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Determinants of specificity in TGF-beta signal transduction.
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Europe PubMed Central
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13 November 2019
title
Determinants of specificity in TGF-beta signal transduction
(English)
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13 November 2019
author
David Wotton
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4
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317013
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13 November 2019
Joan Massagué Solé
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7
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13 November 2019
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Y G Chen
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1
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13 November 2019
A Hata
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2
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13 November 2019
R S Lo
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3
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13 November 2019
Y Shi
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5
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13 November 2019
N Pavletich
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6
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13 November 2019
publication date
1 July 1998
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13 November 2019
published in
Genes & Development
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13 November 2019
volume
12
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13 November 2019
page(s)
2144-2152
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13 November 2019
issue
14
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13 November 2019
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Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads
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Signaling through scaffold, anchoring, and adaptor proteins
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Smad4 and FAST-1 in the assembly of activin-responsive factor
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13 July 2018
A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity
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Mechanism of TGFbeta receptor inhibition by FKBP12
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The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase
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Smad5 induces ventral fates in Xenopus embryo
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Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4
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MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling
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13 July 2018
Transcriptional regulation by transforming growth factor beta of the expression of retinoic acid and retinoid X receptor genes in osteoblastic cells is mediated through AP-1.
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13 July 2018
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13 July 2018
Identification of a potential regulator of early transcriptional responses to mesoderm inducers in the frog embryo.
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13 July 2018
Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth
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Receptor-associated Mad homologues synergize as effectors of the TGF-beta response
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A human Mad protein acting as a BMP-regulated transcriptional activator
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13 July 2018
Complementation between kinase-defective and activation-defective TGF-beta receptors reveals a novel form of receptor cooperativity essential for signaling.
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13 July 2018
Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components
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13 July 2018
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
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The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms
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13 July 2018
Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin
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13 July 2018
Characterization of type I receptors for transforming growth factor-beta and activin
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13 July 2018
Mechanism of activation of the TGF-beta receptor
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13 July 2018
Disruption of transforming growth factor beta signaling by a mutation that prevents transphosphorylation within the receptor complex.
1 reference
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13 July 2018
GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex
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13 July 2018
Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013
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13 July 2018
Activins and the receptor serine kinase superfamily
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13 July 2018
The transforming growth factor-beta family
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013
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13 July 2018
Distinct transforming growth factor-beta (TGF-beta) receptor subsets as determinants of cellular responsiveness to three TGF-beta isoforms.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013
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13 July 2018
Structural framework for the protein kinase family
1 reference
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PubMed Central
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13 July 2018
TGF beta signals through a heteromeric protein kinase receptor complex
1 reference
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13 July 2018
A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013
retrieved
26 September 2018
Xenopus mothers against decapentaplegic is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor.
1 reference
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013
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26 September 2018
Somatic in vivo alterations of the DPC4 gene at 18q21 in human lung cancers.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013
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26 September 2018
Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013
retrieved
26 September 2018
Identifiers
DOI
10.1101/GAD.12.14.2144
1 reference
stated in
Europe PubMed Central
PMCID
317013
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9679059%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
PMCID
317013
1 reference
stated in
Europe PubMed Central
PMCID
317013
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9679059%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
PubMed ID
9679059
1 reference
stated in
Europe PubMed Central
PMCID
317013
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9679059%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
ResearchGate publication ID
2423095
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