(Q34770507)

4 August 2017

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title

DNA methylation and gene silencing in cancer: which is the guilty party? (English)

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4 August 2017

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1

Susan J Clark

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4 August 2017

John Melki

2

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PubMed ID

12154400

4 August 2017

language of work or name

English

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publication date

1 August 2002

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4 August 2017

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4 August 2017

21

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4 August 2017

5380-5387

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4 August 2017

35

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205598

4 August 2017

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cites work

Differential methylation of human LINE-1 retrotransposons in malignant cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Number of CpG islands and genes in human and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

DNA hypermethylation in tumorigenesis: epigenetics joins genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Creation of genomic methylation patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

The essentials of DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

CpG-rich islands and the function of DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Methylation-induced repression--belts, braces, and chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Sp1 elements protect a CpG island from de novo methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Demethylase activity is directed by histone acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

DNA hypomethylation leads to elevated mutation rates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

CpG islands in vertebrate genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Methylation-specific oligonucleotide microarray: a new potential for high-throughput methylation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

The DNA methylation paradox

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Cancer epigenetics comes of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

The RNA moiety of chick embryo 5-methylcytosine- DNA glycosylase targets DNA demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

How does DNA methylation repress transcription?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Suppression of intestinal neoplasia by DNA hypomethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Histone H3 lysine 9 methylation occurs rapidly at the onset of random X chromosome inactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Changes in DNA methylation during mouse embryonic development in relation to X-chromosome activity and imprinting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Epigenetic inheritance at the agouti locus in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

In vivo footprint and methylation analysis by PCR-aided genomic sequencing: comparison of active and inactive X chromosomal DNA at the CpG island and promoter of human PGK-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Epigenetic reprogramming in mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

X inactivation, differentiation, and DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

A CpG-rich RNA and an RNA helicase tightly associated with the DNA demethylation complex are present mainly in dividing chick embryo cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Undermethylation of specific LINE-1 sequences in human cells producing a LINE-1-encoded protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Bisulfite sequencing in preimplantation embryos: DNA methylation profile of the upstream region of the mouse imprinted H19 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

DNA methylation profile of the mouse skeletal alpha-actin promoter during development and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Cytosine methylation and the ecology of intragenomic parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Demethylation of the zygotic paternal genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

Pacing approaches to the patient with a univentricular heart and the factors associated with choice of pacing site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

7 January 2021

Chemistry. How are alkynes scrambled?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

7 January 2021

Increased cytosine DNA-methyltransferase activity during colon cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

7 January 2021

Increased DNA methyltransferase expression in leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

7 January 2021

Detailed methylation analysis of the glutathione S-transferase pi (GSTP1) gene in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

7 January 2021

A distinct sequence (ATAAA)n separates methylated and unmethylated domains at the 5'-end of the GSTP1 CpG island

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

7 January 2021

DNA methylation and specific protein-DNA interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

7 January 2021

Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205598

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205598

1 reference

PubMed ID

12154400

Dimensions Publication ID

4 August 2017

0 references

1 reference

PubMed ID

12154400