(Q35165706)

6 August 2017

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title

The yin and yang of E2F-1: balancing life and death (English)

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6 August 2017

Nicholas B La Thangue

series ordinal

1

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6 August 2017

1 July 2003

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6 August 2017

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6 August 2017

5

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6 August 2017

587-589

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6 August 2017

7

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https://scigraph.springernature.com/pub.10.1038/ncb0703-587

6 August 2017

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cites work

E2F and cell cycle control: a double-edged sword

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

The E2F1-3 transcription factors are essential for cellular proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

ARF differentially modulates apoptosis induced by E2F1 and Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

Chk2 activates E2F-1 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

7 January 2021

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

7 January 2021

Chk1 and Chk2 kinases in checkpoint control and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCB0703-587

7 January 2021

Identifiers

DOI

10.1038/NCB0703-587

1 reference

6 August 2017

1 reference

PubMed ID

12833056