(Q35075758)

6 August 2017

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title

How the ubiquitin-proteasome system controls transcription (English)

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ubiquitin-proteasome system

6 August 2017

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2

William P Tansey

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6 August 2017

Masafumi Muratani

1

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6 August 2017

1 March 2003

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Nature Reviews Molecular Cell Biology

6 August 2017

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6 August 2017

4

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6 August 2017

192-201

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6 August 2017

3

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https://scigraph.springernature.com/pub.10.1038/nrm1049

6 August 2017

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A function for monoubiquitination in the internalization of a G protein-coupled receptor.

31 March 2020

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Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain

31 March 2020

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The 19S Regulatory Complex of the Proteasome Functions Independently of Proteolysis in Nucleotide Excision Repair

31 March 2020

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Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24

31 March 2020

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Amino-terminal sequence identity of ubiquitin and the nonhistone component of nuclear protein A24

31 March 2020

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Selective arrangement of ubiquitinated and D1 protein-containing nucleosomes within the drosophila genome

31 March 2020

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Ubiquitinated histone H2B is preferentially located in transcriptionally active chromatin

31 March 2020

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Level of ubiquitinated histone H2B in chromatin is coupled to ongoing transcription

31 March 2020

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The active immunoglobulin kappa chain gene is packaged by non-ubiquitin-conjugated nucleosomes

31 March 2020

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Ubiquitin-activating/conjugating activity of TAFII250, a mediator of activation of gene expression in Drosophila

31 March 2020

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Ubiquitination of histone H3 in elongating spermatids of rat testes.

31 March 2020

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Rad6-dependent ubiquitination of histone H2B in yeast

31 March 2020

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The E2 ubiquitin conjugase Rad6 is required for the ArgR/Mcm1 repression of ARG1 transcription

31 March 2020

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The ubiquitin-conjugating enzyme Rad6 (Ubc2) is required for silencing in Saccharomyces cerevisiae

31 March 2020

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Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast

31 March 2020

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Components of the SAGA histone acetyltransferase complex are required for repressed transcription of ARG1 in rich medium

31 March 2020

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Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast

31 March 2020

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Gene silencing: trans-histone regulatory pathway in chromatin

31 March 2020

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Histone methylation versus histone acetylation: new insights into epigenetic regulation

31 March 2020

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The language of covalent histone modifications

31 March 2020

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Rapid turnover of the histone-ubiquitin conjugate, protein A24

31 March 2020

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Recruitment of a 19S proteasome subcomplex to an activated promoter

31 March 2020

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Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes

31 March 2020

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Active genes are tri-methylated at K4 of histone H3

31 March 2020

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Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators

31 March 2020

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A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae

31 March 2020

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Molecular characterization of Saccharomyces cerevisiae TFIID.

31 March 2020

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Mechanisms of transcription-coupled DNA repair

31 March 2020

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Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro

31 March 2020

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Rsp5 ubiquitin-protein ligase mediates DNA damage-induced degradation of the large subunit of RNA polymerase II in Saccharomyces cerevisiae

31 March 2020

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The large subunit of RNA polymerase II is a substrate of the Rsp5 ubiquitin-protein ligase

31 March 2020

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Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

31 March 2020

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Ubiquitination of RNA polymerase II large subunit signaled by phosphorylation of carboxyl-terminal domain

31 March 2020

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Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors

31 March 2020

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A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage

31 March 2020

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STATs and gene regulation

31 March 2020

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

31 March 2020

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The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

31 March 2020

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Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing.

31 March 2020

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Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

31 March 2020

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Pondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nuclear bodies

31 March 2020

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Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

31 March 2020

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PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

31 March 2020

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SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization

31 March 2020

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Transcription factor Sp3 is silenced through SUMO modification by PIAS1

31 March 2020

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Covalent attachment of the SUMO-1 protein to the negative regulatory domain of the c-Myb transcription factor modifies its stability and transactivation capacity

31 March 2020

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PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription

31 March 2020

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Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity

31 March 2020

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Transcriptional activity of CCAAT/enhancer-binding proteins is controlled by a conserved inhibitory domain that is a target for sumoylation

31 March 2020

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Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors

31 March 2020

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Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4.

31 March 2020

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Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex

31 March 2020

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Dual regulation of the met4 transcription factor by ubiquitin-dependent degradation and inhibition of promoter recruitment

31 March 2020

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beta-catenin is a target for the ubiquitin-proteasome pathway

31 March 2020

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

31 March 2020

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Mdm2 promotes the rapid degradation of p53

31 March 2020

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

31 March 2020

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2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway: role of the transcription activaton and DNA binding of AhR

31 March 2020

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Ubiquitin-dependent degradation of TGF-beta-activated smad2.

31 March 2020

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Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway

31 March 2020

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An internal region of the RpoH heat shock transcription factor is critical for rapid degradation by the FtsH protease

31 March 2020

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Regulation of RpoS proteolysis in Escherichia coli: the response regulator RssB is a recognition factor that interacts with the turnover element in RpoS

31 March 2020

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Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc.

31 March 2020

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Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency in vivo

31 March 2020

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Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase

31 March 2020

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Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase

31 March 2020

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A kinase-cyclin pair in the RNA polymerase II holoenzyme.

31 March 2020

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Transcriptional activation: risky business

31 March 2020

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Transcriptional regulation: Kamikaze activators

31 March 2020

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Regulation of transcriptional activation domain function by ubiquitin

31 March 2020

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RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit

31 March 2020

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The 26S proteasome: a molecular machine designed for controlled proteolysis

31 March 2020

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Alterations in a yeast protein resembling HIV Tat-binding protein relieve requirement for an acidic activation domain in GAL4.

31 March 2020

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Isolation and characterization of SUG2. A novel ATPase family component of the yeast 26 S proteasome.

31 March 2020

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A highly conserved ATPase protein as a mediator between acidic activation domains and the TATA-binding protein.

31 March 2020

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Mammalian Sug1 and c-Fos in the nuclear 26S proteasome

31 March 2020

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GAL4 interacts with TATA-binding protein and coactivators

31 March 2020

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Multiple mammalian proteasomal ATPases, but not proteasome itself, are associated with TATA-binding protein and a novel transcriptional activator, TIP120

31 March 2020

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The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor

31 March 2020

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A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.

31 March 2020

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Evidence that proteolysis of Gal4 cannot explain the transcriptional effects of proteasome ATPase mutations

31 March 2020

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The 19S regulatory particle of the proteasome is required for efficient transcription elongation by RNA polymerase II.

31 March 2020

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Three functional classes of transcriptional activation domain

31 March 2020

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Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes

31 March 2020

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The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain

31 March 2020

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SUG1, a component of the 26 S proteasome, is an ATPase stimulated by specific RNAs

31 March 2020

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Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex

31 March 2020

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Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II

31 March 2020

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Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex

31 March 2020

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A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

31 March 2020

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TOM1p, a yeast hect-domain protein which mediates transcriptional regulation through the ADA/SAGA coactivator complexes.

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRM1049

1 reference

6 August 2017

1 reference

PubMed ID

12612638