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Costimulation of T cells by OX40, 4-1BB, and CD27.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12787564
retrieved
6 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Costimulation of T cells by OX40, 4-1BB, and CD27.
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12787564
retrieved
6 August 2017
author name string
Michael Croft
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12787564
retrieved
6 August 2017
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
1 June 2003
1 reference
stated in
Europe PubMed Central
PubMed ID
12787564
retrieved
6 August 2017
published in
Cytokine and Growth Factor Reviews
1 reference
stated in
Europe PubMed Central
PubMed ID
12787564
retrieved
6 August 2017
volume
14
1 reference
stated in
Europe PubMed Central
PubMed ID
12787564
retrieved
6 August 2017
page(s)
265-273
1 reference
stated in
Europe PubMed Central
PubMed ID
12787564
retrieved
6 August 2017
issue
3-4
1 reference
stated in
Europe PubMed Central
PubMed ID
12787564
retrieved
6 August 2017
cites work
Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
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7 January 2021
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inferred from DOI database lookup
The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
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7 January 2021
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inferred from DOI database lookup
The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
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7 January 2021
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Expression of CD134 (0X-40) on T cells during the first 100 days following allogeneic bone marrow transplantation as a marker for lymphocyte activation and therapy-resistant graft-versus-host disease.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
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7 January 2021
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inferred from DOI database lookup
Presence of the T-cell activation marker OX-40 on tumor infiltrating lymphocytes and draining lymph node cells from patients with melanoma and head and neck cancers
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
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7 January 2021
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CD134/OX40 expression by synovial fluid CD4+ T lymphocytes in chronic synovitis.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
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7 January 2021
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inferred from DOI database lookup
Contribution of OX40/OX40 ligand interaction to the pathogenesis of rheumatoid arthritis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
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7 January 2021
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The expression of OX40 in immunologically mediated diseases of the gastrointestinal tract (celiac disease, Crohn's disease, ulcerative colitis)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of allergic inflammation in a murine model of asthma is dependent on the costimulatory receptor OX40.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of gp34 (OX40 ligand) and OX40 on human T cell clones
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple levels of activation of murine CD8(+) intraepithelial lymphocytes defined by OX40 (CD134) expression: effects on cell-mediated cytotoxicity, IFN-gamma, and IL-10 regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human OX40/gp34 system directly mediates adhesion of activated T cells to vascular endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of lymphocyte-endothelial receptor-ligand pairs, alpha4beta7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
cDNA sequences of two inducible T-cell genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of 4-1BB expression by cell-cell interactions and the cytokines, interleukin-2 and interleukin-4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Co-stimulation of antigen-specific CD4 T cells by 4-1BB ligand
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional CD137 receptors are expressed by eosinophils from patients with IgE-mediated allergic responses but not by eosinophils from patients with non-IgE-mediated eosinophilic disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The potential roles of 4-1BB costimulation in HIV type 1 infection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
4-1BB T-cell antigen binds to mature B cells and macrophages, and costimulates anti-mu-primed splenic B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and expression of murine CD27: comparison with 4-1BB, another lymphocyte-specific member of the nerve growth factor receptor family.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD27/CD70 interaction directly drives B cell IgG and IgM synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of murine CD70 by molecular cloning and mAb.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL Responses after virus infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ox40-ligand has a critical costimulatory role in dendritic cell:T cell interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Danger and OX40 receptor signaling synergize to enhance memory T cell survival by inhibiting peripheral deletion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4 T cell traffic control: in vivo evidence that ligation of OX40 on CD4 T cells by OX40-ligand expressed on dendritic cells leads to the accumulation of CD4 T cells in B follicles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
4-1BB (CD137) controls the clonal expansion and survival of CD8 T cells in vivo but does not contribute to the development of cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In Vivo Triggering Through 4-1BB Enables Th-Independent Priming of CTL in the Presence of an Intact CD28 Costimulatory Pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD27 is required for generation and long-term maintenance of T cell immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNgamma-mediated B cell depletion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-tumor immunity elicited by a recombinant vaccinia virus expressing CD70 (CD27L).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of tumor-specific T cell memory by NK cell–mediated tumor rejection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of OX40 signal transduction pathways leads to tumor necrosis factor receptor-associated factor (TRAF) 2- and TRAF5-mediated NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
4-1BB co-stimulation enhances human CD8(+) T cell priming by augmenting the proliferation and survival of effector CD8(+) T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Engagement of the OX-40 receptor in vivo enhances antitumor immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective T cell priming associated with aging can be rescued by signaling through 4-1BB (CD137).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ox40 costimulation enhances the development of T cell responses induced by dendritic cells in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4 T cell cytokine differentiation: the B cell activation molecule, OX40 ligand, instructs CD4 T cells to express interleukin 4 and upregulates expression of the chemokine receptor, Blr-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Critical involvement of OX40 ligand signals in the T cell priming events during experimental autoimmune encephalomyelitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD134L expression on dendritic cells in the mesenteric lymph nodes drives colitis in T cell-restored SCID mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human 4-1BB regulates CD28 co-stimulation to promote Th1 cell responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antigen-presenting cell-derived signals determine expression levels of CD70 on primed T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phenotype and function of human B cells expressing CD70 (CD27 ligand)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900025-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1359-6101(03)00025-X
1 reference
stated in
Europe PubMed Central
PubMed ID
12787564
retrieved
6 August 2017
PubMed ID
12787564
1 reference
stated in
Europe PubMed Central
PubMed ID
12787564
retrieved
6 August 2017
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