(Q35052515)

6 August 2017

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title

The role of VEGF in normal and neoplastic hematopoiesis (English)

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6 August 2017

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2

Napoleone Ferrara

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6 August 2017

Hans-Peter Gerber

1

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6 August 2017

14 December 2002

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Journal of Molecular Medicine

6 August 2017

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6 August 2017

81

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6 August 2017

20-31

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6 August 2017

1

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https://scigraph.springernature.com/pub.10.1007/s00109-002-0397-4

6 August 2017

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cites work

VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism

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https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Mechanism of autocrine stimulation in hematopoietic cells producing interleukin-3 after retrovirus-mediated gene transfer

21 January 2018

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Angiogenesis and bone growth

21 January 2018

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Molecular and biological properties of the vascular endothelial growth factor family of proteins

21 January 2018

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The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA.

21 January 2018

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The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF.

21 January 2018

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Isoforms of vascular endothelial growth factor act in a coordinate fashion To recruit and expand tumor vasculature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Molecular mechanisms of lymphangiogenesis in health and disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Vasculotropin/vascular endothelial growth factor induces differentiation in cultured osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Role of vascular endothelial growth factor in the regulation of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Conditional requirement for the Flk-1 receptor in the in vitro generation of early hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Structure and dual function of vascular endothelial growth factor receptor-1 (Flt-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Hematopoiesis: wandering progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Hematopoietic commitment during embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

KDR receptor: a key marker defining hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Enhanced inhibition of hepatitis B virus production by asialoglycoprotein receptor-directed interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Loss of placental growth factor protects mice against vascular permeability in pathological conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Placenta growth factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PlGF-1/VEGF heterodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Constitutive expression of the granulocyte-macrophage colony-stimulating factor gene in acute myeloblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Interleukin 1 as an autocrine growth factor for acute myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

The antiangiogenic protein kinase inhibitors SU5416 and SU6668 inhibit the SCF receptor (c-kit) in a human myeloid leukemia cell line and in acute myeloid leukemia blasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Stable remission after administration of the receptor tyrosine kinase inhibitor SU5416 in a patient with refractory acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Purified hematopoietic stem cells can differentiate into hepatocytes in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Bone marrow in polycythemia vera, chronic myelocytic leukemia, and myelofibrosis has an increased vascularity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Expression of FLT4 and its ligand VEGF-C in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Expression of the macrophage colony-stimulating factor and c-fms genes in human acute myeloblastic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Cellular proliferation and activation of NF kappa B are induced by autocrine production of tumor necrosis factor alpha in the human T lymphoma line HuT 78.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Lymphotoxin acts as an autocrine growth factor for Epstein-Barr virus-transformed B cells and differentiated Burkitt lymphoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Constituents of autocrine IL-6 loops in myeloma cell lines and their targeting for suppression of neoplastic growth by antibody strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-002-0397-4

Role of vascular endothelial growth factor (VEGF) and placenta-derived growth factor (PlGF) in regulating human haemopoietic cell growth

21 January 2018

1 reference

12 December 2020

Structure and expression of genes of GM-CSF and G-CSF in blast cells from patients with acute myeloblastic leukemia

1 reference

12 December 2020

Expression and secretion of vascular endothelial growth factor-A by cytokine-stimulated hematopoietic progenitor cells. Possible role in the hematopoietic microenvironment

1 reference

12 December 2020

Expression of functional interleukin-15 receptor and autocrine production of interleukin-15 as mechanisms of tumor propagation in multiple myeloma

1 reference

12 December 2020

Clinical relevance of vascular endothelial growth factor receptors 1 and 2 in acute myeloid leukaemia and myelodysplastic syndrome

1 reference

12 December 2020

Vascular endothelial growth factor(165) gene transfer augments circulating endothelial progenitor cells in human subjects

1 reference

12 December 2020

Stem cell plasticity in muscle and bone marrow

1 reference

12 December 2020

The vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK222584 inhibits growth and migration of multiple myeloma cells in the bone marrow microenvironment

1 reference

12 December 2020

Characterization of an interleukin-6-mediated autocrine growth loop in the human multiple myeloma cell line, U266.

1 reference

12 December 2020

Numerous growth factors, cytokines, and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner

1 reference

12 December 2020

Rapid turnover of the platelet-derived growth factor receptor in sis-transformed cells and reversal by suramin. Implications for the mechanism of autocrine transformation

1 reference

12 December 2020

B-lineage lymphoid blast crisis in juvenile chronic myelogenous leukemia: II. Interleukin-1-mediated autocrine growth regulation of the lymphoblasts.

1 reference

12 December 2020

Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies

1 reference

12 December 2020

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis

1 reference

12 December 2020

Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization

1 reference

12 December 2020

Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment

1 reference

12 December 2020

Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing MCL1 acting as an antiapoptotic factor.

1 reference

12 December 2020

VEGF145, a secreted vascular endothelial growth factor isoform that binds to extracellular matrix

1 reference

12 December 2020

Autostimulatory effects of IL-6 on excessive B cell differentiation in patients with systemic lupus erythematosus: analysis of IL-6 production and IL-6R expression

1 reference

12 December 2020

Overexpression of vascular endothelial growth factor (VEGF) and its cellular receptor KDR (VEGFR-2) in the bone marrow of patients with acute myeloid leukemia

1 reference

12 December 2020

Increased bone marrow vascularization in patients with acute myeloid leukaemia: a possible role for vascular endothelial growth factor

1 reference

12 December 2020

Flk-1 expression defines a population of early embryonic hematopoietic precursors.

1 reference

12 December 2020

Cellular vascular endothelial growth factor is a predictor of outcome in patients with acute myeloid leukemia.

1 reference

12 December 2020

Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice.

1 reference

12 December 2020

A high pretreatment serum vascular endothelial growth factor concentration is associated with poor outcome in non-Hodgkin's lymphoma

1 reference

12 December 2020

Insulin-like growth factor I is a growth and survival factor in human multiple myeloma cell lines.

1 reference

12 December 2020

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

1 reference

12 December 2020

Regulation of gene expression of M-, G-, GM-, and multi-CSF in normal and malignant hematopoietic cells

1 reference

12 December 2020

Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis

1 reference

12 December 2020

Vascular endothelial growth factor, a possible paracrine growth factor in human acute myeloid leukemia

1 reference

12 December 2020

Vascular endothelial growth factor-B-deficient mice display an atrial conduction defect

1 reference

12 December 2020

Role of Flk-1 in mouse hematopoietic stem cells

1 reference

12 December 2020

Prognostic significance of cellular vascular endothelial growth factor expression in chronic phase chronic myeloid leukemia

1 reference

12 December 2020

Autocrine secretion of GM-CSF in acute myeloblastic leukemia

1 reference

12 December 2020

Hematopoietic stem cell maintenance and differentiation are supported by embryonic aorta-gonad-mesonephros region-derived endothelium.

1 reference

12 December 2020

Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo

1 reference

12 December 2020

10.1007/S00109-002-0397-4

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12545246