(Q35131209)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

title

The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

5

Chaitan Khosla

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

author name string

Yinyan Tang

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Irimpan I Mathews

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

David E Cane

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

language of work or name

English

0 references

publication date

14 July 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

volume

103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

page(s)

11124-11129

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

issue

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase

27 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Structure and molecular organization of mammalian fatty acid synthase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Refinement of macromolecular structures by the maximum-likelihood method

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

An antibiotic factory caught in action

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Polyketide and nonribosomal peptide antibiotics: modularity and versatility

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

The structure of docking domains in modular polyketide synthases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA:ACP transacylase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Automated main-chain model building by template matching and iterative fragment extension

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Crystal structure of the priming beta-ketosynthase from the R1128 polyketide biosynthetic pathway

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Molecular architecture and mechanism of an icosahedral pyruvate dehydrogenase complex: a multifunctional catalytic machine

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Substructure solution with SHELXD

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Intermodular communication in polyketide synthases: comparing the role of protein-protein interactions to those in other multidomain proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Human fatty acid synthase: role of interdomain in the formation of catalytically active synthase dimer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Substrate specificity of the loading didomain of the erythromycin polyketide synthase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

The 1.8 A crystal structure and active-site architecture of beta-ketoacyl-acyl carrier protein synthase III (FabH) from escherichia coli

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

The X-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-A resolution. Crystal structure of a fatty acid synthase component

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Improved methods for building protein models in electron density maps and the location of errors in these models

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Modular organization of genes required for complex polyketide biosynthesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636687

Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analogues.

13 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601924103

Mechanistic analysis of acyl transferase domain exchange in polyketide synthase modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601924103

Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601924103

Intermodular communication in modular polyketide synthases: structural and mutational analysis of linker mediated protein-protein recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601924103

The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601924103

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601924103

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601924103

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601924103

Dissecting and exploiting intermodular communication in polyketide synthases

21 January 2018

1 reference

12 December 2020

Architecture of mammalian fatty acid synthase at 4.5 A resolution

1 reference

12 December 2020

Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases

1 reference

12 December 2020

Harnessing the biosynthetic code: combinations, permutations, and mutations

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0601924103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference