(Q35174458)

6 August 2017

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title

The role of mitochondria in the life of the nematode, Caenorhabditis elegans (English)

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6 August 2017

Caenorhabditis elegans

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1 reference

William Y Tsang

1

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author name string

Bernard D Lemire

series ordinal

2

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PubMed ID

12853115

6 August 2017

language of work or name

English

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publication date

1 July 2003

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Biochimica et Biophysica Acta

6 August 2017

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6 August 2017

1638

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6 August 2017

91-105

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6 August 2017

2

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Mitochondria: a historical review

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

The origin and early evolution of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

INTRAMITOCHONDRIAL FIBERS WITH DNA CHARACTERISTICS. I. FIXATION AND ELECTRON STAINING REACTIONS

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Transcription and replication of animal mitochondrial DNAs.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondria: beyond oxidative phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial medicine

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial diseases in man and mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial DNA in aging and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

A mitochondrial DNA clone is associated with increased risk for Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Marked increase in mitochondrial DNA deletion levels in the cerebral cortex of Huntington's disease patients

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mutations in SDHC cause autosomal dominant paraganglioma, type 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

The central role of the mitochondrial megachannel in apoptosis: evidence obtained with intact cells, isolated mitochondria, and purified protein complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondria, oxygen free radicals, and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

The embryonic cell lineage of the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Medical significance of Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

A role for Caenorhabditis elegans in understanding the function and interactions of human disease genes

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Genome sequence of the nematode C. elegans: a platform for investigating biology

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

1 reference

7 January 2021

Developmental regulation of energy metabolism in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Association of mitochondria with microtubules in cultured cells

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

A gene required for nuclear and mitochondrial attachment in the nematode Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Role of ANC-1 in tethering nuclei to the actin cytoskeleton.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Functional diversity in the dynamin family

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial gene expression during bovine cardiac growth and development.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

What regulates mitochondrial DNA copy number in animal cells?

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial genome content is regulated during nematode development

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Intersex, a temperature-sensitive mutant of the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Release of replication termination controls mitochondrial DNA copy number after depletion with 2',3'-dideoxycytidine

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Regulation of the expression of mitochondrial proteins: relationship between mtDNA copy number and cytochrome-c oxidase activity in human cells and tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial genome expression in a mutant strain of D. subobscura, an animal model for large scale mtDNA deletion

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Coordinate induction of energy gene expression in tissues of mitochondrial disease patients

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Stimulation of mitochondrial gene expression and proliferation of mitochondria following impairment of cellular energy transfer by inhibition of the phosphocreatine circuit in rat hearts

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Development and fertility in Caenorhabditis elegans clk-1 mutants depend upon transport of dietary coenzyme Q8 to mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Maternal inheritance of mammalian mitochondrial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial genetics: a paradigm for aging and degenerative diseases?

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial genetics and human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Modulating heteroplasmy

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Detection of deletions in the mitochondrial genome of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Increased frequency of deletions in the mitochondrial genome with age of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

High direct estimate of the mutation rate in the mitochondrial genome of Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Stable heteroplasmy but differential inheritance of a large mitochondrial DNA deletion in nematodes.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Stable heteroplasmy for a large-scale deletion in the coding region of Drosophila subobscura mitochondrial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Complete replacement of mitochondrial DNA in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Developmental changes in heteroplasmy level and mitochondrial gene expression in a Drosophila subobscura mitochondrial deletion mutant.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Rearrangements of human mitochondrial DNA (mtDNA): new insights into the regulation of mtDNA copy number and gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

The nuclear genome is involved in heteroplasmy control in a mitochondrial mutant strain of Drosophila subobscura

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

The art and design of genetic screens: caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial respiratory chain diseases and mutations in nuclear DNA: a promising start?

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Reverse genetics by chemical mutagenesis in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial respiratory chain deficiency in Caenorhabditis elegans results in developmental arrest and increased life span

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mutant NDUFV1 subunit of mitochondrial complex I causes leukodystrophy and myoclonic epilepsy.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Large-scale deletion and point mutations of the nuclear NDUFV1 and NDUFS1 genes in mitochondrial complex I deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Ubiquinone is necessary for Caenorhabditis elegans development at mitochondrial and non-mitochondrial sites.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mammalian TOR: a homeostatic ATP sensor

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Quinones as the redox signal for the arc two-component system of bacteria

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Specific interference by ingested dsRNA

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

RNAi in C. elegans: soaking in the genome sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

1 reference

7 January 2021

RNA interference: genetic wand and genetic watchdog

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Functional genomic analysis of C. elegans chromosome I by systematic RNA interference

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Embryonic tissue differentiation in Caenorhabditis elegans requires dif-1, a gene homologous to mitochondrial solute carriers

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial medicine

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Increased mitochondrial mass in mitochondrial myopathy mice

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial ATP synthase controls larval development cell nonautonomously in Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

The chemistry of free radicals

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Reactive oxygen species, mitochondria, apoptosis and aging.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Aging: a theory based on free radical and radiation chemistry

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

A methyl viologen-sensitive mutant of the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Protein oxidation during aging of the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Rapid accumulation of fluorescent material with aging in an oxygen-sensitive mutant mev-1 of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial mutations differentially affect aging, mutability and anesthetic sensitivity in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Extension of Life-Span with Superoxide Dismutase/Catalase Mimetics

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

No increase in lifespan in Caenorhabditis elegans upon treatment with the superoxide dismutase mimetic EUK-8

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Prevalence of SDHB, SDHC, and SDHD germline mutations in clinic patients with head and neck paragangliomas

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

GAS-1: a mitochondrial protein controls sensitivity to volatile anesthetics in the nematode Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial expression and function of GAS-1 in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Rates of behavior and aging specified by mitochondrial function during development

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

The COQ7 gene encodes a protein in saccharomyces cerevisiae necessary for ubiquinone biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Role of complex II in anaerobic respiration of the parasite mitochondria from Ascaris suum and Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Rhodoquinone and complex II of the electron transport chain in anaerobically functioning eukaryotes

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Apparent uncoupling of energy production and consumption in long-lived Clk mutants of Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Metabolism and aging in the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

clk-1, mitochondria, and physiological rates

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Coenzyme Q is an obligatory cofactor for uncoupling protein function

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

The genetics of caloric restriction in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

Determination of life-span in Caenorhabditis elegans by four clock genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2803%2900079-6

7 January 2021

10.1016/S0925-4439(03)00079-6

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12853115