(Q35176342)

6 August 2017

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title

Ligand-dependent regulation of T cell development and activation (English)

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6 August 2017

1

Ronald N Germain

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6 August 2017

language of work or name

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1 January 2003

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6 August 2017

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6 August 2017

volume

27

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6 August 2017

issue

2-3

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6 August 2017

page(s)

277-286

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Signals through CD8 or CD4 can induce commitment to the CD4 lineage in the thymus.

6 August 2017

cites work

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12 December 2020

MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.

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12 December 2020

Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells

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12 December 2020

Cross-antagonism of a T cell clone expressing two distinct T cell receptors

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12 December 2020

Dynamic visualization of a joint-specific autoimmune response through positron emission tomography

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12 December 2020

The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation

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12 December 2020

CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling

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12 December 2020

T-cell development and the CD4-CD8 lineage decision

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12 December 2020

Two-photon imaging of lymphocyte motility and antigen response in intact lymph node

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12 December 2020

Dynamics of thymocyte-stromal cell interactions visualized by two-photon microscopy.

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12 December 2020

Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection.

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12 December 2020

Kinetic proofreading in T-cell receptor signal transduction

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12 December 2020

Molecular mechanisms for lineage commitment in T cell development

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12 December 2020

The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells

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12 December 2020

In vivo visualization of gene expression using magnetic resonance imaging

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12 December 2020

Cutting edge: antigen-independent CD8 T cell proliferation.

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12 December 2020

Selective events in T cell development

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12 December 2020

Erratum: Costimulation and endogenous MHC ligands contribute to T cell recognition

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12 December 2020

Class II essential for CD4 survival

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12 December 2020

T-cell antigen receptor genes and T-cell recognition

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12 December 2020

Opening a window on thymic positive selection: developmental changes in the influence of cosignaling by integrins and CD28 on selection events induced by TCR engagement

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12 December 2020

Differential requirements for survival and proliferation of CD8 naïve or memory T cells

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12 December 2020

Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin

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12 December 2020

Kinetic discrimination in T-cell activation

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12 December 2020

Ultrasensitivity in the mitogen-activated protein kinase cascade

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12 December 2020

The expression of CD4 and CD8 accessory molecules on mature T cells is not random but correlates with the specificity of the alpha beta receptor for antigen

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12 December 2020

TCR signaling for initiation and completion of thymocyte positive selection has distinct requirements for ligand quality and presenting cell type.

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12 December 2020

Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation.

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12 December 2020

MHC-dependent survival of naïve T cells? A complicated answer to a simple question

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12 December 2020

The art of the probable: system control in the adaptive immune system

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12 December 2020

Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire

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12 December 2020

Systems biology: a brief overview

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12 December 2020

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

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12 December 2020

How alpha beta T cells deal with induced TCR alpha ablation

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12 December 2020

Structural basis of T cell recognition

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12 December 2020

Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes

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12 December 2020

Control of homeostasis of CD8+ memory T cells by opposing cytokines.

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12 December 2020

Association of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transduction

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12 December 2020

Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory

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12 December 2020

Cutting edge: thymic selection and autoreactivity are regulated by multiple coreceptors involved in T cell activation

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12 December 2020

MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation

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12 December 2020

The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate.

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12 December 2020

Information transfer at the immunological synapse.

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12 December 2020

Response to 'Class II essential for CD4 survival'

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12 December 2020

Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage.

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12 December 2020

Dynamic imaging of T cell-dendritic cell interactions in lymph nodes

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12 December 2020

Development of the CD4 and CD8 lineage of T cells: instruction versus selection

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12 December 2020

Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes

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12 December 2020

Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells

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12 December 2020

Measurement of molecular interactions in living cells by fluorescence resonance energy transfer between variants of the green fluorescent protein

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12 December 2020

Constitutive Tyrosine Phosphorylation of the T-Cell Receptor (TCR) ζ Subunit: Regulation of TCR-Associated Protein Tyrosine Kinase Activity by TCR ζ

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12 December 2020

Bioluminescence imaging of lymphocyte trafficking in vivo.

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12 December 2020

Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes

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12 December 2020

Identifiers

DOI

10.1385/IR:27:2-3:277

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Dimensions Publication ID

6 August 2017

1022832343

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