(Q35129048)

6 August 2017

The conduct of in vitro and in vivo drug-drug interaction studies: a PhRMA perspective (English)

1 reference

6 August 2017

The Conduct of In Vitro and In Vivo Drug-Drug Interaction Studies: A PhRMA Perspective (English)

1 reference

10.1177/0091270003043005001

DOI

https://api.crossref.org/works/10.1177/0091270003043005001

3 January 2024

0 references

1 reference

10.1177/0091270003043005001

https://api.crossref.org/works/10.1177/0091270003043005001

3 January 2024

author name string

Volker Fischer

4

1 reference

6 August 2017

Lawrence Gan

5

1 reference

6 August 2017

Scott Grimm

6

1 reference

6 August 2017

John Kao

7

1 reference

6 August 2017

Gerald Miwa

9

1 reference

6 August 2017

Lan Ni

10

1 reference

6 August 2017

Gondi Kumar

11

1 reference

6 August 2017

James McLeod

12

1 reference

6 August 2017

Stanley Roberts

14

1 reference

6 August 2017

Amy Roe

15

1 reference

6 August 2017

Anita Shah

16

1 reference

6 August 2017

Fred Snikeris

17

1 reference

6 August 2017

Donald Tweedie

19

1 reference

6 August 2017

John Walsh

21

1 reference

6 August 2017

Pharmaceutical Research and Manufacturers of America Drug Metabolism/Clinical Pharmacology Technical Working Groups

23

1 reference

6 August 2017

Thorir D. Bjornsson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12751267

3 January 2024

John T. Callaghan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12751267

3 January 2024

Heidi J. Einolf

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12751267

3 January 2024

S. Peter King

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12751267

3 January 2024

Scott R. Obach

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12751267

3 January 2024

John T. Sullivan

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12751267

3 January 2024

Jose M. Vega

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12751267

3 January 2024

Steven A. Wrighton

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12751267

3 January 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12751267

3 January 2024

publication date

1 May 2003

1 reference

The Journal of Clinical Pharmacology

6 August 2017

1 reference

6 August 2017

43

1 reference

6 August 2017

443-469

1 reference

6 August 2017

5

1 reference

Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential--toward a consensus

6 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Drug metabolites in safety testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Drug-mediated inactivation of cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Heterotropic cooperativity of cytochrome P450 3A4 and potential drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

The use of heterologously expressed drug metabolizing enzymes--state of the art and prospects for the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Implications and consequences of enzyme induction on preclinical and clinical drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Induction of cytochrome P450 enzymes in cultured precision-cut human liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Detection of CYP1A1 protein in human liver and induction by TCDD in precision-cut liver slices incubated in dynamic organ culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Drug glucuronidation in clinical psychopharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Polymorphisms in UDP glucuronosyltransferase genes: functional consequences and clinical relevance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Induction of zidovudine glucuronidation and amination pathways by rifampicin in HIV-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Pharmacokinetic interaction between rifampin and zidovudine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

The pharmacokinetics of levosalbutamol: what are the clinical implications?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Role of transport proteins in drug absorption, distribution and excretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Evidence for a polarized efflux system in CACO-2 cells capable of modulating cyclosporin A transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Investigations on the metabolic pathways of cyclosporine: I. Excretion of cyclosporine and its metabolites in human bile—isolation of 12 new cyclosporine metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Effect of common excipients on Caco-2 transport of low-permeability drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Assessment of liver metabolic function. Clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Assessment of cytochrome P450 activity by a five-drug cocktail approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Chloroquine modulation of specific metabolizing enzymes activities: investigation with selective five drug cocktail

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Combined phenotypic assessment of CYP1A2, CYP2C19, CYP2D6, CYP3A, N-acetyltransferase-2, and xanthine oxidase with the "Cooperstown cocktail".

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Ritonavir increases loperamide plasma concentrations without evidence for P-glycoprotein involvement

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Effect of P-glycoprotein modulation on the clinical pharmacokinetics and adverse effects of morphine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

The effect of rifampin administration on the disposition of fexofenadine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Effects of rifampin on the pharmacokinetics and pharmacodynamics of glyburide and glipizide

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Pharmacogenetics of warfarin elimination and its clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Expression and induction of CYP1A1/1A2, CYP2A6 and CYP3A4 in primary cultures of human hepatocytes: a 10-year follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

A potentially hazardous interaction between erythromycin and midazolam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Dose of midazolam should be reduced during diltiazem and verapamil treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Effect of route of administration of fluconazole on the interaction between fluconazole and midazolam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Grapefruit juice has minimal effects on plasma concentrations of lovastatin-derived 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Interaction between grapefruit juice and midazolam in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

A pharmacokinetic interaction between roxithromycin and midazolam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

I.v. fentanyl decreases the clearance of midazolam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Cimetidine and ranitidine increase midazolam bioavailability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Mechanism-based enzyme inactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Use of Fresh and Cryopreserved Human Liver Slices in Toxicology with Special Reference to In vitro Induction of Cytochrome P450

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Induction of cytochrome P450 isoenzymes in cultured precision-cut rat and human liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

3,3'-Diindolylmethane induces CYP1A2 in cultured precision-cut human liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Induction of CYP3A isoforms in cultured precision-cut human liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Relative bioavailability of Neoral versus Sandimmune in the presence of a P450IIIA and P-glycoprotein inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Intestinal transport of beta-lactam antibiotics: analysis of the affinity at the H+/peptide symporter (PEPT1), the uptake into Caco-2 cell monolayers and the transepithelial flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Influence of renal failure on cytochrome P 450 activity in hypertensive patients using a "cocktail" of antipyrine and nifedipine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Validation of the five-drug "Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

All-trans-retinoic acid modulation of drug-metabolizing enzyme activities: investigation with selective metabolic drug probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

In vivo modulation of CYP enzymes by quinidine and rifampin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

A comprehensive account on the role of efflux transporters in the gastrointestinal absorption of 13 commonly used substrate drugs in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Oral bioavailability of digoxin is enhanced by talinolol: evidence for involvement of intestinal P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Unexpected effect of verapamil on oral bioavailability of the beta-blocker talinolol in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

Expression and regulation of cytochrome P450 enzymes in primary cultures of human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003252519

21 January 2018

Identifiers

DOI

10.1177/0091270003252519

1 reference

6 August 2017

1 reference