(Q35128725)

6 August 2017

title

The prognostic impact of K-RAS mutations in adult acute myeloid leukemia patients treated with high-dose cytarabine (English)

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6 August 2017

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acute myeloid leukemia

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adult acute myeloid leukemia

inferred from title

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Ebtesam I Ahmad

1

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6 August 2017

Heba H Gawish

series ordinal

2

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6 August 2017

Nashwa Ma Al Azizi

series ordinal

3

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6 August 2017

Ashraf M Elhefni

series ordinal

4

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6 August 2017

language of work or name

English

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publication date

15 July 2011

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6 August 2017

published in

OncoTargets and Therapy

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6 August 2017

volume

4

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6 August 2017

page(s)

115-121

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Creative Commons Attribution-NonCommercial 3.0 Unported

6 August 2017

copyright license

start time

1 July 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Molecular genetic pathways as therapeutic targets in acute myeloid leukemia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Implications of NRAS mutations in AML: a study of 2502 patients

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Oncogenic RAS induces accelerated transition through G2/M and promotes defects in the G2 DNA damage and mitotic spindle checkpoints

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

RAS mutation in acute myeloid leukemia is associated with distinct cytogenetic subgroups but does not influence outcome in patients younger than 60 years

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

The normal response to RAS: senescence or transformation?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Ras gene mutations in patients with acute myeloid leukaemia and exposure to chemical agents

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.

13 July 2018

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Targeting RAS signalling pathways in cancer therapy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Mutations in ras proto-oncogenes are associated with lower mdr1 gene expression in adult acute myeloid leukaemia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Mutational activation of the K-ras oncogene and the effect of chemotherapy in advanced adenocarcinoma of the lung: a prospective study

13 July 2018

1 reference

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Ras triggers ataxia-telangiectasia-mutated and Rad-3-related activation and apoptosis through sustained mitogenic signaling.

13 July 2018

1 reference

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Activation of the RAS pathway is predictive for a chemosensitive phenotype of acute myelogenous leukemia blasts

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Activating mutations of RTK/ras signal transduction pathway in pediatric acute myeloid leukemia

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143910

Prognostic significance of N-RAS and K-RAS mutations in 232 patients with acute myeloid leukemia

27 September 2018

1 reference

12 December 2020

A rapid banding technique for human chromosomes

1 reference

12 December 2020

The incidence and prognostic significance of mutations in codon 13 of the N-ras gene in acute myeloid leukemia

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12 December 2020

Enhanced sensitivity to 1-beta-D-arabinofuranosylcytosine and topoisomerase II inhibitors in tumor cell lines harboring activated ras oncogenes

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12 December 2020

Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia

1 reference

12 December 2020

Ras oncogene-induced sensitization to 1-beta-D-arabinofuranosylcytosine

1 reference

12 December 2020

Second hit mutations in the RTK/RAS signaling pathway in acute myeloid leukemia with inv(16)

1 reference

12 December 2020

Identifiers

DOI

10.2147/OTT.S12602

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6 August 2017

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6 August 2017

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