(Q35074889)

6 August 2017

title

Proteomics: the first decade and beyond (English)

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6 August 2017

Scott D Patterson

1

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6 August 2017

Ruedi H Aebersold

series ordinal

2

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6 August 2017

publication date

1 March 2003

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6 August 2017

language of work or name

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6 August 2017

volume

33 Suppl

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6 August 2017

page(s)

311-323

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publication type of scholarly work

6 August 2017

review article

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Equipping scientists for the new biology

cites work

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7 January 2021

Structural genomics takes off.

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7 January 2021

Quantitative monitoring of gene expression patterns with a complementary DNA microarray

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7 January 2021

Serial analysis of gene expression

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7 January 2021

Internal amino acid sequence analysis of proteins separated by one- or two-dimensional gel electrophoresis after in situ protease digestion on nitrocellulose

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7 January 2021

Protein-blotting on Polybrene-coated glass-fiber sheets. A basis for acid hydrolysis and gas-phase sequencing of picomole quantities of protein previously separated on sodium dodecyl sulfate/polyacrylamide gel.

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7 January 2021

Internal sequence analysis of proteins separated on polyacrylamide gels at the submicrogram level: improved methods, applications and gene cloning strategies

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7 January 2021

Complementary DNA sequencing: expressed sequence tags and human genome project

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7 January 2021

3,400 new expressed sequence tags identify diversity of transcripts in human brain

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7 January 2021

Gene expression profiles in normal and cancer cells

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7 January 2021

Normalization and subtraction: two approaches to facilitate gene discovery

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7 January 2021

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7 January 2021

The Sequence of the Human Genome

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7 January 2021

Initial sequencing and analysis of the human genome

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7 January 2021

Electrospray ionization for mass spectrometry of large biomolecules

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7 January 2021

Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons

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7 January 2021

Protein and polymer analyses up tom/z 100 000 by laser ionization time-of-flight mass spectrometry

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7 January 2021

Identifying proteins from two-dimensional gels by molecular mass searching of peptide fragments in protein sequence databases

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7 January 2021

Use of mass spectrometric molecular weight information to identify proteins in sequence databases

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7 January 2021

Rapid identification of proteins by peptide-mass fingerprinting

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7 January 2021

Protein identification by mass profile fingerprinting.

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7 January 2021

Peptide mass maps: a highly informative approach to protein identification

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7 January 2021

Mass spectrometric approaches for the identification of gel-separated proteins

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7 January 2021

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

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7 January 2021

Electrospray and Taylor-Cone theory, Dole's beam of macromolecules at last?

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7 January 2021

Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry

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7 January 2021

Proteomics: applications in basic and applied biology

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7 January 2021

Progress with proteome projects: why all proteins expressed by a genome should be identified and how to do it.

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7 January 2021

Correlation between protein and mRNA abundance in yeast

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7 January 2021

Prognostic value of plasma interleukin-6 levels in patients with chronic lymphocytic leukemia

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7 January 2021

Reference distributions for the negative acute-phase proteins, albumin, transferrin, and transthyretin: a comparison of a large cohort to the world's literature

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7 January 2021

Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology

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7 January 2021

Analysis of the mouse proteome. (I) Brain proteins: separation by two-dimensional electrophoresis and identification by mass spectrometry and genetic variation

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7 January 2021

Two-dimensional gel electrophoresis in proteomics: Old, old fashioned, but it still climbs up the mountains

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7 January 2021

Advances in protein solubilisation for two-dimensional electrophoresis

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7 January 2021

Difference gel electrophoresis. A single gel method for detecting changes in protein extracts

1 reference

7 January 2021

A comparison between Sypro Ruby and ruthenium II tris (bathophenanthroline disulfonate) as fluorescent stains for protein detection in gels

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7 January 2021

Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry

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7 January 2021

HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation

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7 January 2021

Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad

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7 January 2021

Direct Analysis of Protein Mixtures by Tandem Mass Spectrometry

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7 January 2021

IPPC '99. Proceedings of the 1st Pacific Rim 2-DE Meeting. Tokyo, Japan, August 29-September 1, 1999

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7 January 2021

An automated multidimensional protein identification technology for shotgun proteomics

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7 January 2021

Direct analysis of protein complexes using mass spectrometry

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7 January 2021

Purification and biochemical characterization of interchromatin granule clusters

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7 January 2021

Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition

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7 January 2021

Towards defining the urinary proteome using liquid chromatography-tandem mass spectrometry. I. Profiling an unfractionated tryptic digest

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7 January 2021

Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry

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7 January 2021

Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes

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7 January 2021

Quantitative profiling of differentiation-induced microsomal proteins using isotope-coded affinity tags and mass spectrometry

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7 January 2021

The yeast nuclear pore complex: composition, architecture, and transport mechanism

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7 January 2021

Large-scale analysis of the yeast proteome by multidimensional protein identification technology

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7 January 2021

Electrospray ionization mass spectrometry of phosphopeptides isolated by on-line immobilized metal-ion affinity chromatography

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7 January 2021

Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae

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7 January 2021

Specific isolation of O-linked N-acetylglucosamine glycopeptides from complex mixtures

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7 January 2021

Selective Detection and Site-Analysis of O-GlcNAc-Modified Glycopeptides by β-Elimination and Tandem Electrospray Mass Spectrometry

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7 January 2021

Automated LC-LC-MS-MS platform using binary ion-exchange and gradient reversed-phase chromatography for improved proteomic analyses

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7 January 2021

Proteome analysis of low-abundance proteins using multidimensional chromatography and isotope-coded affinity tags

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7 January 2021

An accurate mass tag strategy for quantitative and high-throughput proteome measurements

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7 January 2021

Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

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7 January 2021

Quantitation and facilitated de novo sequencing of proteins by isotopic N-terminal labeling of peptides with a fragmentation-directing moiety

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7 January 2021

De novo peptide sequencing and quantitative profiling of complex protein mixtures using mass-coded abundance tagging

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7 January 2021

Quantitative proteome analysis by solid-phase isotope tagging and mass spectrometry

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7 January 2021

Quantitation of peptides and proteins by matrix-assisted laser desorption/ionization mass spectrometry using (18)O-labeled internal standards

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7 January 2021

Proteolytic 18O labeling for comparative proteomics: model studies with two serotypes of adenovirus

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7 January 2021

Accurate quantitation of protein expression and site-specific phosphorylation

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7 January 2021

Quantitative analysis of bacterial and mammalian proteomes using a combination of cysteine affinity tags and 15N-metabolic labeling

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7 January 2021

Rapid quantitative measurements of proteomes by Fourier transform ion cyclotron resonance mass spectrometry

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7 January 2021

Analysis of quantitative proteomic data generated via multidimensional protein identification technology

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7 January 2021

Molecular features of B-cell lymphoma

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7 January 2021

Identification of genes over-expressed in small cell lung carcinoma using suppression subtractive hybridization and cDNA microarray expression analysis

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7 January 2021

Gene expression profiling predicts clinical outcome of breast cancer

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7 January 2021

Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization

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7 January 2021

Functional discovery via a compendium of expression profiles

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7 January 2021

Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles

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7 January 2021

Cluster analysis and display of genome-wide expression patterns

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7 January 2021

Singular value decomposition for genome-wide expression data processing and modeling

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7 January 2021

Integrated genomic and proteomic analyses of a systematically perturbed metabolic network

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7 January 2021

A comparison of selected mRNA and protein abundances in human liver

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7 January 2021

A sampling of the yeast proteome

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7 January 2021

Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling

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7 January 2021

Complementary profiling of gene expression at the transcriptome and proteome levels in Saccharomyces cerevisiae

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7 January 2021

Profiling the specific reactivity of the proteome with non-directed activity-based probes

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7 January 2021

Proteomic profiling of mechanistically distinct enzyme classes using a common chemotype

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7 January 2021

Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools

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7 January 2021

Protease degradomics: a new challenge for proteomics

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7 January 2021

Substrate binding and sequence preference of the proteasome revealed by active-site-directed affinity probes

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7 January 2021

Chemical strategies for the global analysis of protein function

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7 January 2021

Chemical approaches for functionally probing the proteome

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7 January 2021

Profiling serine hydrolase activities in complex proteomes

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7 January 2021

Activity-based protein profiling: the serine hydrolases

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7 January 2021

Approaches to labeling and identification of active site residues in glycosidases

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7 January 2021

Gamma-phosphate-linked ATP-sepharose for the affinity purification of protein kinases. Rapid purification to homogeneity of skeletal muscle mitogen-activated protein kinase kinase

1 reference

7 January 2021

Mass spectrometry in coupling with affinity capture-release and isotope-coded affinity tags for quantitative protein analysis

1 reference

7 January 2021

Affinity chromatography on immobilized anhydrotrypsin: general utility for selective isolation of C-terminal peptides from protease digests of proteins

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7 January 2021

Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing

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7 January 2021

Identification of incompletely processed potential Carboxypeptidase E substrates from CpEfat/CpEfat mice

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7 January 2021

Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

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7 January 2021

Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1

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7 January 2021

Immobilized metal ion affinity chromatography. Effect of solute structure, ligand density and salt concentration on the retention of peptides

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7 January 2021

Immobilized gallium(III) affinity chromatography of phosphopeptides

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7 January 2021

Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome

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7 January 2021

Phosphoprotein isotope-coded affinity tag approach for isolating and quantitating phosphopeptides in proteome-wide analyses

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7 January 2021

A systematic approach to the analysis of protein phosphorylation

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7 January 2021

Proteomics to study genes and genomes

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7 January 2021

Charting the protein complexome in yeast by mass spectrometry.

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7 January 2021

From molecular to modular cell biology

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7 January 2021

Functional organization of the yeast proteome by systematic analysis of protein complexes

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7 January 2021

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

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7 January 2021

Comparative assessment of large-scale data sets of protein-protein interactions

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7 January 2021

The study of macromolecular complexes by quantitative proteomics

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7 January 2021

Light-generated oligonucleotide arrays for rapid DNA sequence analysis

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7 January 2021

Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer

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7 January 2021

DNA microarrays: raising the profile

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7 January 2021

Statistical issues with microarrays: processing and analysis

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7 January 2021

Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions

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7 January 2021

Arrays for protein expression profiling: Towards a viable alternative to two-dimensional gel electrophoresis?

1 reference

7 January 2021

Solution and chip arrays in protein profiling

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7 January 2021

Phage antibodies: filamentous phage displaying antibody variable domains

1 reference

7 January 2021

The making of the minibody: an engineered beta-protein for the display of conformationally constrained peptides

1 reference

7 January 2021

Coupling protein design and in vitro selection strategies: improving specificity and affinity of a designed beta-protein IL-6 antagonist

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7 January 2021

Tendamistat as a scaffold for conformationally constrained phage peptide libraries

1 reference

7 January 2021

A combinatorial library of an alpha-helical bacterial receptor domain

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7 January 2021

Designing DNA-binding proteins on the surface of filamentous phage

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7 January 2021

The use of aptamers in large arrays for molecular diagnostics

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7 January 2021

The use of recombinant antibodies in proteomics

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7 January 2021

Anti-idiotypic protein domains selected from protein A-based affibody libraries

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7 January 2021

A perspective on protein microarrays

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7 January 2021

Protein and antibody arrays and their medical applications

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7 January 2021

Protein arrays for gene expression and molecular interaction screening

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7 January 2021

Multiplexed protein profiling on microarrays by rolling-circle amplification

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7 January 2021

Towards quantitative assays with peptide chips: a surface engineering approach

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7 January 2021

A biochemical genomics approach for identifying genes by the activity of their products.

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7 January 2021

Peptide chips for the quantitative evaluation of protein kinase activity

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7 January 2021

Analysis of yeast protein kinases using protein chips.

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7 January 2021

Genome-wide location and function of DNA binding proteins

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7 January 2021

Massive parallel analysis of the binding specificity of histone-like protein HU to single- and double-stranded DNA with generic oligodeoxyribonucleotide microchips

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7 January 2021

Large-scale identification of secreted and membrane-associated gene products using DNA microarrays

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7 January 2021

Messenger RNA translation state: the second dimension of high-throughput expression screening

1 reference

7 January 2021

Protein nanoarrays generated by dip-pen nanolithography

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7 January 2021

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

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7 January 2021

A novel genetic system to detect protein-protein interactions

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7 January 2021

Towards an understanding of complex protein networks

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7 January 2021

A protein linkage map of Escherichia coli bacteriophage T7.

1 reference

7 January 2021

Genome-wide analysis of vaccinia virus protein-protein interactions

1 reference

7 January 2021

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

1 reference

7 January 2021

Toward a protein-protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all possible combinations between the yeast proteins

1 reference

7 January 2021

A comprehensive two-hybrid analysis to explore the yeast protein interactome

1 reference

7 January 2021

The protein-protein interaction map of Helicobacter pylori

1 reference

7 January 2021

Protein interaction mapping in C. elegans using proteins involved in vulval development

1 reference

7 January 2021

A protein-protein interaction map of the Caenorhabditis elegans 26S proteasome

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7 January 2021

Yeast three-hybrid system to detect and analyze RNA-protein interactions

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7 January 2021

A yeast sensor of ligand binding.

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7 January 2021

Wavelength mutations and posttranslational autoxidation of green fluorescent protein

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7 January 2021

The green fluorescent protein

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7 January 2021

Seeing the Machinery of Live Cells

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7 January 2021

Subcellular localization of the yeast proteome

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7 January 2021

YPD-A database for the proteins of Saccharomyces cerevisiae

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7 January 2021

SGD: Saccharomyces Genome Database

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7 January 2021

Quantitative proteomic analysis of Myc oncoprotein function

1 reference

7 January 2021

Base-Calling of Automated Sequencer Traces UsingPhred. I. Accuracy Assessment

1 reference

7 January 2021

Base-Calling of Automated Sequencer Traces Using Phred. II. Error Probabilities

1 reference

7 January 2021

Experimental Protein Mixture for Validating Tandem Mass Spectral Analysis

1 reference

7 January 2021

Molecular Imaging of Biological Samples: Localization of Peptides and Proteins Using MALDI-TOF MS

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7 January 2021

Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues

1 reference

7 January 2021

Resonance shifts in the excitation of the n = 0, K = 1 to 6 quadrupolar resonances for ions confined in a linear ion trap

1 reference

7 January 2021

The characteristics of peptide collision-induced dissociation using a high-performance MALDI-TOF/TOF tandem mass spectrometer

1 reference

7 January 2021

Fourier transform ion cyclotron resonance mass spectrometry: A primer

1 reference

7 January 2021

Cartography of neurexins: more than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons

1 reference

7 January 2021

Use of proteomic patterns in serum to identify ovarian cancer

1 reference

7 January 2021

Robustness in bacterial chemotaxis

1 reference

7 January 2021

Combinatorial synthesis of genetic networks

1 reference

7 January 2021

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