(Q35022507)

5 August 2017

Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27 (English)

1 reference

5 August 2017

1 reference

parkinsonian syndrome

1 reference

16

Carlo M Croce

1 reference

5 August 2017

Francesca Pentimalli

4

0 references

George A. Calin

3

object named as

George A Calin

1 reference

5 August 2017

12

Giovanni Scambia

1 reference

5 August 2017

Rossano Cesari

1

1 reference

5 August 2017

Eric S Martin

2

1 reference

5 August 2017

Roberta Bichi

5

1 reference

5 August 2017

Holly McAdams

6

1 reference

5 August 2017

Francesco Trapasso

7

1 reference

5 August 2017

Alessandra Drusco

8

1 reference

5 August 2017

Masayoshi Shimizu

9

1 reference

5 August 2017

Valeria Masciullo

10

1 reference

5 August 2017

Giuseppina D'Andrilli

11

1 reference

5 August 2017

Maria Cristina Picchio

13

1 reference

5 August 2017

Hansjuerg Alder

14

1 reference

5 August 2017

Andrew K Godwin

15

1 reference

5 August 2017

language of work or name

English

0 references

publication date

28 April 2003

1 reference

Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

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5 August 2017

100

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5 August 2017

5956-5961

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5 August 2017

10

1 reference

describes a project that uses

5 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC156308/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Parc: a cytoplasmic anchor for p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

WWOX: a candidate tumor suppressor gene involved in multiple tumor types

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

The genomic structure and promoter region of the human parkin gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Parkin and Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

M6P/IGF2R is mutated in squamous cell carcinoma of the lung

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

DNA hypermethylation in tumorigenesis: epigenetics joins genetics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

8 July 2018

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Cancer-specific chromosome alterations in the constitutive fragile region FRA3B.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Cancer epigenetics comes of age

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Enhancement of PCR amplification yield and specificity using AmpliTaq Gold DNA polymerase.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Common fragile sites and cancer (review)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Sequence of the FRA3B common fragile region: implications for the mechanism of FHIT deletion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Definition of a commonly deleted region in ovarian cancers to a 300-kb segment of chromosome 6q27.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Early involvement of 6q in surface epithelial ovarian tumors.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Multiple regions of chromosome 6q affected by loss of heterozygosity in primary human breast carcinomas

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Antioncogenes and human cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Proximal 6q, a region showing allele loss in primary breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Induction of senescence and control of tumorigenicity in BK virus transformed mouse cells by human chromosome 6.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Cytogenetic and molecular analysis of 6q deletions in Burkitt's lymphoma cell lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

cDNA sequence of human apolipoprotein(a) is homologous to plasminogen

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Molecular cloning and characterization of a full-length cDNA clone for human plasminogen

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Tumorigenicity in human melanoma cell lines controlled by introduction of human chromosome 6.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Deletions involving two distinct regions of 6q in B-cell non-Hodgkin lymphoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156308

Patient with 13 Chromosome Deletion: Evidence That the Retinoblastoma Gene Is a Recessive Cancer Gene

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0931262100

The MDM2 RING-finger domain is required to promote p53 nuclear export

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0931262100

Abnormalities of the long arm of chromosome 6 in childhood acute lymphoblastic leukemia

21 January 2018

1 reference

12 December 2020

Allele loss on chromosome arm 6q and fine mapping of the region at 6q27 in epithelial ovarian cancer

1 reference

12 December 2020

Detailed deletion mapping with a refined physical map of 7q31 localizes a putative tumor suppressor gene for breast cancer in the region of MET

1 reference

12 December 2020

A novel 4 cM minimal deletion unit on chromosome 6q25.1-q25.2 associated with high grade invasive epithelial ovarian carcinomas

1 reference

12 December 2020

Physical map of the D6S149-D6S193 region on chromosome 6Q27 and its involvement in benign surface epithelial ovarian tumours

1 reference

12 December 2020

Common regions of deletion on chromosomes 5q, 6q, and 10q in renal cell carcinoma

1 reference

12 December 2020

Suppression of tumorigenicity of breast cancer cells by microcell-mediated chromosome transfer: studies on chromosomes 6 and 11

1 reference

12 December 2020

Tumor suppressor genes

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0931262100

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference