(Q34808441)

English

A strategy for systemic delivery of the oncolytic herpes virus HSV1716: redirected tropism by antibody-binding sites incorporated on the virion surface as a glycoprotein D fusion protein

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

A strategy for systemic delivery of the oncolytic herpes virus HSV1716: redirected tropism by antibody-binding sites incorporated on the virion surface as a glycoprotein D fusion protein (English)

1 reference

Europe PubMed Central

4 August 2017

oncolytic virus

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

J Conner

1

1 reference

Europe PubMed Central

4 August 2017

L Braidwood

2

1 reference

Europe PubMed Central

4 August 2017

S M Brown

3

1 reference

Europe PubMed Central

4 August 2017

publication date

14 August 2008

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

15

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Europe PubMed Central

4 August 2017

1579-1592

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Europe PubMed Central

4 August 2017

24

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Europe PubMed Central

4 August 2017

https://scigraph.springernature.com/pub.10.1038/gt.2008.121

0 references

Oncolytic viral therapies - the clinical experience

1 reference

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Herpes simplex virus type 1 deletion variants 1714 and 1716 pinpoint neurovirulence-related sequences in Glasgow strain 17+ between immediate early gene 1 and the 'a' sequence

1 reference

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Cell type and cell state determine differential in vitro growth of non-neurovirulent ICP34.5-negative herpes simplex virus types 1 and 2.

1 reference

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Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma

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HSV1716 injection into the brain adjacent to tumour following surgical resection of high-grade glioma: safety data and long-term survival

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Intralesional injection of herpes simplex virus 1716 in metastatic melanoma

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Potential for efficacy of the oncolytic Herpes simplex virus 1716 in patients with oral squamous cell carcinoma

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Future prospects for oncolytic therapy

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Ligand-directed targeting of genes to the site of disease

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Expression of a functional single chain antibody on the surface of extracellular enveloped vaccinia virus as a step towards selective tumour cell targeting

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Efficient retroviral vector targeting of carcinoembryonic antigen-positive tumors

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Improved gene transfer selectivity to hepatocarcinoma cells by retrovirus vector displaying single-chain variable fragment antibody against c-Met

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Cell type-specific targeting with sindbis pseudotyped lentiviral vectors displaying anti-CCR5 single-chain antibodies

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An oncolytic measles virus engineered to enter cells through the CD20 antigen

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Oncolytic measles viruses displaying a single-chain antibody against CD38, a myeloma cell marker.

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The 'adenobody' approach to viral targeting: specific and enhanced adenoviral gene delivery

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Targeting of adenoviral vectors through a bispecific single-chain antibody

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Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105).

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Coxsackievirus-adenovirus receptor genetically fused to anti-human CD40 scFv enhances adenoviral transduction of dendritic cells

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Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors.

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Retargeting of adenoviral infection to melanoma: Combining genetic ablation of native tropism with a recombinant bispecific single‐chain diabody (scDb) adapter that binds to fiber knob and HMWMAA

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Mesothelin-mediated targeting of adenoviral vectors for ovarian cancer gene therapy

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Engineered herpes simplex virus 1 is dependent on IL13Ralpha 2 receptor for cell entry and independent of glycoprotein D receptor interaction

1 reference

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Characterization of a recombinant herpes simplex virus 1 designed to enter cells via the IL13Ralpha2 receptor of malignant glioma cells

1 reference

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Specific targeted binding of herpes simplex virus type 1 to hepatocytes via the human hepatitis B virus preS1 peptide.

1 reference

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Vector integration: location, location, location

1 reference

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HSV-1 virions engineered for specific binding to cell surface receptors

1 reference

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Herpes simplex virus targeting to the EGF receptor by a gD-specific soluble bridging molecule

1 reference

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A herpes simplex virus recombinant that exhibits a single-chain antibody to HER2/neu enters cells through the mammary tumor receptor, independently of the gD receptors

1 reference

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Herpesvirus entry: an update

1 reference

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Herpes simplex virus: receptors and ligands for cell entry

1 reference

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Entry of herpes simplex virus type 1 into primary sensory neurons in vitro is mediated by Nectin-1/HveC

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Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family

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Herpes simplex virus type 1 strain HSV1716 grown in baby hamster kidney cells has altered tropism for nonpermissive Chinese hamster ovary cells compared to HSV1716 grown in vero cells

1 reference

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21 January 2018

The soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entry

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.121

21 January 2018

Herpes simplex virus type 1 ribonucleotide reductase large subunit: regions of the protein essential for subunit interaction and dimerization

1 reference

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Oncolytic viruses

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The herpes simplex virus (HSV) protein ICP34.5 is a virion component that forms a DNA-binding complex with proliferating cell nuclear antigen and HSV replication proteins

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.121

7 January 2021

based on heuristic

inferred from DOI database lookup

The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle study

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.121

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted infection of human cells via major histocompatibility complex class I molecules by Moloney murine leukemia virus-derived viruses displaying single-chain antibody fragment-envelope fusion proteins.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Recombinant herpes simplex virus type 1 engineered for targeted binding to erythropoietin receptor-bearing cells.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The ectodomain of a novel member of the immunoglobulin subfamily related to the poliovirus receptor has the attributes of a bona fide receptor for herpes simplex virus types 1 and 2 in human cells

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.121

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcription from the gene encoding the herpesvirus entry receptor nectin-1 (HveC) in nervous tissue of adult mouse

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.121

7 January 2021

based on heuristic

inferred from DOI database lookup

HveC (nectin-1) is expressed at high levels in sensory neurons, but not in motor neurons, of the rat peripheral nervous system

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.121

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/GT.2008.121

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

ResearchGate publication ID

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