(Q35091267)

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Gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosis

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 August 2017

retracted paper

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Dataset for "Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine"

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

Gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

phosphorylation

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Sahdeo Prasad

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Manoj K Pandey

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Vivek R Yadav

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Bharat B Aggarwal

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

publication date

13 April 2011

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Cancer Prevention Research

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1084-1094

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3131433/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway

1 reference

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Mechanisms of gambogic acid-induced apoptosis in non-small cell lung cancer cells in relation to transferrin receptors

1 reference

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1 reference

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Betulinic acid suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase SHP-1 in human multiple myeloma cells

1 reference

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An oxidative analogue of gambogic acid-induced apoptosis of human hepatocellular carcinoma cell line HepG2 is involved in its anticancer activity in vitro

1 reference

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The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma

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1 reference

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1 reference

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Proteomic identification of molecular targets of gambogic acid: role of stathmin in hepatocellular carcinoma.

1 reference

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1 reference

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Gambogic acid induced tumor cell apoptosis by T lymphocyte activation in H22 transplanted mice

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Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling.

1 reference

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Gambogic acid, a potent inhibitor of survivin, reverses docetaxel resistance in gastric cancer cells

1 reference

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Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer

1 reference

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Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway

1 reference

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Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK+ anaplastic large-cell lymphoma

1 reference

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8 July 2018

Repression of telomerase reverse transcriptase mRNA and hTERT promoter by gambogic acid in human gastric carcinoma cells

1 reference

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8 July 2018

Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells

1 reference

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8 July 2018

A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid

1 reference

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8 July 2018

Stat3 is required for full neoplastic transformation by the Simian Virus 40 large tumor antigen

1 reference

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8 July 2018

Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131433

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Stat3 is required for the development of skin cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131433

8 July 2018

Gambogic acid induces apoptosis and regulates expressions of Bax and Bcl-2 protein in human gastric carcinoma MGC-803 cells

1 reference

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SOCS1 and SHP1 hypermethylation in multiple myeloma: implications for epigenetic activation of the Jak/STAT pathway

1 reference

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Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma Cells

1 reference

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The function of the protein tyrosine phosphatase SHP-1 in cancer

1 reference

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8 July 2018

The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation

1 reference

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Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB

1 reference

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8 July 2018

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131433

8 July 2018

Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention

1 reference

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NF-kappaB at the crossroads of life and death

1 reference

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8 July 2018

Involvement of tyrosine phosphatase PTP1D in the inhibition of interleukin-6-induced Stat3 signaling by alpha-thrombin

1 reference

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1 reference

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Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

1 reference

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STATs in oncogenesis

1 reference

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Stat3 as an oncogene

1 reference

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8 July 2018

Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells

1 reference

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8 July 2018

Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells.

1 reference

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8 July 2018

bFGF and LIF signaling activates STAT3 in proliferating myoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131433

8 July 2018

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

1 reference

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Constitutively Activated Jak-STAT Pathway in T Cells Transformed with HTLV-I

1 reference

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Cytokine receptor signalling

1 reference

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Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

1 reference

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8 July 2018

Gambogic acid inhibits angiogenesis through suppressing vascular endothelial growth factor-induced tyrosine phosphorylation of KDR/Flk-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131433

27 September 2018

Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131433

27 September 2018

Activation of stat3 in primary tumors from high-risk breast cancer patients is associated with elevated levels of activated SRC and survivin expression

1 reference

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Roles of activated Src and Stat3 signaling in melanoma tumor cell growth

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PTEN is a negative regulator of STAT3 activation in human papillomavirus-infected cells

1 reference

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Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotion of liver carcinogenesis by polychlorinated biphenyls.

1 reference

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EGFR dependent expression of STAT3 (but not STAT1) in breast cancer

1 reference

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Bcl-xl expression in multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21490133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1940-6207.CAPR-10-0340

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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