Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q35058697)
Watch
English
Imatinib alone and in combination for chronic myeloid leukemia
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12563611
retrieved
6 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Imatinib alone and in combination for chronic myeloid leukemia
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12563611
retrieved
6 August 2017
main subject
chronic myeloid leukemia
0 references
leukemia
1 reference
based on heuristic
inferred from title
imatinib
1 reference
based on heuristic
inferred from title
author
Brian Druker
object named as
Brian J Druker
series ordinal
1
0 references
publication date
1 January 2003
1 reference
stated in
Europe PubMed Central
PubMed ID
12563611
retrieved
6 August 2017
published in
Seminars in Hematology
1 reference
stated in
Europe PubMed Central
PubMed ID
12563611
retrieved
6 August 2017
volume
40
1 reference
stated in
Europe PubMed Central
PubMed ID
12563611
retrieved
6 August 2017
page(s)
50-58
1 reference
stated in
Europe PubMed Central
PubMed ID
12563611
retrieved
6 August 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12563611
retrieved
6 August 2017
cites work
High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic myelogenous leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the ABL kinase activity blocks the proliferation of BCR/ABL+ leukemic cells and induces apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ph(+) acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Imatinib mesylate (STI571) inhibits growth of primitive malignant progenitors in chronic myelogenous leukemia through reversal of abnormally increased proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overcoming STI571 resistance with the farnesyl transferase inhibitor SCH66336.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol-3 kinase inhibitors enhance the anti-leukemia effect of STI571.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro studies of the combination of imatinib mesylate (Gleevec) and arsenic trioxide (Trisenox) in chronic myelogenous leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insights from pre-clinical studies for new combination treatment regimens with the Bcr-Abl kinase inhibitor imatinib mesylate (Gleevec/Glivec) in chronic myelogenous leukemia: a translational perspective.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of combinations of therapeutic agents on the proliferation of progenitor cells in chronic myeloid leukaemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of the Bcr/abl kinase inhibitors STI571 and adaphostin (NSC 680410) on chronic myelogenous leukemia cells in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The impact of clonal evolution on response to imatinib mesylate (STI571) in accelerated phase CML.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ARG tyrosine kinase activity is inhibited by STI571.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Co-treatment with As2O3 enhances selective cytotoxic effects of STI-571 against Brc-Abl-positive acute leukemia cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of effects of the tyrosine kinase inhibitors AG957, AG490, and STI571 on BCR-ABL--expressing cells, demonstrating synergy between AG490 and STI571.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergistic activity of the new ABL-specific tyrosine kinase inhibitor STI571 and chemotherapeutic drugs on BCR-ABL-positive chronic myelogenous leukemia cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: a prospective study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0037-1963%2803%2970042-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0037-1963(03)70042-0
1 reference
stated in
Europe PubMed Central
PubMed ID
12563611
retrieved
6 August 2017
PubMed ID
12563611
1 reference
stated in
Europe PubMed Central
PubMed ID
12563611
retrieved
6 August 2017
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit