(Q34747762)

4 August 2017

1 reference

title

Measurement of absolute oxygen levels in cells and tissues using oxygen sensors and 2-nitroimidazole EF5. (English)

1 reference

4 August 2017

0 references

Cameron J Koch

1

1 reference

PubMed ID

12125356

4 August 2017

language of work or name

English

0 references

publication date

1 January 2002

1 reference

4 August 2017

Methods in Enzymology

1 reference

4 August 2017

352

1 reference

4 August 2017

3-31

1 reference

Hypoxia-mediated drugs for radiation and chemotherapy

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

The hypoxic tumor cell: a target for selective cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Late results of a trial of hyperbaric oxygen and radiotherapy in head and neck cancer: a rationale for hypoxic cell sensitizers?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Implantation of the tongue and floor of mouth--what factors really do contribute to necrosis?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Final report on the united states phase i clinical trial of the hypoxic cell radiosensitizer, misonidazole (RO-07-0582; NSC #261037)

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Clinical trials with hypoxic cell sensitizers: time to retrench or time to push forward?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Oxygen in human tumors: correlations between methods of measurement and response to therapy. Summary of a workshop held November 19-20, 1992, at the National Cancer Institute, Bethesda, Maryland.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Pretreatment oxygenation profiles of human soft tissue sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Oxygen tension distributions are sufficient to explain the local response of human breast tumors treated with radiation alone

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Direct measurement of pO2 distribution and bioreductive enzymes in human malignant brain tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Oxygenation predicts radiation response and survival in patients with cervix cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Oxygen tension in human tumors: in vivo mapping using CT-guided probes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Correlations between 31P-NMR spectroscopy and tissue O2 tension measurements in a murine fibrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Heterogeneous oxygenation of rectal carcinomas in humans: a critical parameter for preoperative irradiation?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Permanent anatomic closure of the ductus arteriosus in newborn baboons: the roles of postnatal constriction, hypoxia, and gestation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Factors Affecting the Oxygen Tension around Cells Growing in Plastic Petri Dishes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

The release of oxygen from polystyrene Petri dishes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

A thin-film culturing technique allowing rapid gas-liquid equilibration (6 sec) with no toxicity to mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Oxygen effects in radiobiology

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Calibration of Oxygen-Dependent Quenching of the Phosphorescence of Pd-meso-tetra (4-Carboxyphenyl) Porphine: A Phosphor with General Application for Measuring Oxygen Concentration in Biological Systems

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Measurement of low levels of oxygen and their effect on respiration in cell suspensions maintained in an open system.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Influence of glucose and oxygen supply conditions on the oxygenation of multicellular spheroids

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Radiolytic reduction of protein and nonprotein disulfides in the presence of formate: a chain reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Importance of thiols in the reductive binding of 2-nitroimidazoles to macromolecules

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Binding of misonidazole to V79 spheroids and fragments of Dunning rat prostatic and human colon carcinomas in vitro: diffusion of oxygen and reactive metabolites

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Changes in misonidazole binding with hypoxic fraction in mouse tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Microscopic distribution of misonidazole in mouse tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Retention of misonidazole in normal and malignant tissues: interplay of hypoxia and reductases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Is misonidazole binding to mouse tissues a measure of cellular pO2?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

The labelling of EMT-6 tumours in BALB/C mice with 14C-misonidazole

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

A novel technique for measuring human tissue pO2 at the cellular level

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Flow cytometric evaluation of hypoxic cells in solid experimental tumours using fluorescence immunodetection

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Pharmacokinetics and binding of the bioreductive probe for hypoxia, NITP: effect of route of administration

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Oxygen dependence of cellular uptake of EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)a cet amide] : analysis of drug adducts by fluorescent antibodies vs bound radioactivity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Detection of individual hypoxic cells in multicellular spheroids by flow cytometry using the 2-nitroimidazole, EF5, and monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Direct relationship between radiobiological hypoxia in tumors and monoclonal antibody detection of EF5 cellular adducts

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Tissue hypoxia inhibits prostaglandin and nitric oxide production and prevents ductus arteriosus reopening

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Detection of hypoxic cells with the 2-nitroimidazole, EF5, correlates with early redox changes in rat brain after perinatal hypoxia-ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Cyanine dye labeling reagents--carboxymethylindocyanine succinimidyl esters

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Initial results of a phase I trial of continuous infusion SR 2508 (etanidazole): a radiation therapy oncology group study.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Proliferation and hypoxia in human squamous cell carcinoma of the cervix: first report of combined immunohistochemical assays

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

A clinical phase I toxicity study of Ro 03-8799: plasma, urine, tumour and normal brain pharmacokinetics.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

The radiosensitizer Ro 03-8799 and the concentrations which may be achieved in human tumours: a preliminary study

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

The reversible N-oxidation of the nitroimidazole radiosensitizer Ro 03-8799

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Pharmacokinetics of EF5 [2-(2-nitro-1-H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide] in human patients: implications for hypoxia measurements in vivo by 2-nitroimidazoles.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Hypoxia in human intraperitoneal and extremity sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Chondrocytes in the endochondral growth cartilage are not hypoxic

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Measuring hypoxia and predicting tumor radioresistance with nuclear medicine assays

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Hypoxic fractions of solid tumors: experimental techniques, methods of analysis, and a survey of existing data

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

Misonidazole combined with split-course radiotherapy in the treatment of invasive carcinoma of larynx and pharynx: report from the DAHANCA 2 study

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2952003-6

7 January 2021

10.1016/S0076-6879(02)52003-6

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12125356