(Q35163621)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Metalloprotease NleC suppresses host NF-κB/inflammatory responses by cleaving p65 and interfering with the p65/RPS3 interaction (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Andrea Hodgson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Eric M Wier

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Kai Fu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Hongbing Yu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Wenxin Zheng

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Ho Pan Sham

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Kaitlin Johnson

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Scott Bailey

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Bruce A Vallance

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Fengyi Wan

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

publication date

10 March 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

e1004705

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

2 March 2020

copyright license

start time

10 March 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4355070/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The Structure and Specificity of the Type III Secretion System Effector NleC Suggest a DNA Mimicry Mechanism of Substrate Recognition

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Structure and mechanism of a type III secretion protease, NleC

28 July 2018

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Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells.

28 July 2018

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The apoptogenic toxin AIP56 is a metalloprotease A-B toxin that cleaves NF-κb P65

28 July 2018

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Identification of an N-terminal truncation of the NF-κB p65 subunit that specifically modulates ribosomal protein S3-dependent NF-κB gene expression.

28 July 2018

1 reference

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Understanding the substrate specificity of conventional calpains.

28 July 2018

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Quantitative proteomic analysis of type III secretome of enteropathogenic Escherichia coli reveals an expanded effector repertoire for attaching/effacing bacterial pathogens

28 July 2018

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Functional differences and interactions between the Escherichia coli type III secretion system effectors NleH1 and NleH2.

28 July 2018

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Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions

28 July 2018

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Subversion of innate immune responses by bacterial hindrance of NF-κB pathway

28 July 2018

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The Trypanosoma cruzi protease cruzain mediates immune evasion

28 July 2018

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C/EBPα, C/EBPα oncoproteins, or C/EBPβ preferentially bind NF-κB p50 compared with p65, focusing therapeutic targeting on the C/EBP:p50 interaction

28 July 2018

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The pathogenic Escherichia coli type III secreted protease NleC degrades the host acetyltransferase p300.

28 July 2018

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Attaching and effacing bacterial effector NleC suppresses epithelial inflammatory responses by inhibiting NF-κB and p38 mitogen-activated protein kinase activation.

28 July 2018

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Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements

28 July 2018

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IKKβ phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7

28 July 2018

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Modulation of NF-κB signalling by microbial pathogens

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

NleC, a type III secretion protease, compromises NF-κB activation by targeting p65/RelA

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Proteasome-independent degradation of canonical NFkappaB complex components by the NleC protein of pathogenic Escherichia coli

28 July 2018

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Metalloprotease type III effectors that specifically cleave JNK and NF-κB

28 July 2018

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Enteropathogenic E. coli non-LEE encoded effectors NleH1 and NleH2 attenuate NF-κB activation.

28 July 2018

1 reference

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Cleavage of the NF-κB Family Protein p65/RelA by the Chlamydial Protease-like Activity Factor (CPAF) Impairs Proinflammatory Signaling in Cells Infected with Chlamydiae

28 July 2018

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Inhibition of NF-κB Signaling in Human Dendritic Cells by the Enteropathogenic Escherichia coli Effector Protein NleE

28 July 2018

1 reference

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The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

The type III secretion effector NleE inhibits NF-kappaB activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Specification of DNA binding activity of NF-kappaB proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Modulation of innate immune signalling pathways by viral proteins

28 July 2018

1 reference

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Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

A comprehensive proteomic analysis of the type III secretome of Citrobacter rodentium

28 July 2018

1 reference

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The nuclear signaling of NF-kappaB: current knowledge, new insights, and future perspectives

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Regulation and function of NF-kappaB transcription factors in the immune system

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Caspase-3-mediated cleavage of p65/RelA results in a carboxy-terminal fragment that inhibits IkappaBalpha and enhances HIV-1 replication in human T lymphocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Regulation of expression and secretion of NleH, a new non-locus of enterocyte effacement-encoded effector in Citrobacter rodentium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Type III secretion systems and disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Chlamydial CT441 is a PDZ domain-containing tail-specific protease that interferes with the NF-kappaB pathway of immune response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Enteropathogenic Escherichia coli (EPEC) inactivate innate immune responses prior to compromising epithelial barrier function.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Cleavage of p65/RelA of the NF-kappaB pathway by Chlamydia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

An extensive repertoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their dissemination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Modulation of tumor necrosis factor by microbial pathogens

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Citrobacter rodentium of mice and man.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

28 July 2018

Signaling to NF-kappaB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Dissecting virulence: systematic and functional analyses of a pathogenicity island

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Salmonella SipA polymerizes actin by stapling filaments with nonglobular protein arms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Diarrhoeagenic Escherichia coli--an emerging problem?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Type III protein secretion systems in bacterial pathogens of animals and plants

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Adherence of Shigella flexneri to guinea pig intestinal cells is mediated by a mucosal adhesion.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

A low-temperature method for the isolation of small-intestinal epithelium along the crypt-villus axis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Overexpression of the nuclear factor-κB subunit c-Rel protects against human islet cell death in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

NF-kappaB activity marks cells engaged in receptor editing

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Suppression of experimental colitis by intestinal mononuclear phagocytes.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Inhibition of lipopolysaccharide-induced macrophage IL-12 production by Leishmania mexicana amastigotes: the role of cysteine peptidases and the NF-kappaB signaling pathway

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Pathogenic Escherichia coli

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

NF-kappaB and virus infection: who controls whom

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Interactions between enteropathogenic Escherichia coli and host epithelial cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355070

Infection strategies of enteric pathogenic Escherichia coli

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004705

Proteolytic Cleavage of the p65-RelA Subunit of NF-κB during Poliovirus Infection

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004705

Bacterial effector interplay: a new way to view effector function.

21 January 2018

1 reference

12 December 2020

Use of Percoll density gradients for studying the attachment of bacteria to oral epithelial cells

1 reference

12 December 2020

Identification of oral bacteria associated with crevicular epithelial cells from chronic periodontitis lesions

1 reference

12 December 2020

Host-microbe interactions: bacteria

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1004705

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

25756944

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25756944%20AND%20SRC:MED&resulttype=core&format=json