyldeoxygalactonojirimycin: a more selective inhibitor of glycosphingolipid biosynthesis than N-butyldeoxynojirimycin, in vitro and in vivo

31 March 2020

1 reference

Inhibition of hepatitis B virus DNA replication by imino sugars without the inhibition of the DNA polymerase: therapeutic implications

31 March 2020

1 reference

Prevalence of lysosomal storage disorders

31 March 2020

1 reference

Analogs of ceramide that inhibit glucocerebroside synthetase in mouse brain

31 March 2020

1 reference

Treatment of Gaucher disease with an enzyme inhibitor

31 March 2020

1 reference

New therapeutic prospects for the glycosphingolipid lysosomal storage diseases.

31 March 2020

1 reference

Modulation of cell-surface transferrin receptor by the imino sugar N-butyldeoxynojirimycin.

31 March 2020

1 reference

Mouse models of human lysosomal diseases.

31 March 2020

1 reference

Extensive Glycosphingolipid Depletion in the Liver and Lymphoid Organs of Mice Treated withN-Butyldeoxynojirimycin

31 March 2020

1 reference

Targeted disruption of the Hexa gene results in mice with biochemical and pathologic features of Tay-Sachs disease

31 March 2020

1 reference

Neuropathology of mice with targeted disruption of Hexa gene, a model of Tay-Sachs disease

31 March 2020

1 reference

Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism

31 March 2020

1 reference

Prevention of lysosomal storage in Tay-Sachs mice treated with N-butyldeoxynojirimycin

31 March 2020

1 reference

Delayed symptom onset and increased life expectancy in Sandhoff disease mice treated with N-butyldeoxynojirimycin.

31 March 2020

1 reference

Enhanced survival in Sandhoff disease mice receiving a combination of substrate deprivation therapy and bone marrow transplantation.

31 March 2020

1 reference

A genetic model of substrate deprivation therapy for a glycosphingolipid storage disorder

31 March 2020

1 reference

Critical role for glycosphingolipids in Niemann-Pick disease type C.

31 March 2020

1 reference

Alleviation of neuronal ganglioside storage does not improve the clinical course of the Niemann-Pick C disease mouse

31 March 2020

1 reference

Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis.

31 March 2020

1 reference

Substrate reduction therapy for glycosphingolipid storage disorders

31 March 2020

1 reference

6-0-butanoylcastanospermine (MDL 28,574) inhibits glycoprotein processing and the growth of HIVs

31 March 2020

1 reference

Antiretroviral activity of castanospermine and deoxynojirimycin, specific inhibitors of glycoprotein processing.

31 March 2020

1 reference

The effect of oral treatment with 6-O-butanoyl castanospermine (MDL 28,574) in the murine zosteriform model of HSV-1 infection

31 March 2020

1 reference

Antiviral activity and metabolism of the castanospermine derivative MDL 28,574, in cells infected with herpes simplex virus type 2.

31 March 2020

1 reference

Characterization of a human cytomegalovirus glycoprotein complex (gcI)

31 March 2020

1 reference

Loss of cytomegalovirus infectivity after treatment with castanospermine or related plant alkaloids correlates with aberrant glycoprotein synthesis

31 March 2020

1 reference

On the role of oligosaccharide trimming in the maturation of Sindbis and influenza virus

31 March 2020

1 reference

Glucose trimming and mannose trimming affect different phases of the maturation of Sindbis virus in infected BHK cells

31 March 2020

1 reference

The significance of carbohydrate trimming for the antigenicity of the Semliki Forest virus glycoprotein E2

31 March 2020

1 reference

Differences in antigenicity of E2 in Semliki Forest virus particles and in infected cells

31 March 2020

1 reference

The role of N-glycosylation in cell fusion induced by a vaccinia recombinant virus expressing both measles virus glycoproteins

31 March 2020

1 reference

Alpha-glucosidase inhibitors reduce dengue virus production by affecting the initial steps of virion morphogenesis in the endoplasmic reticulum

31 March 2020

1 reference

Post-translational processing of the glycoproteins of lymphocytic choriomeningitis virus

31 March 2020

1 reference

Biosynthesis and processing of the Autographa californica nuclear polyhedrosis virus gp64 protein

31 March 2020

1 reference

Involvement of endoplasmic reticulum chaperones in the folding of hepatitis C virus glycoproteins

31 March 2020

1 reference

7 January 2021

Posttranslational modifications distinguish the envelope glycoprotein of the immunodeficiency disease-inducing feline leukemia virus retrovirus

1 reference

7 January 2021

The alpha-glucosidase inhibitor N-butyldeoxynojirimycin inhibits human immunodeficiency virus entry at the level of post-CD4 binding

1 reference

7 January 2021

N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with impaired gp120 shedding and gp41 exposure

1 reference

7 January 2021

N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with changes in antibody recognition of the V1/V2 region of gp120

1 reference

7 January 2021

Identifiers

DOI

10.1038/NRD708

1 reference

Dimensions Publication ID

4 August 2017

0 references

1 reference