(Q34999563)

5 August 2017

title

Enhanced production of recombinant secretory proteins in Pichia pastoris by optimizing Kex2 P1' site (English)

1 reference

5 August 2017

Pichia pastoris

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Xiaoyan Hui

5

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Yu Wang

object named as

Yu Wang

9

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author name string

Song Yang

1

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5 August 2017

Ye Kuang

2

1 reference

5 August 2017

Hongbo Li

3

1 reference

5 August 2017

Yuehong Liu

4

1 reference

5 August 2017

Peng Li

6

1 reference

5 August 2017

Zhiwu Jiang

7

1 reference

5 August 2017

Yulai Zhou

8

1 reference

5 August 2017

Aimin Xu

10

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5 August 2017

Shiwu Li

11

1 reference

5 August 2017

Pentao Liu

12

1 reference

5 August 2017

Donghai Wu

13

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5 August 2017

language of work or name

English

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publication date

19 September 2013

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5 August 2017

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5 August 2017

volume

8

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5 August 2017

issue

9

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5 August 2017

page(s)

e75347

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Creative Commons Attribution 4.0 International

5 August 2017

copyright license

start time

19 September 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3777899/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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8 July 2018

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The HAC1 gene from Pichia pastoris: characterization and effect of its overexpression on the production of secreted, surface displayed and membrane proteins

8 July 2018

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Genome-scale analysis of library sorting (GALibSo): Isolation of secretion enhancing factors for recombinant protein production in Pichia pastoris

8 July 2018

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Genome, secretome and glucose transport highlight unique features of the protein production host Pichia pastoris.

8 July 2018

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8 July 2018

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Novel insights into the unfolded protein response using Pichia pastoris specific DNA microarrays.

8 July 2018

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Processing of predicted substrates of fungal Kex2 proteinases from Candida albicans, C. glabrata, Saccharomyces cerevisiae and Pichia pastoris

8 July 2018

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Promoter library designed for fine-tuned gene expression in Pichia pastoris

8 July 2018

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Regulation of hematopoietic stem cells by the steel factor/KIT signaling pathway

8 July 2018

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Expression of recombinant proteins in Pichia pastoris

8 July 2018

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Transcriptomics-based identification of novel factors enhancing heterologous protein secretion in yeasts.

8 July 2018

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Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions

8 July 2018

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Development, migration, and survival of mast cells

8 July 2018

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Operational strategies, monitoring and control of heterologous protein production in the methylotrophic yeast Pichia pastoris under different promoters: a review

8 July 2018

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Heterologous protein production using the Pichia pastoris expression system.

8 July 2018

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Signal transduction via the stem cell factor receptor/c-Kit

8 July 2018

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Reliable high-throughput screening with Pichia pastoris by limiting yeast cell death phenomena

8 July 2018

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The kindest cuts of all: crystal structures of Kex2 and furin reveal secrets of precursor processing

8 July 2018

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The role of Kit-ligand in melanocyte development and epidermal homeostasis

8 July 2018

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8 July 2018

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Production of recombinant proteins in fermenter cultures of the yeast Pichia pastoris

8 July 2018

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Role of c-kit in mammalian spermatogenesis

8 July 2018

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High-yield secretion of recombinant gelatins by Pichia pastoris

8 July 2018

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Quantitative assessment of enzyme specificity in vivo: P2 recognition by Kex2 protease defined in a genetic system

8 July 2018

1 reference

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Interplay between S1 and S4 subsites in Kex2 protease: Kex2 exhibits dual specificity for the P4 side chain.

8 July 2018

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Stem cell factor and hematopoiesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777899

Internally consistent libraries of fluorogenic substrates demonstrate that Kex2 protease specificity is generated by multiple mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777899

The role of c-Kit and its ligand, stem cell factor, in mast cell apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777899

Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777899

Enzymes required for yeast prohormone processing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777899

Intracellular targeting and structural conservation of a prohormone-processing endoprotease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777899

Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777899

Expression of the Saccharomyces cerevisiae Kex2p endoprotease in inset cells. Evidence for a carboxy-terminal autoprocessing event

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777899

Expression and function of c-kit in hemopoietic progenitor cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777899

The pro-region of the Kex2 endoprotease of Saccharomyces cerevisiae is removed by self-processing.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777899

Market watch: Sales of biologics to show robust growth through to 2013.

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075347

Transcriptional response of P. pastoris in fed-batch cultivations to Rhizopus oryzae lipase production reveals UPR induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075347

The effect of temperature on the proteome of recombinant Pichia pastoris.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075347

Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075347

Optimization of humanized IgGs in glycoengineered Pichia pastoris.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075347

An upstream activation sequence controls the expression of AOX1 gene in Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075347

Enhancement of protein secretion in Pichia pastoris by overexpression of protein disulfide isomerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075347

Engineering of Pichia pastoris for improved production of antibody fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075347

Rapid protein extraction fromSaccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075347

Selection conflicts, gene expression, and codon usage trends in yeast

21 January 2018

1 reference

12 December 2020

Role of amino acid sequences flanking dibasic cleavage sites in precursor proteolytic processing. The importance of the first residue C-terminal of the cleavage site

1 reference

12 December 2020

Production of monoclonal antibodies by glycoengineered Pichia pastoris

1 reference

12 December 2020

Fresh from the biologic pipeline-2009

1 reference

12 December 2020

Use of high-performance anion exchange chromatography with pulsed amperometric detection for O-glycan determination in yeast

1 reference

12 December 2020

Purification of recombinant human serum albumin efficient purification using STREAMLINE

1 reference

12 December 2020

Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells

1 reference

12 December 2020

Use of Pichia pastoris for expression of recombinant proteins

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0075347

Identifiers

DOI

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5 August 2017

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5 August 2017

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