(Q35056472)

6 August 2017

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title

Lymphoma- and leukemia-associated chromosomal translocations in healthy individuals (English)

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6 August 2017

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Siegfried Janz

1

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PubMed ID

12557221

6 August 2017

Michael Potter

series ordinal

2

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PubMed ID

12557221

6 August 2017

Charles S Rabkin

series ordinal

3

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6 August 2017

1 March 2003

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Genes, Chromosomes and Cancer

6 August 2017

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6 August 2017

36

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6 August 2017

211-223

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6 August 2017

3

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The NPM-ALK and the ATIC-ALK fusion genes can be detected in non-neoplastic cells

6 August 2017

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Cytogenetic changes in the progression of lymphoma

21 January 2018

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The frequency of illegitimate TCRbeta/gamma gene recombination in human lymphocytes: influence of age, environmental exposure and cytostatic treatment, and correlation with frequencies of t(14;18) and hprt mutation

21 January 2018

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Generation of immunoglobulin/c-myc recombinations in murine Peyer's patch follicles

21 January 2018

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The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

21 January 2018

1 reference

7 January 2021

Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector

1 reference

7 January 2021

The expression of ETV6/CBFA2 (TEL/AML1) is not sufficient for the transformation of hematopoietic cell lines in vitro or the induction of hematologic disease in vivo

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7 January 2021

Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

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7 January 2021

Leukemia- and lymphoma-associated genetic aberrations in healthy individuals

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7 January 2021

Occurrence of bcl-2 oncogene translocation with increased frequency in the peripheral blood of heavy smokers.

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7 January 2021

Frequencies of hprt(-) mutations and bcl-2 translocations in circulating human lymphocytes are correlated with United Kingdom sunlight records

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7 January 2021

Chromosome translocations in multiple myeloma

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7 January 2021

Molecular Cytogenetics of t(12;21)(p13;q22)

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7 January 2021

Translocations involving c-myc and c-myc function

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7 January 2021

Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse.

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7 January 2021

Rapid induction of B-cell lymphomas in mice carrying a human IgH/c-mycYAC

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7 January 2021

Exon scrambling of MLL transcripts occur commonly and mimic partial genomic duplication of the gene

1 reference

7 January 2021

Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development.

1 reference

7 January 2021

An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

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7 January 2021

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

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7 January 2021

Mll rearrangements in haematological malignancies: lessons from clinical and biological studies

1 reference

7 January 2021

Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.

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7 January 2021

BCL-2/JH rearrangements in circulating B cells of healthy blood donors and patients with nonmalignant diseases

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7 January 2021

Translocations involving anaplastic lymphoma kinase (ALK).

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7 January 2021

Breakage and fusion of the TEL (ETV6) gene in immature B lymphocytes induced by apoptogenic signals

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7 January 2021

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7 January 2021

Chronic neutrophilic leukemia (CNL): a clinical, pathologic and cytogenetic study

1 reference

7 January 2021

In utero rearrangements in the trithorax-related oncogene in infant leukaemias.

1 reference

7 January 2021

Fetal origins of the TEL-AML1 fusion gene in identical twins with leukemia

1 reference

7 January 2021

Quantification of t(14;18) in the lymphocytes of healthy adult humans as a possible biomarker for environmental exposures to carcinogens.

1 reference

7 January 2021

Quantification of hprt gene deletions mediated by illegitimate V(D)J recombination in peripheral blood cells of humans.

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7 January 2021

Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots

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7 January 2021

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

1 reference

7 January 2021

Spleen tyrosine kinase (Syk) deficiency in childhood pro-B cell acute lymphoblastic leukemia

1 reference

7 January 2021

Molecular genetics, natural history and the demise of childhood leukaemia

1 reference

7 January 2021

Non-Hodgkin's lymphoma and sunlight

1 reference

7 January 2021

Two critical hits for promyelocytic leukemia

1 reference

7 January 2021

In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications

1 reference

7 January 2021

Role of co-repressors in transcriptional repression mediated by the t(8;21), t(16;21), t(12;21), and inv(16) fusion proteins

1 reference

7 January 2021

Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

1 reference

7 January 2021

Variable numbers of BCR-ABL transcripts persist in CML patients who achieve complete cytogenetic remission with interferon-α

1 reference

7 January 2021

Detection of recombinations between c-myc and immunoglobulin switch alpha in murine plasma cell tumors and preneoplastic lesions by polymerase chain reaction

1 reference

7 January 2021

Deletional remodeling of c-myc-deregulating chromosomal translocations

1 reference

7 January 2021

Lymph nodes and Peyer's patches of IL-6 transgenic BALB/c mice harbor T(12;15) translocated plasma cells that contain illegitimate exchanges between the immunoglobulin heavy-chain mu locus and c-myc

1 reference

7 January 2021

Clonal diversification of primary BALB/c plasmacytomas harboring T(12;15) chromosomal translocations

1 reference

7 January 2021

Translocation remodeling in the primary BALB/c plasmacytoma TEPC 3610

1 reference

7 January 2021

IL-6 transgenic mouse model for extraosseous plasmacytoma

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7 January 2021

Burkitt lymphoma in the mouse.

1 reference

7 January 2021

Mechanisms of chromosomal translocations in B cell lymphomas

1 reference

7 January 2021

Incidence of AML1/ETO fusion transcripts in patients entered into the MRC AML trials. MRC Adult Leukaemia Working Party

1 reference

7 January 2021

AML1 and the AML1-ETO fusion protein in the pathogenesis of t(8;21) AML.

1 reference

7 January 2021

BCL2 translocation frequency rises with age in humans

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7 January 2021

Oncogenic transcription factors in the human acute leukemias

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7 January 2021

Reverse transcriptase template switching during reverse transcriptase-polymerase chain reaction: artificial generation of deletions in ribonucleotide reductase mRNA

1 reference

7 January 2021

Molecular tracking of leukemogenesis in a triplet pregnancy.

1 reference

7 January 2021

Detection of minimal residual disease in patients with AML1/ETO-associated acute myeloid leukemia using a novel quantitative reverse transcription polymerase chain reaction assay

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7 January 2021

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

1 reference

7 January 2021

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

1 reference

7 January 2021

AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

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7 January 2021

Chromosome translocations and covert leukemic clones are generated during normal fetal development

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7 January 2021

Differences in the molecular structure of c-myc-activating recombinations in murine plasmacytomas and precursor cells

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7 January 2021

Persistence of immunoglobulin heavy chain/c-myc recombination-positive lymphocyte clones in the blood of human immunodeficiency virus-infected homosexual men.

1 reference

7 January 2021

Copy-choice recombination by reverse transcriptases: reshuffling of genetic markers mediated by RNA chaperones

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7 January 2021

Retroviral recombination: what drives the switch?

1 reference

7 January 2021

Abnormalities of the ETV6 gene occur in the majority of patients with aberrations of the short arm of chromosome 12: a combined PCR and Southern blotting analysis.

1 reference

7 January 2021

Translocation t(14;18) in healthy individuals: preliminary study of its association with family history and agricultural exposure

1 reference

7 January 2021

In vivo analysis of the molecular genetics of acute promyelocytic leukemia

1 reference

7 January 2021

Detection of the t(14;18) chromosomal translocation by interphase cytogenetics with yeast-artificial-chromosome probes in follicular lymphoma and nonneoplastic lymphoproliferation

1 reference

7 January 2021

Mouse models of acute promyelocytic leukemia

1 reference

7 January 2021

Inhibition of plasmacytoma development in BALB/c mice by indomethacin

1 reference

7 January 2021

Plasmacytomagenesis in mice: model of neoplastic development dependent upon chromosomal translocations

1 reference

7 January 2021

PML-RARA fusion transcripts in irradiated and normal hematopoietic cells

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7 January 2021

Chromosomal translocations deregulating c-myc are associated with normal immune responses.

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7 January 2021

The role of PML in tumor suppression

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7 January 2021

A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination.

1 reference

7 January 2021

Persistence of dormant leukemic progenitors during interferon-induced remission in chronic myelogenous leukemia. Analysis by polymerase chain reaction of individual colonies

1 reference

7 January 2021

High frequency of leukemic clones in newborn screening blood samples of children with B-precursor acute lymphoblastic leukemia

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7 January 2021

Detection of the t(2;5)-associated NPM/ALK fusion cDNA in peripheral blood cells of healthy individuals

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7 January 2021

Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase

1 reference

7 January 2021

Microclustering of TEL-AML1 translocation breakpoints in childhood acute lymphoblastic leukemia

1 reference

7 January 2021

Prenatal origin of acute lymphoblastic leukaemia in children

1 reference

7 January 2021

In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia

1 reference

7 January 2021

Modeling Philadelphia chromosome positive leukemias

1 reference

7 January 2021

Low frequency of BCL-2/J(H) translocation in peripheral blood lymphocytes of healthy Japanese individuals

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7 January 2021

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

1 reference

7 January 2021

Identifiers

DOI

10.1002/GCC.10178

1 reference

6 August 2017

1 reference

PubMed ID

12557221