(Q35086330)

6 August 2017

title

Mutagenic and cytotoxic activity of benzol[a]pyrene 4,5-, 7,8-, and 9,10-oxides and the six corresponding phenols (English)

1 reference

6 August 2017

0 references

7

P. M. Dansette

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1103140

22 August 2022

author name string

A. W. Wood

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1103140

22 August 2022

R. L. Goode

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1103140

22 August 2022

R. L. Chang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1103140

22 August 2022

W. Levin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1103140

22 August 2022

A. H. Conney

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1103140

22 August 2022

H. Yagi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1103140

22 August 2022

D. M. Jerina

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1103140

22 August 2022

language of work or name

English

0 references

publication date

1 August 1975

1 reference

full work available at URL

6 August 2017

https://europepmc.org/articles/PMC432944

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1103140

https://europepmc.org/articles/PMC432944?pdf=render

22 August 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1103140

Proceedings of the National Academy of Sciences of the United States of America

22 August 2022

published in

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6 August 2017

volume

72

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6 August 2017

issue

8

1 reference

6 August 2017

page(s)

3176-3180

1 reference

Mutagenicity to mammalian cells of epoxides and other derivatives of polycyclic hydrocarbons

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Mammalian cell genetics. II. Chemical induction of specific locus mutations in Chinese hamster cells in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Binding of K-region epoxides and other derivatives of benz(a)anthracene and dibenz(a,h)anthracene to DNA, RNA, and proteins of transformable cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Malignant transformation of cells derived from mouse prostate by epoxides and other derivatives of polycyclic hydrocarbons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Arene oxides: a new aspect of drug metabolism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Malignant transformationin vitro of mouse fibroblasts by 7, 12-dimethylbenz(A)anthracene and 7-hydroxymethylbenz(A)anthracene and by their K-region derivatives

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Facile synthesis of arene oxides at the K regions of polycyclic hydrocarbons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Metabolic conversion of benzo[a]pyrene by Syrian hamster liver microsomes and binding of metabolites to deoxyribonucleic acid

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Isolation and characterization of an active DNA-binding metabolite of benzo(a)pyrene from hamster liver microsomal incubation systems

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Epoxides in polycyclic aromatic hydrocarbon metabolism and carcinogenesis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Dependence of specific metabolism of benzo(a)pyrene on the inducer of hydroxylase activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Epoxides of Carcinogenic Polycyclic Hydrocarbons Are Frameshift Mutagens

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Effects of Inducers and Epoxide Hydrase on the Metabolism of Benzo[ a ]pyrene by Liver Microsomes and a Reconstituted System: Analysis by High Pressure Liquid Chromatography

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Transformation of hamster embryo cells by epoxides and other derivatives of polycyclic hydrocarbons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

In vitro transformation of rodent cells by K-region derivatives of polycyclic hydrocarbons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Comparison of the cellular DNA-bound products of benzo(alpha)pyrene with the products formed by the reaction of benzo(alpha)pyrene-4,5-oxide with DNA

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432944

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

8 July 2018

1 reference

12 December 2020

Early differential effects of 3-methylcholanthrene and its "K-region" epoxide on mouse skin. Possible implication in the two-stage mechanism of tumorigenesis

1 reference

12 December 2020

High-pressure liquid chromatographic analysis of benzo(alpha)pyrene metabolism and covalent binding and the mechanism of action of 7,8-benzoflavone and 1,2-epoxy-3,3,3-trichloropropane

1 reference

12 December 2020

Formation of K-region epoxides as microsomal metabolites of pyrene and benzo(a)pyrene

1 reference

12 December 2020

Interactions of the K-region epoxides of phenanthrene and dibenz (a,h)anthracene with nucleic acids and histone

1 reference

12 December 2020

Low Carcinogenicity of the K-Region Epoxides of 7-Methylbenz(a)-anthracene and Benz (a) anthracene in the Mouse and Rat

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.72.8.3176

1 reference

6 August 2017

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1 reference

6 August 2017

1 reference