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Function and regulation of the Mediator complex
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
21330129
retrieved
5 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Function and regulation of the Mediator complex
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
21330129
retrieved
5 August 2017
author
Joan W. Conaway
object named as
Joan Weliky Conaway
series ordinal
2
0 references
author name string
Ronald C Conaway
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
21330129
retrieved
5 August 2017
publication date
15 February 2011
1 reference
stated in
Europe PubMed Central
PubMed ID
21330129
retrieved
5 August 2017
published in
Current Opinion in Genetics & Development
1 reference
stated in
Europe PubMed Central
PubMed ID
21330129
retrieved
5 August 2017
volume
21
1 reference
stated in
Europe PubMed Central
PubMed ID
21330129
retrieved
5 August 2017
page(s)
225-230
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stated in
Europe PubMed Central
PubMed ID
21330129
retrieved
5 August 2017
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
21330129
retrieved
5 August 2017
cites work
Mediator and cohesin connect gene expression and chromatin architecture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Differential roles of transcriptional mediator subunits in regulation of multidrug resistance gene expression in Saccharomyces cerevisiae.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
A genome-wide RNA interference screen identifies a differential role of the mediator CDK8 module subunits for GATA/ RUNX-activated transcription in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
The human Mediator complex: a versatile, genome-wide regulator of transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Cyclin-dependent kinase 8 positively cooperates with Mediator to promote thyroid hormone receptor-dependent transcriptional activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Mediator head module structure and functional interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
CDK8 is a positive regulator of transcriptional elongation within the serum response network
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Mediator complex association with constitutively transcribed genes in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Complexity in transcription control at the activation domain-mediator interface
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Mediator structural conservation and implications for the regulation mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Mediator subunit Gal11p/MED15 is required for fatty acid-dependent gene activation by yeast transcription factor Oaf1p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Role for Med12 in regulation of Nanog and Nanog target genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
The Mediator subunit MDT-15 confers metabolic adaptation to ingested material
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
CDK8 is a stimulus-specific positive coregulator of p53 target genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Genome-wide location of the coactivator mediator: Binding without activation and transient Cdk8 interaction on DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
MED14 and MED1 differentially regulate target-specific gene activation by the glucocorticoid receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Dynamic regulation of pol II transcription by the mammalian Mediator complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
The mammalian Mediator complex and its role in transcriptional regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Ras induces mediator complex exchange on C/EBP beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Mediator influences Schizosaccharomyces pombe RNA polymerase II-dependent transcription in vitro.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
A component of the ARC/Mediator complex required for TGF beta/Nodal signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Structure, function, and activator-induced conformations of the CRSP coactivator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Novel critical role of a human Mediator complex for basal RNA polymerase II transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
The TRAP/SMCC/Mediator complex and thyroid hormone receptor function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Structural organization of yeast and mammalian mediator complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
TFIIH is negatively regulated by cdk8-containing mediator complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Mediator of Transcriptional Regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
Dissecting the regulatory circuitry of a eukaryotic genome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
General requirement for RNA polymerase II holoenzymes in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
8 July 2018
A canonical promoter organization of the transcription machinery and its regulators in the Saccharomyces genome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
26 October 2018
Head module control of mediator interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086004
retrieved
26 October 2018
The VP16 activation domain establishes an active mediator lacking CDK8 in vivo
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21330129
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Purification of a plant mediator from Arabidopsis thaliana identifies PFT1 as the Med25 subunit
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21330129
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21330129
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.GDE.2011.01.013
1 reference
stated in
Europe PubMed Central
PubMed ID
21330129
retrieved
5 August 2017
PMCID
3086004
1 reference
stated in
Europe PubMed Central
PubMed ID
21330129
retrieved
5 August 2017
PubMed ID
21330129
1 reference
stated in
Europe PubMed Central
PubMed ID
21330129
retrieved
5 August 2017
ResearchGate publication ID
49844532
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