(Q35167516)

6 August 2017

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title

Functional genomics and proteomics: charting a multidimensional map of the yeast cell (English)

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6 August 2017

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Gary D Bader

1

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author name string

Adrian Heilbut

2

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6 August 2017

Brenda Andrews

3

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6 August 2017

Mike Tyers

4

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6 August 2017

Timothy Hughes

5

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6 August 2017

Charles Boone

6

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6 August 2017

language of work or name

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1 July 2003

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6 August 2017

Trends in Cell Biology

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6 August 2017

13

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6 August 2017

344-356

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6 August 2017

7

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Proteomics. Proteomics in genomeland

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Genomics. A crisis in postgenomic nomenclature.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Computational modeling of the EGF-receptor system: a paradigm for systems biology

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Metabolic modeling of microbial strains in silico.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Testing a mathematical model of the yeast cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

From molecular to modular cell biology

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

A new approach to decoding life: systems biology

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Gene expression and the myth of the average cell

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Treasures and traps in genome-wide data sets: case examples from yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

The complete DNA sequence of yeast chromosome III

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

BIND--The Biomolecular Interaction Network Database

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

DIP, the Database of Interacting Proteins: a research tool for studying cellular networks of protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

MINT: a Molecular INTeraction database

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

MIPS: a database for genomes and protein sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Saccharomyces Genome Database (SGD) provides secondary gene annotation using the Gene Ontology (GO)

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Comparative assessment of large-scale data sets of protein-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Analyzing yeast protein-protein interaction data obtained from different sources

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Transcriptional regulatory networks in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Systematic genetic analysis with ordered arrays of yeast deletion mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Modelling cellular behaviour

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Metabolic flux balance analysis and the in silico analysis of Escherichia coli K-12 gene deletions

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Initial sequencing and analysis of the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

The Sequence of the Human Genome

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

1 reference

7 January 2021

WIT: integrated system for high-throughput genome sequence analysis and metabolic reconstruction

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Evaluation of computational metabolic-pathway predictions for Helicobacter pylori.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Current methods of gene prediction, their strengths and weaknesses

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Surveying Saccharomyces genomes to identify functional elements by comparative DNA sequence analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

An integrated approach for finding overlooked genes in yeast.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Experimental annotation of the human genome using microarray technology

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

WorfDB: the Caenorhabditis elegans ORFeome Database

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

A mouse phenome project

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Systematic identification of pathways that couple cell growth and division in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Functional profiling of the Saccharomyces cerevisiae genome

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Novel strategies in antifungal lead discovery

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Systematic screen for human disease genes in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

RNAi analysis of genes expressed in the ovary of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Reverse genetics of essential genes in tissue-culture cells: 'dead cells talking'.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Cell-biological applications of transfected-cell microarrays

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Tissue microarrays for high-throughput molecular profiling of tumor specimens

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Quantitative monitoring of gene expression patterns with a complementary DNA microarray

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Gene expression analysis using oligonucleotide arrays produced by maskless photolithography

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Integrated genomic and proteomic analyses of a systematically perturbed metabolic network

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

A relationship between gene expression and protein interactions on the proteome scale: analysis of the bacteriophage T7 and the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Relating whole-genome expression data with protein-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Cluster analysis and display of genome-wide expression patterns

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Large-scale prediction of Saccharomyces cerevisiae gene function using overlapping transcriptional clusters

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Functional discovery via a compendium of expression profiles

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Systematic determination of genetic network architecture

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

ChIP-chip: a genomic approach for identifying transcription factor binding sites

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Dot1p modulates silencing in yeast by methylation of the nucleosome core

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric region

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Inferring subnetworks from perturbed expression profiles.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Assigning numbers to the arrows: parameterizing a gene regulation network by using accurate expression kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Discovering regulatory and signalling circuits in molecular interaction networks

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

1 reference

7 January 2021

A comprehensive two-hybrid analysis to explore the yeast protein interactome

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Functional organization of the yeast proteome by systematic analysis of protein complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Bridging structural biology and genomics: assessing protein interaction data with known complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Protein interaction verification and functional annotation by integrated analysis of genome-scale data.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

A network of protein-protein interactions in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Error and attack tolerance of complex networks

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Proteomics. Integrating interactomes

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Protein interactions: two methods for assessment of the reliability of high throughput observations

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

An automated method for finding molecular complexes in large protein interaction networks

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Making the most of microarray data.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Predicting protein--protein interactions from primary structure

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Synthetic enhancement in gene interaction: a genetic tool come of age.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

The art and design of genetic screens: yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Principles for the buffering of genetic variation

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Subcellular localization of the yeast proteome

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Gene ontology: tool for the unification of biology

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Nuclear sequestration of the exchange factor Cdc24 by Far1 regulates cell polarity during yeast mating

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Macromolecular Architecture in Eukaryotic Cells Visualized by Cryoelectron Tomography

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Analysis of proteins and proteomes by mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Directed proteomic analysis of the human nucleolus

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Quantitative protein profiling using two-dimensional gel electrophoresis, isotope-coded affinity tag labeling, and mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Mapping sites of O-GlcNAc modification using affinity tags for serine and threonine post-translational modifications

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Genomic analysis of biochemical function.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Structural proteomics of an archaeon

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Global Efforts in Structural Genomics

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Structural genomics: an approach to the protein folding problem

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Coupling of folding and binding for unstructured proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

MODBASE, a database of annotated comparative protein structure models.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Completeness in structural genomics.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

A biochemical genomics approach for identifying genes by the activity of their products.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Analysis of yeast protein kinases using protein chips.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Computational cell biology: spatiotemporal simulation of cellular events

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Genomic expression programs in the response of yeast cells to environmental changes

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

1 reference

7 January 2021

Lethality and centrality in protein networks

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

The yeast protein interaction network evolves rapidly and contains few redundant duplicate genes

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Overview of the Alliance for Cellular Signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Integrating interactome, phenome, and transcriptome mapping data for the C. elegans germline

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

A biological atlas of functional maps

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

The Stanford Microarray Database: data access and quality assessment tools

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

TRANSFAC: transcriptional regulation, from patterns to profiles

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

1 reference

7 January 2021

From molecular activities and processes to biological function.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

GeneNet: a database on structure and functional organisation of gene networks

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

SeqHound: biological sequence and structure database as a platform for bioinformatics research

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Creating a bioinformatics nation

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Support vector machine classification and validation of cancer tissue samples using microarray expression data

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

A Bayesian system integrating expression data with sequence patterns for localizing proteins: comprehensive application to the yeast genome

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

SPINE: an integrated tracking database and data mining approach for identifying feasible targets in high-throughput structural proteomics

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

BioLayout--an automatic graph layout algorithm for similarity visualization.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

Interrelating different types of genomic data, from proteome to secretome: 'oming in on function

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900127-2

7 January 2021

10.1016/S0962-8924(03)00127-2

Identifiers

DOI

1 reference

6 August 2017

1 reference