(Q35125971)

6 August 2017

1 reference

title

Role of telomeres and telomerase in the pathogenesis of human cancer (English)

1 reference

6 August 2017

Role of Telomeres and Telomerase in the Pathogenesis of Human Cancer (English)

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

1 January 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12743159

1 January 2024

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

1 January 2024

1

William C Hahn

1 reference

6 August 2017

language of work or name

English

0 references

publication date

1 May 2003

1 reference

6 August 2017

15 May 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12743159

full work available at URL

1 January 2024

https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2003.06.018

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Journal of Clinical Oncology

1 January 2024

published in

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6 August 2017

21

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6 August 2017

2034-2043

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6 August 2017

10

1 reference

Extension of life-span by introduction of telomerase into normal human cells

6 August 2017

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCIENCE.279.5349.349

The serial cultivation of human diploid cell strains

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/0014-4827(61)90192-6

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1101/GAD.828901

Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1128/MCB.20.4.1436-1447.2000

A telomerase component is defective in the human disease dyskeratosis congenita

1 reference

COCI

https://opencitations.net/index/coci/api/v1/citations/10.1038/990141

15 July 2023

The Hallmarks of Cancer

1

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomeres and their control

1 January 2024

2

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Conservation of the human telomere sequence (TTAGGG)n among vertebrates

1 January 2024

3

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes

1 January 2024

4

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

An overhanging 3' terminus is a conserved feature of telomeres

1 January 2024

5

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

1 January 2024

6

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

The terminal DNA structure of mammalian chromosomes

1 January 2024

7

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Normal human chromosomes have long G-rich telomeric overhangs at one end

1 January 2024

8

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Mammalian telomeres end in a large duplex loop

1 January 2024

9

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Protection of mammalian telomeres

1 January 2024

10

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

A human telomeric protein

1 January 2024

11

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

1 January 2024

12

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomeric localization of TRF2, a novel human telobox protein

1 January 2024

13

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Control of telomere length by the human telomeric protein TRF1

1 January 2024

14

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

TRF2 Protects Human Telomeres from End-to-End Fusions

1 January 2024

15

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

1 January 2024

16

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang

1 January 2024

17

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Pot1, the putative telomere end-binding protein in fission yeast and humans

1 January 2024

18

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase)

1 January 2024

19

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

1 January 2024

20

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

TIN2, a new regulator of telomere length in human cells

1 January 2024

21

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Identification of human Rap1: implications for telomere evolution

1 January 2024

22

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

1 January 2024

23

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Ku acts in a unique way at the mammalian telomere to prevent end joining

1 January 2024

24

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Ku is associated with the telomere in mammals

1 January 2024

25

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Ku binds telomeric DNA in vitro

1 January 2024

26

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

1 January 2024

27

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Reversing time: origin of telomerase

1 January 2024

28

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Role of telomerase in normal and cancer cells

1 January 2024

29

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

The RNA component of human telomerase

1 January 2024

30

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3' end

1 January 2024

31

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase catalytic subunit homologs from fission yeast and human

1 January 2024

32

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

1 January 2024

33

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Human telomerase contains evolutionarily conserved catalytic and structural subunits

1 January 2024

34

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Functional multimerization of the human telomerase reverse transcriptase

1 January 2024

35

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Two independent regions of human telomerase reverse transcriptase are important for its oligomerization and telomerase activity

1 January 2024

36

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Human telomerase contains two cooperating telomerase RNA molecules

1 January 2024

37

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Reverse transcriptase motifs in the catalytic subunit of telomerase

1 January 2024

38

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

The catalytic subunit of yeast telomerase

1 January 2024

39

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

1 January 2024

40

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

1 January 2024

41

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

1 January 2024

42

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo

1 January 2024

43

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

1 January 2024

44

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding

1 January 2024

45

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase

1 January 2024

46

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

A mammalian telomerase-associated protein

1 January 2024

47

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Functional requirement of p23 and Hsp90 in telomerase complexes

1 January 2024

48

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivo

1 January 2024

49

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Non-nucleosomal packaging of a tandemly repeated DNA sequence at termini of extrachromosomal DNA coding for rRNA in Tetrahymena

1 January 2024

51

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs.

1 January 2024

52

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 January 2024

53

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Inhibition of telomerase limits the growth of human cancer cells.

1 January 2024

54

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere states and cell fates.

1 January 2024

55

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Block in anaphase chromosome separation caused by a telomerase template mutation.

1 January 2024

56

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation

1 January 2024

57

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability

1 January 2024

58

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere fusions caused by mutating the terminal region of telomeric DNA

1 January 2024

59

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

1 January 2024

61

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase, cell immortality, and cancer

1 January 2024

62

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Specific association of human telomerase activity with immortal cells and cancer

1 January 2024

64

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere length predicts replicative capacity of human fibroblasts

1 January 2024

65

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomeres shorten during ageing of human fibroblasts

1 January 2024

66

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

1 January 2024

67

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase activity in human ovarian carcinoma

1 January 2024

68

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere reduction in human colorectal carcinoma and with ageing

1 January 2024

69

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Changes of telomere length in children after hematopoietic stem cell transplantation

1 January 2024

70

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Accelerated telomere shortening in young recipients of allogeneic bone-marrow transplants.

1 January 2024

71

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 January 2024

73

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Human endothelial cell life extension by telomerase expression

1 January 2024

74

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

1 January 2024

75

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

1 January 2024

76

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

A highly selective telomerase inhibitor limiting human cancer cell proliferation

1 January 2024

78

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Can ends justify the means?: telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells

1 January 2024

79

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Defining the molecular mechanisms of human cell immortalization

1 January 2024

80

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Cellular transformation by SV40 large T antigen: interaction with host proteins

1 January 2024

81

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Differentiation between senescence (M1) and crisis (M2) in human fibroblast cultures

1 January 2024

82

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen

1 January 2024

83

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase activity is sufficient to allow transformed cells to escape from crisis

1 January 2024

84

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 January 2024

86

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

1 January 2024

87

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Senescence Induced by Altered Telomere State, Not Telomere Loss

1 January 2024

89

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere elongation in immortal human cells without detectable telomerase activity

1 January 2024

90

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

A mutant with a defect in telomere elongation leads to senescence in yeast

1 January 2024

92

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae

1 January 2024

93

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere maintenance by recombination in human cells.

1 January 2024

94

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells

1 January 2024

95

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase can inhibit the recombination-based pathway of telomere maintenance in human cells

1 January 2024

96

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

A survey of telomerase activity in human cancer

1 January 2024

97

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase activity in normal and malignant hematopoietic cells

1 January 2024

99

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes

1 January 2024

101

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Clinical utility of telomerase in cancer

1 January 2024

105

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1 January 2024

106

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1 January 2024

107

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Resistance of human cells to tumorigenesis induced by cloned transforming genes

1 January 2024

108

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

From cells to organisms: can we learn about aging from cells in culture?

1 January 2024

109

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Senescence as a mode of tumor suppression

1 January 2024

110

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Creation of human tumour cells with defined genetic elements

1 January 2024

112

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Immortalization and transformation of primary human airway epithelial cells by gene transfer.

1 January 2024

113

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Critical role for SV40 small-t antigen in human cell transformation

1 January 2024

115

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Multiple stages of malignant transformation of human endothelial cells modelled by co-expression of telomerase reverse transcriptase, SV40 T antigen and oncogenic N-ras.

1 January 2024

116

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology

1 January 2024

117

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Developmental and tissue-specific regulation of mouse telomerase and telomere length

1 January 2024

119

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Hypervariable ultra-long telomeres in mice

1 January 2024

120

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Essential role of mouse telomerase in highly proliferative organs

1 January 2024

121

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

1 January 2024

122

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

1 January 2024

123

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

1 January 2024

Start making sense

124

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

1 January 2024

125

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase expression in intracranial tumours: prognostic potential for malignant gliomas and meningiomas

1 January 2024

126

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase activity in ordinary meningiomas predicts poor outcome

1 January 2024

127

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase activity and telomere length in thyroid neoplasia: biological and clinical implications

1 January 2024

128

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

The detection of telomerase activity in patients with adenocarcinoma of the pancreas by fine needle aspiration

1 January 2024

129

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase activity as a potential marker in preneoplastic bladder lesions.

1 January 2024

130

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase in relation to clinicopathologic prognostic factors and survival in cervical cancer

1 January 2024

131

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase activity in Papanicolaou smear-negative exfoliated cervical cells and its association with lesions and oncogenic human papillomaviruses

1 January 2024

132

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase activity in human breast tumors

1 January 2024

136

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Detection of telomerase activity in biopsy samples of colorectal cancer

1 January 2024

137

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Expression of TERT in early premalignant lesions and a subset of cells in normal tissues.

1 January 2024

138

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase contributes to tumorigenesis by a telomere length-independent mechanism

1 January 2024

139

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.

1 January 2024

140

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Constitutive telomerase expression promotes mammary carcinomas in aging mice

1 January 2024

141

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Dyskeratosis congenita in all its forms

1 January 2024

142

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

1 January 2024

144

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Cutting edge: telomerase activation in human T lymphocytes does not require increase in telomerase reverse transcriptase (hTERT) protein but is associated with hTERT phosphorylation and nuclear translocation

1 January 2024

145

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere length assessment in human archival tissues: combined telomere fluorescence in situ hybridization and immunostaining

1 January 2024

147

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Mechanism of human telomerase inhibition by BIBR1532, a synthetic, non-nucleosidic drug candidate.

1 January 2024

148

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

The beta subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA.

1 January 2024

149

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes

1 January 2024

150

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Characterization of a G-quartet formation reaction promoted by the beta-subunit of the Oxytricha telomere-binding protein

1 January 2024

152

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase as a potential molecular target to study G-quartet phosphorothioates

1 January 2024

153

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere maintenance as a target for anticancer drug discovery

1 January 2024

154

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Inhibition of telomerase by G-quartet DNA structures

1 January 2024

155

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Molecular targeting of cancer: telomeres as targets

1 January 2024

156

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase activation, cellular immortalization and cancer

1 January 2024

157

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters

1 January 2024

159

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Use of transcriptional regulatory sequences of telomerase (hTER and hTERT) for selective killing of cancer cells

1 January 2024

162

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells.

1 January 2024

163

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Identification of human telomerase reverse transcriptase-derived peptides that induce HLA-A24-restricted antileukemia cytotoxic T lymphocytes

1 January 2024

164

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes

1 January 2024

165

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomerase as a universal tumor-associated antigen for cancer immunotherapy

1 January 2024

167

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals

1 January 2024

168

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

1 January 2024

169

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

Telomere dysfunction alters the chemotherapeutic profile of transformed cells

1 January 2024

170

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.06.018

1 January 2024

Identifiers

1 reference

release_qxlmylv63bdthhnuuypjtwijmy

6 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qxlmylv63bdthhnuuypjtwijmy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference