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The CD95(APO-1/Fas) DISC and beyond
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12655293
retrieved
6 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
The CD95(APO-1/Fas) DISC and beyond
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12655293
retrieved
6 August 2017
main subject
TRAIL death-inducing signaling complex
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0031266
CD95 death-inducing signaling complex
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0031265
death-inducing signaling complex
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0031264
author name string
Peter ME
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12655293
retrieved
6 August 2017
Krammer PH
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12655293
retrieved
6 August 2017
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
1 January 2003
1 reference
stated in
Europe PubMed Central
PubMed ID
12655293
retrieved
6 August 2017
published in
Cell Death & Differentiation
1 reference
stated in
Europe PubMed Central
PubMed ID
12655293
retrieved
6 August 2017
volume
10
1 reference
stated in
Europe PubMed Central
PubMed ID
12655293
retrieved
6 August 2017
page(s)
26-35
1 reference
stated in
Europe PubMed Central
PubMed ID
12655293
retrieved
6 August 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12655293
retrieved
6 August 2017
exact match
https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401186
0 references
cites work
Apoptosis signaling by death receptors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of a ligand-independent oligomerization domain in the extracellular region of the CD95 death receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
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7 January 2021
based on heuristic
inferred from DOI database lookup
A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
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7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian caspases: structure, activation, substrates, and functions during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the cytolinker plectin as a major early in vivo substrate for caspase 8 during CD95- and tumor necrosis factor receptor-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase activation: the induced-proximity model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-10 is an initiator caspase in death receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of death receptor signals by cellular FLIP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Casper is a FADD- and caspase-related inducer of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
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7 January 2021
based on heuristic
inferred from DOI database lookup
CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CASH, a novel caspase homologue with death effector domains
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
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7 January 2021
based on heuristic
inferred from DOI database lookup
MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
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7 January 2021
based on heuristic
inferred from DOI database lookup
I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of c-FLIP in modulation of CD95-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of NF-kappaB by FADD, Casper, and caspase-8.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor receptor and Fas signaling mechanisms.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Daxx, a novel Fas-binding protein that activates JNK and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequestration and inhibition of Daxx-mediated transcriptional repression by PML
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PML is essential for multiple apoptotic pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Daxx enigma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FAP-1: a protein tyrosine phosphatase that associates with Fas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of Fas-mediated apoptosis by FAP-1 in human cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Down-regulation of Fas-associated phosphatase-1 (FAP-1) in interleukin-2-activated T cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular interaction of Fas and FAP-1. A tripeptide blocker of human Fas interaction with FAP-1 promotes Fas-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis. Searching for FLASH domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure-function analysis of an evolutionary conserved protein, DAP3, which mediates TNF-alpha- and Fas-induced cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of DAP3 and FADD only after cellular disruption
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28 S small subunit
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoproteolytic activation of pro-caspases by oligomerization.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An induced proximity model for caspase-8 activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dimer formation drives the activation of the cell death protease caspase 9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of human caspases by peptide-based and macromolecular inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TCR-mediated up-regulation of c-FLIPshort correlates with resistance toward CD95-mediated apoptosis by blocking death-inducing signaling complex activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Up-regulation of c-FLIPshort and reduction of activation-induced cell death in CD28-costimulated human T cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two CD95 (APO-1/Fas) signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl–2 protects from lethal hepatic apoptosis induced by an ant–Fas antibody in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Target protease specificity of the viral serpin CrmA. Analysis of five caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Forced degradation of Fas inhibits apoptosis in adenovirus-infected cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The adenovirus E3/10.4K-14.5K proteins down-modulate the apoptosis receptor Fas/Apo-1 by inducing its internalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling through protein kinase C
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of apoptosis in T cells expressing human T cell leukemia virus type I Tax.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis through CD95 (Fas/APO-1), but not a CD40/CD95 chimeric receptor, is inhibited by phorbol-12-myristate-13-acetate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the protein kinase C pathway promotes anti-CD95-induced apoptosis in Jurkat T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective inhibition of protein kinase C isozymes by Fas ligation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
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7 January 2021
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inferred from DOI database lookup
p90(RSK) blocks bad-mediated cell death via a protein kinase C-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
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7 January 2021
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Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
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7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
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7 January 2021
based on heuristic
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A physical interaction between the cell death protein Fas and the tyrosine kinase p59fynT.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
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APO-1(CD95)-mediated apoptosis in Jurkat cells does not involve src kinases or CD45
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
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Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
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Bruton's tyrosine kinase as an inhibitor of the Fas/CD95 death-inducing signaling complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Death receptors bind SHP-1 and block cytokine-induced anti-apoptotic signaling in neutrophils
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
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Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
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7 January 2021
based on heuristic
inferred from DOI database lookup
FLICE-inhibitory protein is a key regulator of germinal center B cell apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ceramide enables fas to cap and kill.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD95 Signaling via Ceramide-rich Membrane Rafts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
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Molecular ordering of the initial signaling events of CD95.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potentiation of Fas-mediated apoptosis by an engineered glycosylphosphatidylinositol-linked Fas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas transduces activation signals in normal human T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
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A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase activation is required for T cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
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Caspase-dependent activation of cyclin-dependent kinases during Fas-induced apoptosis in Jurkat cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
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T cell receptor-induced activation and apoptosis in cycling human T cells occur throughout the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of human fas (CD95) with a ubiquitin-conjugating enzyme (UBC-FAP)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of Fas(Apo-1/CD95) with proteins implicated in the ubiquitination pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401186
retrieved
7 January 2021
based on heuristic
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Identifiers
DOI
10.1038/SJ.CDD.4401186
1 reference
stated in
Europe PubMed Central
PubMed ID
12655293
retrieved
6 August 2017
Dimensions Publication ID
1028177359
0 references
PubMed ID
12655293
1 reference
stated in
Europe PubMed Central
PubMed ID
12655293
retrieved
6 August 2017
ResearchGate publication ID
10840380
0 references
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