(Q35058551)

6 August 2017

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title

Innate immune sensing and its roots: the story of endotoxin (English)

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6 August 2017

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1

Bruce Beutler

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6 August 2017

Ernst Th Rietschel

2

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6 August 2017

1 February 2003

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Nature Reviews Immunology

6 August 2017

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6 August 2017

3

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6 August 2017

169-176

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6 August 2017

2

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Lipopolysaccharide endotoxins

6 August 2017

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Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities

31 March 2020

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Siderophore-mediated iron transport: crystal structure of FhuA with bound lipopolysaccharide

31 March 2020

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Isolation, structure elucidation, and synthesis of a macrophage stimulatory lipopeptide from Mycoplasma fermentans acting at picomolar concentration

31 March 2020

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Structure-function relationship of cytokine induction by lipoteichoic acid from Staphylococcus aureus

31 March 2020

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Interactions between bacterial CpG-DNA and TLR9 bridge innate and adaptive immunity

31 March 2020

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Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic respones to lipopolysaccharides

31 March 2020

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Genetic defect in responsiveness to the B cell mitogen lipopolysaccharide

31 March 2020

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Genetic and functional characterization of an antiserum to the lipid A-specific triggering receptor on murine B lymphocytes

31 March 2020

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The Primary Role of Lymphoreticnlar Cells in the Mediation of Host Responses to Bacterial Endotoxim

31 March 2020

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OBSERVATIONS ON MODE OF ACTION OF ENDOTOXIN IN CHICK EMBRYOS

31 March 2020

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Comparative studies on the toxicity of Escherichia coli lipopolysaccharide endotoxin in various animal species

31 March 2020

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Endotoxins and the immune response.

31 March 2020

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The immune response against Francisella tularensis live vaccine strain in Lps(n) and Lps(d) mice

31 March 2020

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Otitis media incidence and impact on the auditory brain stem response in lipopolysaccharide-nonresponsive C3H/HeJ mice.

31 March 2020

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Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

31 March 2020

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Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin

31 March 2020

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The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection

31 March 2020

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Protective effects of tumor necrosis factor in experimental Legionella pneumophila infections of mice via activation of PMN function

31 March 2020

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Pretreatment with recombinant murine tumor necrosis factor alpha/cachectin and murine interleukin 1 alpha protects mice from lethal bacterial infection

31 March 2020

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Genetic Control of Leucocyte Responses to Endotoxin

31 March 2020

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Interleukin 1-induced pathophysiology: induction of cytokines, development of histopathologic changes, and immunopharmacologic intervention

31 March 2020

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Interferon gamma receptor deficient mice are resistant to endotoxic shock

31 March 2020

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Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum

31 March 2020

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Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages

31 March 2020

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Structure and function of lipopolysaccharide binding protein

31 March 2020

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CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

31 March 2020

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Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages

31 March 2020

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

31 March 2020

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Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages

31 March 2020

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Phosphatidylinositol 3-kinase-dependent activation of protein kinase C-zeta in bacterial lipopolysaccharide-treated human monocytes

31 March 2020

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Genetic and Physical Mapping of theLpsLocus: Identification of the Toll-4 Receptor as a Candidate Gene in the Critical Region

31 March 2020

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

31 March 2020

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Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene product.

31 March 2020

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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

31 March 2020

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kappa B-like motifs regulate the induction of immune genes in Drosophila

31 March 2020

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Drosophila Toll and IL-1 receptor

31 March 2020

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Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1

31 March 2020

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Chromosomal localization of TIL, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14.

31 March 2020

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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

31 March 2020

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The serine protease inhibitor antithrombin III inhibits LPS-mediated NF-kappaB activation by TLR-4.

31 March 2020

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Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation

31 March 2020

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Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide

31 March 2020

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Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2

31 March 2020

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A family of human receptors structurally related to Drosophila Toll

31 March 2020

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TLR6: A novel member of an expanding toll-like receptor family

31 March 2020

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Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells

31 March 2020

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Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

31 March 2020

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Discrimination of bacterial lipoproteins by Toll-like receptor 6

31 March 2020

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A Toll-like receptor recognizes bacterial DNA

31 March 2020

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Unresponsiveness of MyD88-deficient mice to endotoxin

31 March 2020

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Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

31 March 2020

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

31 March 2020

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The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

31 March 2020

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Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

31 March 2020

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The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

31 March 2020

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

31 March 2020

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Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments

31 March 2020

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MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

31 March 2020

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Essential role of MD-2 in LPS responsiveness and TLR4 distribution.

31 March 2020

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Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling

31 March 2020

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The effect of endotoxin on resistance to infection and disease

31 March 2020

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inferred from DOI database lookup

7 January 2021

based on heuristic

Mouse genetic locus Lps influences susceptibility to Neisseria meningitidis infection

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inferred from DOI database lookup

7 January 2021

based on heuristic

Insect immunity: developmental and inducible activity of the Drosophila diptericin promoter

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1038/NRI1004

Identifiers

DOI

10.1038/NRI1004

1 reference

6 August 2017

1 reference

PubMed ID

12563300