(Q34810420)

4 August 2017

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title

Strategies for MMP inhibition in cancer: innovations for the post-trial era. (English)

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4 August 2017

2

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4 August 2017

Christopher Mark Overall

series ordinal

1

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PubMed ID

12209155

4 August 2017

language of work or name

English

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publication date

1 September 2002

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4 August 2017

Nature Reviews Cancer

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4 August 2017

2

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4 August 2017

657-672

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4 August 2017

9

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https://scigraph.springernature.com/pub.10.1038/nrc884

4 August 2017

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MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells

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Membrane type 1 matrix metalloproteinase regulates cellular invasiveness and survival in cutaneous epidermal cells

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Matrix metalloproteinases as therapeutic targets in arthritic diseases: bull's-eye or missing the mark?

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31 March 2020

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31 March 2020

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31 March 2020

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Malolactomycin D, a potent inhibitor of transcription controlled by the Ras responsive element, inhibits Ras-mediated transformation activity with suppression of MMP-1 and MMP-9 in NIH3T3 cells

31 March 2020

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AP-1--glucocorticoid receptor crosstalk taken to a higher level

31 March 2020

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31 March 2020

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31 March 2020

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Non-steroidal anti-inflammatory drugs inhibit matrix metalloproteinase-2 expression via repression of transcription in lung cancer cells

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment

31 March 2020

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Matrilysin in early stage intestinal tumorigenesis

31 March 2020

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Low plasma levels of matrix metalloproteinase 9 permit increased tumor angiogenesis.

31 March 2020

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Stimulation of matrix metalloproteinase-9 expression in human fibrosarcoma cells by synthetic matrix metalloproteinase inhibitors

31 March 2020

1 reference

Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergistically with synthetic matrix metalloproteinase (MMP) inhibitors but not with TIMP-4 to enhance the (Membrane type 1)-MMP-dependent activation of pro-MMP-2.

31 March 2020

1 reference

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31 March 2020

1 reference

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1

31 March 2020

1 reference

Structural properties of matrix metalloproteinases

31 March 2020

1 reference

Determination of protease cleavage site motifs using mixture-based oriented peptide libraries

31 March 2020

1 reference

Tumor targeting with a selective gelatinase inhibitor

31 March 2020

1 reference

Design, synthesis, and characterization of potent, slow-binding inhibitors that are selective for gelatinases

31 March 2020

1 reference

Tumor gelatinases and invasion inhibited by the green tea flavanol epigallocatechin-3-gallate

31 March 2020

1 reference

Neovastat, a naturally occurring multifunctional antiangiogenic drug, in phase III clinical trials

31 March 2020

1 reference

Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3.

31 March 2020

1 reference

cDNA cloning of the murine Pex gene implicated in X-linked hypophosphatemia and evidence for expression in bone

31 March 2020

1 reference

Suppression of angiogenesis by lentiviral delivery of PEX, a noncatalytic fragment of matrix metalloproteinase 2.

31 March 2020

1 reference

Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin C domain. The ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits cell invasion by disrupting native type I collagen cleavage.

31 March 2020

1 reference

Selective transduction of protease-rich tumors by matrix-metalloproteinase-targeted retroviral vectors

31 March 2020

1 reference

Interleukin-2-collagen chimeric protein which liberates interleukin-2 upon collagenolysis

31 March 2020

1 reference

Scaling down imaging: molecular mapping of cancer in mice

31 March 2020

1 reference

The promise and peril of surrogate end points in cancer research

31 March 2020

1 reference

Collagenolytic activity in amphibian tissues: a tissue culture assay

31 March 2020

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Punctin, a novel ADAMTS-like molecule, ADAMTSL-1, in extracellular matrix

31 March 2020

1 reference

Membrane-type matrix metalloproteinases

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Clinical studies with matrix metalloproteinase inhibitors

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRC884

1 reference

PubMed ID

12209155

Dimensions Publication ID

4 August 2017

0 references

1 reference

PubMed ID

12209155