(Q34981948)

5 August 2017

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title

Regulation and chance in the ontogeny of B and T cell antigen receptor repertoires (English)

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5 August 2017

Michael Zemlin

1

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author name string

Robert L Schelonka

series ordinal

2

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5 August 2017

Karl Bauer

series ordinal

3

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5 August 2017

Harry W Schroeder

series ordinal

4

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5 August 2017

publication date

1 January 2002

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5 August 2017

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5 August 2017

volume

26

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5 August 2017

issue

1-3

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5 August 2017

page(s)

265-278

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Regulation of the antibody repertoire through control of HCDR3 diversity.

5 August 2017

cites work

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12 December 2020

VHDJH gene sequences and antigen reactivity of monoclonal antibodies produced by human B-1 cells: evidence for somatic selection.

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12 December 2020

Developmentally controlled expression of immunoglobulin VH genes

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12 December 2020

The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus

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12 December 2020

The structural basis of germline-encoded VH3 immunoglobulin binding to staphylococcal protein A

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12 December 2020

T cell receptor repertoire diversity and clonal expansion in human neonates.

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12 December 2020

Factors that influence formation of B cell repertoire

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12 December 2020

Structure and evolution of mammalian VH families

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12 December 2020

Antibody structure and the evolution of immunoglobulin V gene segments

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12 December 2020

Polymorphism and evolution of Igh-V gene families

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12 December 2020

Comparison of D, JH, and junctional diversity in the fetal, adult, and aged B cell repertoires

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12 December 2020

Mechanisms that generate human immunoglobulin diversity operate from the 8th week of gestation in fetal liver

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12 December 2020

Slow, programmed maturation of the immunoglobulin HCDR3 repertoire during the third trimester of fetal life

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12 December 2020

Polyreactive antigen-binding B cells are the predominant cell type in the newborn B cell repertoire

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12 December 2020

Identical V region amino acid sequences and segments of sequences in antibodies of different specificities. Relative contributions of VH and VL genes, minigenes, and complementarity-determining regions to binding of antibody-combining sites

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12 December 2020

Insertion of N regions into heavy-chain genes is correlated with expression of terminal deoxytransferase in B cells

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12 December 2020

Evolution of specific antigen recognition: size reduction and restricted length distribution of the CDRH3 regions in the rainbow trout

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12 December 2020

Use of monoclonal antibodies in a study of the development of T lymphocytes in the human fetus

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12 December 2020

Restricted utilization of germ-line VH3 genes and short diverse third complementarity-determining regions (CDR3) in human fetal B lymphocyte immunoglobulin heavy chain rearrangements

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12 December 2020

The ontogeny of diversification at the immunoglobulin heavy chain locus in Xenopus

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12 December 2020

Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction

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12 December 2020

High frequency of natural autoantibodies in normal newborn mice.

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12 December 2020

Non-random employment of V beta 6 and J beta gene elements and conserved amino acid usage profiles in CDR3 regions of human fetal and adult TCR beta chain rearrangements

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12 December 2020

Early restriction of the human antibody repertoire

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12 December 2020

Human Ig heavy chain CDR3 regions in adult bone marrow pre-B cells display an adult phenotype of diversity: evidence for structural selection of DH amino acid sequences.

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12 December 2020

Immunoglobulin VH clan and family identity predicts variable domain structure and may influence antigen binding

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12 December 2020

Non-stochastic utilization of Ig V region genes in unselected human peripheral B cells.

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12 December 2020

Somatic generation of antibody diversity

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12 December 2020

Two human neonatal IgM antibodies encoded by different variable-region genes bind the same linear peptide: evidence for a stereotyped repertoire of epitope recognition

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12 December 2020

IgM heavy chain complementarity-determining region 3 diversity is constrained by genetic and somatic mechanisms until two months after birth.

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12 December 2020

Ig D(H) gene segment transcription and rearrangement before surface expression of the pan-B-cell marker CD19 in normal human bone marrow.

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12 December 2020

Virgin and memory T cells have different requirements for activation via the CD2 molecule.

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12 December 2020

Molecular mechanisms governing reading frame choice of immunoglobulin diversity genes

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12 December 2020

The diversity of rearranged immunoglobulin heavy chain variable region genes in peripheral blood B cells of preterm infants is restricted by short third complementarity-determining regions but not by limited gene segment usage

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12 December 2020

Sequence of the human immunoglobulin diversity (D) segment locus: a systematic analysis provides no evidence for the use of DIR segments, inverted D segments, "minor" D segments or D-D recombination

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12 December 2020

Immunoglobulin V H 3 Gene Products: Natural Ligands for HIV gp120

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12 December 2020

Anatomy of the antibody molecule

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12 December 2020

Fetal response to antigenic stimulus. I. Plasmacellular and lymphoid reactions in the human fetus to intrauterine infection

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12 December 2020

Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines

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12 December 2020

Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes

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12 December 2020

Developmental biology of T cell receptors

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12 December 2020

Thymus-independent and thymus-dependent responses to polysaccharide antigens

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12 December 2020

Expression of the human immunoglobulin heavy chain VH6 gene element by fetal B lymphocytes

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12 December 2020

The human heavy chain Ig V region gene repertoire is biased at all stages of B cell ontogeny, including early pre-B cells.

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12 December 2020

Structural basis of T cell recognition

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12 December 2020

Immunophenotyping of blood lymphocytes in childhood. Reference values for lymphocyte subpopulations

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12 December 2020

Biased VH gene usage in early lineage human B cells: evidence for preferential Ig gene rearrangement in the absence of selection.

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12 December 2020

Diverse organization of immunoglobulin VH gene loci in a primitive vertebrate

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12 December 2020

Canonical structures for the hypervariable regions of immunoglobulins

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12 December 2020

Developmental regulation of the human antibody repertoire.

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12 December 2020

Biased utilization of DHQ52 and JH4 gene segments in a human Ig transgenic minilocus is independent of antigenic selection.

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12 December 2020

Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities

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12 December 2020

Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions.

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12 December 2020

Longitudinal survey of lymphocyte subpopulations in the first year of life.

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12 December 2020

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12 December 2020

Expression pattern of the most JH-proximal human VH gene segment (VH6) in the B cell and antibody repertoire suggests a role of VH6-encoded IgM antibodies in early ontogeny

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12 December 2020

Heavy-chain directed B-cell maturation: continuous clonal selection beginning at the pre-B cell stage

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12 December 2020

Human cord blood antibody repertoire. Mixed population of VH gene segments and CDR3 distribution in the expressed C alpha and C gamma repertoires

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12 December 2020

VH restriction among human cold agglutinins. The VH4-21 gene segment is required to encode anti-I and anti-i specificities.

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12 December 2020

Terminal deoxynucleotidyl transferase and repertoire development

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12 December 2020

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12 December 2020

Predominant V-region gene configurations in the human antibody response to Haemophilus influenzae capsule polysaccharide

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12 December 2020

Efficient immune responses in mice lacking N-region diversity

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12 December 2020

Developmental regulation of D beta reading frame and junctional diversity in T cell receptor-beta transcripts from human thymus

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12 December 2020

Identifiers

DOI

10.1385/IR:26:1-3:265

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Dimensions Publication ID

5 August 2017

1047423315

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