(Q35173049)

6 August 2017

1 reference

title

Searching for the gatekeeper oncogene of prostate cancer (English)

1 reference

6 August 2017

1 reference

Edward P Gelmann

1

1 reference

6 August 2017

1 June 2003

1 reference

Critical Reviews in Oncology Hematology

6 August 2017

1 reference

6 August 2017

46 Suppl

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6 August 2017

S11-20

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Lessons from hereditary colorectal cancer

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

A genetic model for colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

beta-catenin signaling and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Localization of the gene for familial adenomatous polyposis on chromosome 5.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

APC mutations occur early during colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Mutations of the APC (adenomatous polyposis coli) gene in FAP (familial polyposis coli) patients and in sporadic colorectal tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Two androgen response regions cooperate in steroid hormone regulated activity of the prostate-specific antigen promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Multiple structural chromosome rearrangements, including del(7q) and del(10q), in an adenocarcinoma of the prostate

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Loss of heterozygosity of the retinoblastoma and adenomatous polyposis susceptibility gene loci and in chromosomes 10p, 10q and 16q in human prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Gain and loss of chromosomes 1, 7, 8, 10, 18, and Y in 46 prostate cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Allelic loss on chromosomes 8p, 22q and 18q (DCC) in human prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Allelic loss of chromosomes 16q and 10q in human prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Evaluation of linkage and association of HPC2/ELAC2 in patients with familial or sporadic prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Evidence for a prostate cancer susceptibility locus on the X chromosome.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

A candidate prostate cancer susceptibility gene at chromosome 17p

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Linkage of prostate cancer susceptibility loci to chromosome 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Prostate cancer susceptibility locus HPC1 in Utah high-risk pedigrees

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Low frequency of allelic imbalance at the prostate cancer susceptibility loci HPC1 and 1p36 in Swedish men with hereditary prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Linkage analyses at the chromosome 1 loci 1q24-25 (HPC1), 1q42.2-43 (PCAP), and 1p36 (CAPB) in families with hereditary prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Infrequent allelic imbalance at the major susceptibilityHPC1 locus in sporadic prostate tumours

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

In Swedish families with hereditary prostate cancer, linkage to the HPC1 locus on chromosome 1q24-25 is restricted to families with early-onset prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Analysis of HPC1, HPCX, and PCaP in Icelandic hereditary prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Germline mutations in the ribonuclease L gene in families showing linkage with HPC1

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Germline alterations of the RNASEL gene, a candidate HPC1 gene at 1q25, in patients and families with prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Predisposing gene for early-onset prostate cancer, localized on chromosome 1q42.2-43

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Analysis of chromosome 1q42.2-43 in 152 families with high risk of prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

A candidate gene approach within the susceptibility region PCaP on 1q42.2-43 excludes deleterious mutations of the PCTA-1 gene to be responsible for hereditary prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Physical and transcript map of the hereditary prostate cancer region at xq27.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Association of HPC2/ELAC2 genotypes and prostate cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Loss of chromosome arm 8p loci in prostate cancer: mapping by quantitative allelic imbalance

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Localization of a tumor suppressor gene associated with progression of human prostate cancer within a 1.2 Mb region of 8p22-p21.3.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Allelic loss of 8p sequences in prostatic intraepithelial neoplasia and carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Determination of a minimal deletion interval on chromosome band 8p21 in sporadic prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Roles for Nkx3.1 in prostate development and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

A novel human prostate-specific, androgen-regulated homeobox gene (NKX3.1) that maps to 8p21, a region frequently deleted in prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Expression profile of an androgen regulated prostate specific homeobox gene NKX3.1 in primary prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Prostate-specific and androgen-dependent expression of a novel homeobox gene.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Mediolateral patterning of somites: multiple axial signals, including Sonic hedgehog, regulate Nkx-3.1 expression.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Targeted disruption of the Nkx3.1 gene in mice results in morphogenetic defects of minor salivary glands: parallels to glandular duct morphogenesis in prostate

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

DNA-binding sequence of the human prostate-specific homeodomain protein NKX3.1.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

The smooth muscle gamma-actin gene promoter is a molecular target for the mouse bagpipe homologue, mNkx3-1, and serum response factor

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

NK-2 homeobox genes and heart development

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Nuclear magnetic resonance solution structure of the fushi tarazu homeodomain from Drosophila and comparison with the Antennapedia homeodomain

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Analysis of PTEN and the 10q23 region in primary prostate carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

PTEN: a tumour suppressor that functions as a phospholipid phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Mutation and expression analysis of the putative prostate tumour-suppressor gene PTEN

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

PTEN/MMAC1/TEP1 involvement in primary prostate cancers.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

PTEN/MMAC1 is infrequently mutated in pT2 and pT3 carcinomas of the prostate.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Infrequent genetic alterations of the PTEN gene in Japanese patients with sporadic prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Pten is essential for embryonic development and tumour suppression

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Inactivation of the PTEN tumor suppressor gene is associated with increased angiogenesis in clinically localized prostate carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Molecular biology of the androgen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

No evidence of germline PTEN mutations in familial prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

E-cadherin is a WT1 target gene

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Comparison of the DNA binding characteristics of the related zinc finger proteins WT1 and EGR1

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Multiple intracellular pathways induce expression of a zinc-finger encoding gene (EGR1): relationship to activation of the Na/H exchanger

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

EGR1 target genes in prostate carcinoma cells identified by microarray analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Egr1 transcription factor: multiple roles in prostate tumor cell growth and survival

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Impaired prostate tumorigenesis in Egr1-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Frequent and early loss of the EGR1 corepressor NAB2 in human prostate carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

Frequent hypermethylation of the RASSF1A gene in prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2803%2900060-X

7 January 2021

10.1016/S1040-8428(03)00060-X

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12850523