(Q35030852)

English

Peripheral nerve pathology, including aberrant Schwann cell differentiation, is ameliorated by doxycycline in a laminin-α2-deficient mouse model of congenital muscular dystrophy.

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21505075%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Peripheral nerve pathology, including aberrant Schwann cell differentiation, is ameliorated by doxycycline in a laminin-α2-deficient mouse model of congenital muscular dystrophy (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21505075%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

congenital disorder

0 references

1 reference

based on heuristic

inferred from title

0 references

cell differentiation

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21505075%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21505075%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Mary Lou Beermann

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21505075%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

publication date

19 April 2011

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21505075%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Human Molecular Genetics

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21505075%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

20

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21505075%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

13

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21505075%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

2662-2672

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21505075%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Transgenic overexpression of laminin alpha1 chain in laminin alpha2 chain-deficient mice rescues the disease throughout the lifespan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Limb-girdle and congenital muscular dystrophies: current diagnostics, management, and emerging technologies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Matrix metalloproteinase inhibition enhances the rate of nerve regeneration in vivo by promoting dedifferentiation and mitosis of supporting schwann cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Congenital muscular dystrophies: toward molecular therapeutic interventions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Laminin alters fyn regulatory mechanisms and promotes oligodendrocyte development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Ku70 regulates Bax-mediated pathogenesis in laminin-alpha2-deficient human muscle cells and mouse models of congenital muscular dystrophy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Developmental and pathogenic mechanisms of basement membrane assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Congenital muscular dystrophy. Part I: a review of phenotypical and diagnostic aspects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Pathology is alleviated by doxycycline in a laminin-alpha2-null model of congenital muscular dystrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Disruption of laminin in the peripheral nervous system impedes nonmyelinating Schwann cell development and impairs nociceptive sensory function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

The molecular machinery of myelin gene transcription in Schwann cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Combination therapy with interferon beta-1a and doxycycline in multiple sclerosis: an open-label trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Linker molecules between laminins and dystroglycan ameliorate laminin-alpha2-deficient muscular dystrophy at all disease stages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Comparison of doxycycline and minocycline in the inhibition of VEGF-induced smooth muscle cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Laminin alpha1 chain improves laminin alpha2 chain deficient peripheral neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

The role of apoptosis in neuromuscular diseases and prospects for anti-apoptosis therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Tetracyclines: nonantibiotic properties and their clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Schwann cell-specific ablation of laminin gamma1 causes apoptosis and prevents proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Doxycycline attenuates and delays toxicity of the oculopharyngeal muscular dystrophy mutation in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Coordinate control of axon defasciculation and myelination by laminin-2 and -8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Inhibition of apoptosis improves outcome in a model of congenital muscular dystrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

The congenital muscular dystrophies in 2004: a century of exciting progress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Laminin gamma1 is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerve

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Disruption of ErbB receptor signaling in adult non-myelinating Schwann cells causes progressive sensory loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Schwann cell myelination occurred without basal lamina formation in laminin alpha2 chain-null mutant (dy3K/dy3K) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Promyelinating Schwann cells express Tst-1/SCIP/Oct-6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Merosin-deficient congenital muscular dystrophy. Partial genetic correction in two mouse models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Examining potential drug therapies for muscular dystrophy utilising the dy/dy mouse: I. Clenbuterol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Three markers of adult non-myelin-forming Schwann cells, 217c(Ran-1), A5E3 and GFAP: development and regulation by neuron-Schwann cell interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Quantitative Ultrastructural Studies of the Axon-Schwann Cell Abnormality in Spinal Nerve Roots from Dystrophic Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Abnormalities in Schwann cell sheaths in spinal nerve roots of dystrophic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Abnormalities of the sciatic nerves of dystrophic mice, with reference to nerve counts and mean area of axons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

Development of the amyelinated lesion in the ventral root of the dystrophic mouse. Ultrastructural, quantitative and autoradiographic study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

8 July 2018

A single point mutation in the LN domain of LAMA2 causes muscular dystrophy and peripheral amyelination

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR168

21 January 2018

The Transcription Factors SCIP and Krox-20 Mark Distinct Stages and Cell Fates in Schwann Cell Differentiation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR168

21 January 2018

Laminin alpha2 chain-null mutant mice by targeted disruption of the Lama2 gene: a new model of merosin (laminin 2)-deficient congenital muscular dystrophy.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR168

21 January 2018

Laminin alpha1 chain reduces muscular dystrophy in laminin alpha2 chain deficient mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR168

21 January 2018

Proteasome inhibition improves the muscle of laminin α2 chain-deficient mice.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR168

21 January 2018

Complement 3 deficiency and oral prednisolone improve strength and prolong survival of laminin alpha2-deficient mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR168

21 January 2018

High protein diet has beneficial effects in murine muscular dystrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110004

25 October 2018

Laminin α2 deficiency and muscular dystrophy; genotype-phenotype correlation in mutant mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR168

21 January 2018

Effect of doxycycline on atherosclerosis: from bench to bedside

1 reference

https://pubmed.ncbi.nlm.nih.gov/21505075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schwann cell multiplication deficit in nerve roots of newborn dystrophic mice. A radioautographic and ultrastructural study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21505075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent multiplication of axon-associated cells in the spinal roots of dystrophic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21505075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative studies of the abnormal axon-Schwann cell relationship in the peripheral motor and sensory nerves of the dystrophic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/21505075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demyelinating peripheral neuropathy in merosin-deficient congenital muscular dystrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21505075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscle-specific BCL2 expression ameliorates muscle disease in laminin {alpha}2-deficient, but not in dystrophin-deficient, mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21505075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential sensitivity of skeletal and fusimotor neurons to Bcl-2-mediated apoptosis during neuromuscular development

1 reference

https://pubmed.ncbi.nlm.nih.gov/21505075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IGF-I treatment improves the functional properties of fast- and slow-twitch skeletal muscles from dystrophic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21505075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDR168

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21505075%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

release_6t4orzhvvrdkrghrvjxinjvogu

1 reference

https://api.fatcat.wiki/v0/release/6t4orzhvvrdkrghrvjxinjvogu

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21505075%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21505075%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q35030852&oldid=1842863377"