(Q34752184)

25453101

4 August 2017

title

Stoichiometry and assembly of mTOR complexes revealed by single-molecule pulldown (English)

1 reference

4 August 2017

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453101%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

6

Taekjip Ha

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453101%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

3

Vasudha Aggarwal

1 reference

10 June 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453101%20AND%20SRC:MED&resulttype=core&format=json

2

Edwin Arauz

1 reference

10 June 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453101%20AND%20SRC:MED&resulttype=core&format=json

Ankur Jain

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453101%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jie Chen

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453101%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

English

0 references

publication date

1 December 2014

1 reference

25453101

Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453101%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453101%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453101%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

17833-17838

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453101%20AND%20SRC:MED&resulttype=core&format=json

mTOR kinase structure, mechanism and regulation

10 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Association of Argonaute proteins and microRNAs can occur after cell lysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

mTOR signaling in growth control and disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Single-molecule pull-down for studying protein interactions.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Phosphatidic acid activates mammalian target of rapamycin complex 1 (mTORC1) kinase by displacing FK506 binding protein 38 (FKBP38) and exerting an allosteric effect

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Probing cellular protein complexes using single-molecule pull-down

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Steady-state kinetic and inhibition studies of the mammalian target of rapamycin (mTOR) kinase domain and mTOR complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Structure of the human mTOR complex I and its implications for rapamycin inhibition.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

mTOR signaling at a glance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

A complex interplay between Akt, TSC2 and the two mTOR complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Rules of engagement for NMDA receptor subunits

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Subunit counting in membrane-bound proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Drosophila target of rapamycin kinase functions as a multimer.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

ATRIP oligomerization is required for ATR-dependent checkpoint signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Molecular organization of target of rapamycin complex 2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Dissociation of raptor from mTOR is a mechanism of rapamycin-induced inhibition of mTOR function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Structural symmetry and protein function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273350

Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1419425111

DySCo: quantitating associations of membrane proteins using two-color single-molecule tracking.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1419425111

Three-Dimensional Structure of the Human DNA-PKcs/Ku70/Ku80 Complex Assembled on DNA and Its Implications for DNA DSB Repair

21 January 2018

2 references

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1419425111

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/25453101

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1419425111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453101%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453101%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

25453101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453101%20AND%20SRC:MED&resulttype=core&format=json